Protein Overview: MYH2

General Information:
Name(s) found:	MYH2 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|4808813\|gb\|AAD29950.1\| myosin heavy chain IIa [Homo sapiens] [NCBI NR] gi\|153792663\|ref\|NP_060004.3\| myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] [NCBI NR] gi\|153791586\|ref\|NP_001093582.1\| myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] [NCBI NR] gi\|13431716\|sp\|Q9UKX2.1\|MYH2_HUMAN RecName: Full=Myosin-2; AltName: Full=Myosin heavy chain 2; AltName: Full=Myosin heavy chain 2a; Short=MyHC-2a; AltName: Full=Myosin heavy chain IIa; Short=MyHC-IIa; AltName: Full=Myosin heavy chain, skeletal muscle, adu [NCBI NR] gi\|119610409\|gb\|EAW90003.1\| myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens] [NCBI NR] gi\|116497217\|gb\|AAI26410.1\| Myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] [NCBI NR] myosin, heavy chain 2, skeletal muscle, adult [HGNC (HUGO)] Myosin-2 OS=Homo sapiens GN=MYH2 PE=1 SV=1 [Swiss-Prot] Myosin heavy chain, skeletal muscle, adult 2 [hmr_yeast5_DM3-1_pombe.fasta] Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa)gi\|4808813\|gb\|AAD29950.1\| myosin heavy chain IIa [Homo sapiens] [nrdb_11152004_Chlamydomonas] Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Myosin heavy chain, skeletal muscle, adult 2 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_017534) myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] myosin heavy chain IIa [Homo sapiens] [NCBI-RefSeq_human_na_05-03-2007_con_reversed.fasta] Myosin-2 (Myosin heavy chain 2) (Myosin heavy chain 2a) (MyHC-2a) (Myosin heavy chain IIa) (MyHC-IIa) (Myosin heavy chain, skeletal muscle, adult 2) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] myosin, heavy polypeptide 2, skeletal muscle, adult [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] RecName: Full=Myosin-2; AltName: Full=Myosin heavy chain 2; AltName: Full=Myosin heavy chain 2a; Short=MyHC-2a; AltName: Full=Myosin heavy chain IIa; Short=MyHC-IIa; AltName: Full=Myosin heavy chain, skeletal muscle, adult 2 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=MYH2 Myosin-2 [human-ipi-250309-contam.fasta] IPI:IPI00007856.1\|SWISS-PROT:Q9UKX2\|TREMBL:B4DRV3\|ENSEMBL:ENSP00000245503;ENSP00000380367\|REFSEQ:NP_001093582;NP_060004\|H-INV:HIT000389001\|VEGA:OTTHUMP00000160894;OTTHUMP00000183201 Tax_Id=9606 Gene_Symbol=MYH2 Myosin-2 [ipi.HUMAN.fasta.20090807] Tax_Id=9606 Myosin-2 [IPI_human_3.26.fasta] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=MYH2 Myosin-2 ENSG00000125414 IPI00007856 IPI00555997 IPI00791763 [drosphohumanreversed.fasta] myosin-2 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q9UKX2;A0AVL4;Q14322;Q16229;Q86T56; RecName: Full=Myosin-2; AltName: Full=Myosin heavy chain 2; AltName: Full=Myosin heavy chain 2a; AltName: Full=Myosin heavy chain IIa; AltName: Full=Myosin heavy chain, skeletal muscle, adult 2; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Myosin-2 OS=Homo sapiens GN=MYH2 [011711_HMR.fasta] GeneSymbol=MYH2 Synonyms=MYH2A\|MYHSA2\|MYHas8\|MyHC-2A\|MyHC-IIa myosin-2 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00007856.1\|SWISS-PROT:Q9UKX2\|TREMBL:B4DRV3\|ENSEMBL:ENSP00000245503;ENSP00000380367\|REFSEQ:NP_001093582;NP_060004\|H-INV:HIT000389001\|VEGA:OTTHUMP00000160894 Tax_Id=9606 Gene_Symbol=MYH2 Myosin-2 [ipi.HUMAN.20110912.fasta] Myosin-2 GN=MYH2 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	1941 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDSELAVF GEAAPFLRKS ERERIEAQNR PFDAKTSVFV AEPKESFVKG TIQSREGGKV  60
   61 TVKTEGGATL TVKDDQVFPM NPPKYDKIED MAMMTHLHEP AVLYNLKERY AAWMIYTYSG 120
  121 LFCVTVNPYK WLPVYKPEVV TAYRGKKRQE APPHIFSISD NAYQFMLTDR ENQSILITGE 180
  181 SGAGKTVNTK RVIQYFATIA VTGEKKKEEI TSGKIQGTLE DQIISANPLL EAFGNAKTVR 240
  241 NDNSSRFGKF IRIHFGTTGK LASADIETYL LEKSRVVFQL KAERSYHIFY QITSNKKPEL 300
  301 IEMLLITTNP YDYPFVSQGE ISVASIDDQE ELMATDSAID ILGFTNEEKV SIYKLTGAVM 360
  361 HYGNLKFKQK QREEQAEPDG TEVADKAAYL QSLNSADLLK ALCYPRVKVG NEYVTKGQTV 420
  421 EQVSNAVGAL AKAVYEKMFL WMVARINQQL DTKQPRQYFI GVLDIAGFEI FDFNSLEQLC 480
  481 INFTNEKLQQ FFNHHMFVLE QEEYKKEGIE WTFIDFGMDL AACIELIEKP MGIFSILEEE 540
  541 CMFPKATDTS FKNKLYDQHL GKSANFQKPK VVKGKAEAHF ALIHYAGVVD YNITGWLEKN 600
  601 KDPLNETVVG LYQKSAMKTL AQLFSGAQTA EGEGAGGGAK KGGKKKGSSF QTVSALFREN 660
  661 LNKLMTNLRS THPHFVRCII PNETKTPGAM EHELVLHQLR CNGVLEGIRI CRKGFPSRIL 720
  721 YADFKQRYKV LNASAIPEGQ FIDSKKASEK LLASIDIDHT QYKFGHTKVF FKAGLLGLLE 780
  781 EMRDDKLAQL ITRTQARCRG FLARVEYQRM VERREAIFCI QYNIRSFMNV KHWPWMKLFF 840
  841 KIKPLLKSAE TEKEMATMKE EFQKIKDELA KSEAKRKELE EKMVTLLKEK NDLQLQVQAE 900
  901 AEGLADAEER CDQLIKTKIQ LEAKIKEVTE RAEDEEEINA ELTAKKRKLE DECSELKKDI 960
  961 DDLELTLAKV EKEKHATENK VKNLTEEMAG LDETIAKLTK EKKALQEAHQ QTLDDLQAEE1020
 1021 DKVNTLTKAK IKLEQQVDDL EGSLEQEKKL RMDLERAKRK LEGDLKLAQE SIMDIENEKQ1080
 1081 QLDEKLKKKE FEISNLQSKI EDEQALGIQL QKKIKELQAR IEELEEEIEA ERASRAKAEK1140
 1141 QRSDLSRELE EISERLEEAG GATSAQIEMN KKREAEFQKM RRDLEEATLQ HEATAATLRK1200
 1201 KHADSVAELG EQIDNLQRVK QKLEKEKSEM KMEIDDLASN VETVSKAKGN LEKMCRTLED1260
 1261 QLSELKSKEE EQQRLINDLT AQRGRLQTES GEFSRQLDEK EALVSQLSRG KQAFTQQIEE1320
 1321 LKRQLEEEIK AKNALAHALQ SSRHDCDLLR EQYEEEQESK AELQRALSKA NTEVAQWRTK1380
 1381 YETDAIQRTE ELEEAKKKLA QRLQAAEEHV EAVNAKCASL EKTKQRLQNE VEDLMLDVER1440
 1441 TNAACAALDK KQRNFDKILA EWKQKCEETH AELEASQKEA RSLGTELFKI KNAYEESLDQ1500
 1501 LETLKRENKN LQQEISDLTE QIAEGGKRIH ELEKIKKQVE QEKCELQAAL EEAEASLEHE1560
 1561 EGKILRIQLE LNQVKSEVDR KIAEKDEEID QLKRNHIRIV ESMQSTLDAE IRSRNDAIRL1620
 1621 KKKMEGDLNE MEIQLNHANR MAAEALRNYR NTQGILKDTQ IHLDDALRSQ EDLKEQLAMV1680
 1681 ERRANLLQAE IEELRATLEQ TERSRKIAEQ ELLDASERVQ LLHTQNTSLI NTKKKLETDI1740
 1741 SQMQGEMEDI LQEARNAEEK AKKAITDAAM MAEELKKEQD TSAHLERMKK NMEQTVKDLQ1800
 1801 LRLDEAEQLA LKGGKKQIQK LEARVRELEG EVESEQKRNA EAVKGLRKHE RRVKELTYQT1860
 1861 EEDRKNILRL QDLVDKLQAK VKSYKRQAEE AEEQSNTNLA KFRKLQHELE EAEERADIAE1920
 1921 SQVNKLRVKS REVHTKVISE E

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: MYH2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: