Protein Overview: SLC24A2

General Information:
Name(s) found:	SLC24A2 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|9966787\|ref\|NP_065077.1\| solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI NR] gi\|6650379\|gb\|AAF21810.1\|AF097366_1 cone sodium-calcium potassium exchanger [Homo sapiens] [NCBI NR] gi\|55661979\|emb\|CAH74108.1\| solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI NR] gi\|55661436\|emb\|CAH73020.1\| solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI NR] gi\|55660859\|emb\|CAH71736.1\| solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI NR] gi\|46854416\|gb\|AAH69622.1\| Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI NR] gi\|17865516\|sp\|Q9UI40.1\|NCKX2_HUMAN RecName: Full=Sodium/potassium/calcium exchanger 2; AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 2; AltName: Full=Retinal cone Na-Ca+K exchanger; AltName: Full=Solute carrier family 24 member 2; Flags: Precursor [NCBI NR] gi\|119579037\|gb\|EAW58633.1\| solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI NR] solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [HGNC (HUGO)] (Q9UI40) Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) [Swiss-Prot] Sodium/potassium/calcium exchanger 2 OS=Homo sapiens GN=SLC24A2 PE=1 SV=1 [Swiss-Prot] Splice isoform 1 of Q9UI40 [hmr_yeast5_DM3-1_pombe.fasta] solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens]gi\|46854416\|gb\|AAH69622.1\| Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens]gi\|55661979\|emb\|CAH74108.1\| OTTHUMP00000045115 [Homo s [nrdb_11152004_Chlamydomonas] Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splice Isoform 1 of Sodium/potassium/calcium exchanger 2 precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_020344) solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Sodium/potassium/calcium exchanger 2 precursor (Na(+)/K(+)/Ca(2+)-exchange protein 2) (Retinal cone Na-Ca+K exchanger) (Solute carrier family 24 member 2) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] cone sodium-calcium potassium exchanger [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform 1 of Sodium/potassium/calcium exchanger 2 precursor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 SPLICE ISOFORM 1 OF SODIUM/POTASSIUM/CALCIUM EXCHANGER 2 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=SLC24A2 Isoform 1 of Sodium/potassium/calcium exchanger 2 [human-ipi-250309-contam.fasta] solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 precursor [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta] solute carrier family 24 (sodium\/potassium\/calcium exchanger), member 2 [Homo sapiens] [nr-271106-contam.fasta] IPI:IPI00006444.1\|SWISS-PROT:Q9UI40-1\|ENSEMBL:ENSP00000344801\|REFSEQ:NP_065077\|H-INV:HIT000068478\|VEGA:OTTHUMP00000021125 Tax_Id=9606 Gene_Symbol=SLC24A2 Isoform 1 of Sodium/potassium/calcium exchanger 2 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=SLC24A2 Isoform 1 of Sodium/potassium/calcium exchanger 2 precursor ENSG00000155886 IPI00218809 IPI00006444 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=SLC24A2 Isoform 1 of Sodium/potassium/calcium exchanger 2 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] sodium/potassium/calcium exchanger 2 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Sodium/potassium/calcium exchanger 2 OS=Homo sapiens GN=SLC24A2 PE=2 SV=1 [UniProtHuman070710.fasta] Q9UI40;B7ZLL8;Q9NTN5;Q9NZQ4; RecName: Full=Sodium/potassium/calcium exchanger 2; AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 2; AltName: Full=Retinal cone Na-Ca+K exchanger; AltName: Full=Solute carrier family 24 member 2; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform 1 of Sodium/potassium/calcium exchanger 2 OS=Homo sapiens GN=SLC24A2 [011711_HMR.fasta] GeneSymbol=SLC24A2 Synonyms=FLJ45149\|NCKX2 sodium/potassium/calcium exchanger 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Sodium/potassium/calcium exchanger 2 GN=SLC24A2 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	661 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLQQSTTIT SLEKWCLDES LSGCRRHYSV KKKLKLIRVL GLFMGLVAIS TVSFSISAFS  60
   61 ETDTQSTGEA SVVSGPRVAQ GYHQRTLLDL NDKILDYTPQ PPLSKEGESE NSTDHAQGDY 120
  121 PKDIFSLEER RKGAIILHVI GMIYMFIALA IVCDEFFVPS LTVITEKLGI SDDVAGATFM 180
  181 AAGGSAPELF TSLIGVFIAH SNVGIGTIVG SAVFNILFVI GMCALFSREI LNLTWWPLFR 240
  241 DVSFYIVDLI MLIIFFLDNV IMWWESLLLL TAYFCYVVFM KFNVQVEKWV KQMINRNKVV 300
  301 KVTAPEAQAK PSAARDKDEP TLPAKPRLQR GGSSASLHNS LMRNSIFQLM IHTLDPLAEE 360
  361 LGSYGKLKYY DTMTEEGRFR EKASILHKIA KKKCHVDENE RQNGAANHVE KIELPNSTST 420
  421 DVEMTPSSDA SEPVQNGNLS HNIEGAEAQT ADEEEDQPLS LAWPSETRKQ VTFLIVFPIV 480
  481 FPLWITLPDV RKPSSRKFFP ITFFGSITWI AVFSYLMVWW AHQVGETIGI SEEIMGLTIL 540
  541 AAGTSIPDLI TSVIVARKGL GDMAVSSSVG SNIFDITVGL PLPWLLYTVI HRFQPVAVSS 600
  601 NGLFCAIVLL FIMLLFVILS IALCKWRMNK ILGFIMFGLY FVFLVVSVLL EDRILTCPVS 660
  661 I

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..119]	deduced	N/A	No confident structure predictions are available.
2	View Details	[120..296]	Pfam	41.79588	No description for PF01699.15 was found. No confident structure predictions are available.
3	View Details	[297..460]	deduced	N/A	No confident structure predictions are available.
4	View Details	[461..661]	Pfam	40.148742	No description for PF01699.15 was found. No confident structure predictions are available.

Protein Overview: SLC24A2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: