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Protein Overview: gi|6013006, gi|3...

General Information:
Name(s) found: gi|77176717 [NCBI NR]
gi|7657496 [NCBI NR]
gi|6013006 [NCBI NR]
gi|37574282 [NCBI NR]
gi|30583053 [NCBI NR]
gi|15929821 [NCBI NR]
gi|119628321 [NCBI NR]
gi|119628319 [NCBI NR]
Description(s) found:
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  • gi|77176717|gb|ABA64473.1| RAP1 [Homo sapiens] [NCBI NR]
  • gi|7657496|ref|NP_055319.1| RAB guanine nucleotide exchange factor (GEF) 1 [Homo sapiens] [NCBI NR]
  • gi|6013006|emb|CAB57359.1| Rab5 GDP/GTP exchange factor homologue [Homo sapiens] [NCBI NR]
  • gi|37574282|gb|AAQ93362.1| unknown [Homo sapiens] [NCBI NR]
  • gi|30583053|gb|AAP35771.1| putative Rab5 GDP/GTP exchange factor homologue [Homo sapiens] [NCBI NR]
  • gi|15929821|gb|AAH15330.1| RAB guanine nucleotide exchange factor (GEF) 1 [Homo sapiens] [NCBI NR]
  • gi|119628321|gb|EAX07916.1| RAB guanine nucleotide exchange factor (GEF) 1, isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119628319|gb|EAX07914.1| RAB guanine nucleotide exchange factor (GEF) 1, isoform CRA_b [Homo sapiens] [NCBI NR]
  • Rab5 GDP/GTP exchange factor homologue [hmr_yeast5_DM3-1_pombe.fasta]
  • RAB guanine nucleotide exchange factor (GEF) 1 [HMR_022704.fasta]
  • unknown [Homo sapiens]gi|30583053|gb|AAP35771.1| putative Rab5 GDP/GTP exchange factor homologue [Homo sapiens]gi|7657496|ref|NP_055319.1| RAB guanine nucleotide exchange factor (GEF) 1 [Homo sapiens]gi|15929821|gb|AAH15330.1| RAB guanine nucleotide ex [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Splice Isoform 2 of Rab5 GDP/GTP exchange factor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_014504) putative Rab5 GDP/GTP exchange factor homologue [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • RAB guanine nucleotide exchange factor (GEF) 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • RAB guanine nucleotide exchange factor (GEF) 1, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • RAP1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unknown [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • putative Rab5 GDP/GTP exchange factor homologue [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Rab5 GDP/GTP exchange factor homologue [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 2 of Rab5 GDP/GTP exchange factor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 2 OF RAB5 GDP/GTP EXCHANGE FACTOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • IPI:IPI00924641.1|SWISS-PROT:Q9UJ41-2|TREMBL:B3KMF1|ENSEMBL:ENSP00000284957;ENSP00000415815|REFSEQ:NP_055319|H-INV:HIT000245962|VEGA:OTTHUMP00000024929;OTTHUMP00000159944;OTTHUMP00000210543 Tax_Id=9606 Gene_Symbol=RABGEF1;KCTD7 Isoform 2 of Rab5 GDP/GTP e [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=RABGEF1;KCTD7 Isoform 2 of Rab5 GDP/GTP exchange factor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=RABGEF1 Isoform 2 of Rab5 GDP/GTP exchange factor [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta]
  • Isoform 2 of Rab5 GDP/GTP exchange factor OS=Homo sapiens GN=RABGEF1 [011711_HMR.fasta]
  • IPI:IPI00924641.1|SWISS-PROT:Q9UJ41-2|TREMBL:B3KMF1|ENSEMBL:ENSP00000284957;ENSP00000415815|REFSEQ:NP_055319|H-INV:HIT000245962|VEGA:OTTHUMP00000024929;OTTHUMP00000159944;OTTHUMP00000210543 Tax_Id=9606 Gene_Symbol=RABGEF1 Isoform 2 of Rab5 GDP/GTP exchange factor [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=RABGEF1 Synonyms=FLJ32302|RABEX5|rabex-5 rab5 GDP/GTP exchange factor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00924641.1|SWISS-PROT:Q9UJ41-2|TREMBL:A8K3R3;B3KMF1|ENSEMBL:ENSP00000284957;ENSP00000398177;ENSP00000415815;ENSP00000421124|REFSEQ:NP_055319|H-INV:HIT000245962|VEGA:OTTHUMP00000159944;OTTHUMP00000210543 Tax_Id=9606 Gene_Symbol=RABGEF1;KCTD7 Isoform 2 of Rab5 GDP/GTP exchange factor [ipi.HUMAN.20110912.fasta]
  • Isoform 2 of Rab5 GDP/GTP exchange factor GN=RABGEF1 [Doctor+uniprot-HUMAN-120911.fasta]
  • RAB guanine nucleotide exchange factor (GEF) 1, isoform CRA_b OS=Homo sapiens GN=RABGEF1 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
  • Isoform of Q9UJ41, Isoform 2 of Rab5 GDP/GTP exchange factor OS=Homo sapiens GN=RABGEF1 [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 491 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ IQEDWELAER  60
   61 LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR VGSKKEIQEA 120
  121 KAPSPSINRQ TSIETDRVSK EFIEFLKTFH KTGQEIYKQT KLFLEGMHYK RDLSIEEQSE 180
  181 CAQDFYHNVA ERMQTRGKVP PERVEKIMDQ IEKYIMTRLY KYVFCPETTD DEKKDLAIQK 240
  241 RIRALRWVTP QMLCVPVNED IPEVSDMVVK AITDIIEMDS KRVPRDKLAC ITKCSKHIFN 300
  301 AIKITKNEPA SADDFLPTLI YIVLKGNPPR LQSNIQYITR FCNPSRLMTG EDGYYFTNLC 360
  361 CAVAFIEKLD AQSLNLSQED FDRYMSGQTS PRKQEAESWS PDACLGVKQM YKNLDLLSQL 420
  421 NERQERIMNE AKKLEKDLID WTDGIAREVQ DIVEKYPLEI KPPNQPLAAI DSENVENDKL 480
  481 PPPLQPQVYA G

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..99] PSI-BLAST 18.30103 human Rabex-5 residues 1-74 in complex with Ubiquitin
    2 View Details [100..395] PSI-BLAST 89.221849 Crystal Structure of the Vps9 Domain of Rabex-5
    3 View Details [396..491] MSA 2.120992 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.248690472541603 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle