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Protein Overview: MAD2L1

General Information:
Name(s) found: MAD2L1 [HGNC (HUGO)]
Description(s) found:
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  • gi|950199|gb|AAC52060.1| mitotic feedback control protein Madp2 homolog [Homo sapiens] [NCBI NR]
  • pir||G01942 mitotic feedback control protein Madp2 homolog - human [NCBI NR]
  • gi|63991993|gb|AAY40945.1| unknown [Homo sapiens] [NCBI NR]
  • gi|4505067|ref|NP_002349.1| MAD2-like 1 [Homo sapiens] [NCBI NR]
  • gi|2463196|emb|CAA03943.1| MAD2 [Homo sapiens] [NCBI NR]
  • gi|189054055|dbj|BAG36562.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|1575534|gb|AAC50781.1| Mad2 [NCBI NR]
  • gi|15281316|dbj|BAB63410.1| MAD2 [Homo sapiens] [NCBI NR]
  • gi|13676561|gb|AAK38174.1| MAD2-like protein 1 [Homo sapiens] [NCBI NR]
  • gi|13543586|gb|AAH05945.1| MAD2 mitotic arrest deficient-like 1 (yeast) [Homo sapiens] [NCBI NR]
  • gi|12653177|gb|AAH00356.1| MAD2 mitotic arrest deficient-like 1 (yeast) [Homo sapiens] [NCBI NR]
  • gi|12230256|sp|Q13257.1|MD2L1_HUMAN RecName: Full=Mitotic spindle assembly checkpoint protein MAD2A; AltName: Full=MAD2-like 1; Short=HsMAD2 [NCBI NR]
  • gi|119625678|gb|EAX05273.1| MAD2 mitotic arrest deficient-like 1 (yeast), isoform CRA_d [Homo sapiens] [NCBI NR]
  • MAD2 mitotic arrest deficient-like 1 (yeast) [HGNC (HUGO)]
  • Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens GN=MAD2L1 PE=1 SV=1 [Swiss-Prot]
  • (Q13257) Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Swiss-Prot]
  • Mitotic spindle assembly checkpoint protein MAD2A [hmr_yeast5_DM3-1_pombe.fasta]
  • MAD2-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; mitotic arrest deficient, yeast, homolog-like 1 [HMR_022704.fasta]
  • MAD2-like 1; mitotic arrest deficient, yeast, homolog-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 [Human2242005.fasta]
  • MAD2-like 1 [Homo sapiens]gi|12653177|gb|AAH00356.1| MAD2-like 1 [Homo sapiens]gi|13543586|gb|AAH05945.1| MAD2-like 1 [Homo sapiens]gi|13676561|gb|AAK38174.1| MAD2-like protein 1 [Homo sapiens]gi|950199|gb|AAC52060.1| mitotic feedback control protein [nrdb_11152004_Chlamydomonas]
  • Mitotic spindle assembly checkpoint protein MAD2A (MAD2-like 1) (HsMAD2) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Mitotic spindle assembly checkpoint protein MAD2A [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_002358) MAD2-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; mitotic arrest deficient, yeast, homolog-like 1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • MAD2-like 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • MAD2-like 1; mitotic arrest deficient, yeast, homolog-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 [Homo sapiens] [HumanGallus06162005.fasta]
  • MAD2-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; mitotic arrest deficient, yeast, homolog-like 1 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • MAD2 mitotic arrest deficient-like 1 (yeast), isoform CRA_d [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • MAD2 mitotic arrest deficient-like 1 (yeast) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unknown [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • MAD2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • MAD2-like protein 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Mad2 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • mitotic feedback control protein Madp2 homolog [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=MAD2L1 Mitotic spindle assembly checkpoint protein MAD2A [human-ipi-250309-contam.fasta]
  • IPI:IPI00012369.1|SWISS-PROT:Q13257|ENSEMBL:ENSP00000296509|REFSEQ:NP_002349|H-INV:HIT000029548|VEGA:OTTHUMP00000163919 Tax_Id=9606 Gene_Symbol=MAD2L1 Mitotic spindle assembly checkpoint protein MAD2A [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=MAD2L1 Mitotic spindle assembly checkpoint protein MAD2A ENSG00000164109 IPI00012369 IPI00218096 [drosphohumanreversed.fasta]
  • mitotic spindle assembly checkpoint protein MAD2A [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q13257;Q53F56;Q548X9;Q6IRW7; RecName: Full=Mitotic spindle assembly checkpoint protein MAD2A; AltName: Full=Mitotic arrest deficient 2-like protein 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens GN=MAD2L1 [011711_HMR.fasta]
  • GeneSymbol=MAD2L1 Synonyms=HSMAD2|MAD2 mitotic spindle assembly checkpoint protein MAD2A [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Mitotic spindle assembly checkpoint protein MAD2A GN=MAD2L1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 205 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALQLSREQG ITLRGSAEIV AEFFSFGINS ILYQRGIYPS ETFTRVQKYG LTLLVTTDLE  60
   61 LIKYLNNVVE QLKDWLYKCS VQKLVVVISN IESGEVLERW QFDIECDKTA KDDSAPREKS 120
  121 QKAIQDEIRS VIRQITATVT FLPLLEVSCS FDLLIYTDKD LVVPEKWEES GPQFITNSEE 180
  181 VRLRSFTTTI HKVNSMVAYK IPVND

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 78.522879 The Mad2 spindle checkpoint protein possesses two distinct natively folded states

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.14424444268625 bayes_pls_golite062009
  • protein binding
    		•  0.856075580719879 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle