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Protein Overview: PAFAH1B1

General Information:
Name(s) found: PAFAH1B1 [HGNC (HUGO)]
Description(s) found:
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  • gi|4557741|ref|NP_000421.1| platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit [Homo sapiens] [NCBI NR]
  • gi|40352755|gb|AAH64638.1| Platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa [Homo sapiens] [NCBI NR]
  • gi|349826|gb|AAA02881.1| Miller-Dieker lissencephaly protein [NCBI NR]
  • gi|349824|gb|AAA02880.1| Miller-Dieker lissencephaly protein [NCBI NR]
  • gi|189053652|dbj|BAG35904.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|1850956|gb|AAC51111.1| platelet activating factor acetylhydrolase, brain isoform, 45 kDa subunit [Homo sapiens] [NCBI NR]
  • gi|15217063|gb|AAK92483.1|AF400434_1 platelet-activating factor acetyl hydrolase isoform Ib alpha subunit [Homo sapiens] [NCBI NR]
  • gi|119610942|gb|EAW90536.1| platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa [Homo sapiens] [NCBI NR]
  • gi|1170794|sp|P43034.2|LIS1_HUMAN RecName: Full=Platelet-activating factor acetylhydrolase IB subunit alpha; AltName: Full=PAF acetylhydrolase 45 kDa subunit; Short=PAF-AH 45 kDa subunit; AltName: Full=PAF-AH alpha; AltName: Full=PAFAH alpha; AltName: Ful [NCBI NR]
  • platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) [HGNC (HUGO)]
  • Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens GN=PAFAH1B1 PE=1 SV=2 [Swiss-Prot]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) [hmr_yeast5_DM3-1_pombe.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); lissencephaly 1 protein; Platelet-activating factor acetylhydrolase, isoform 1B, alpha subunit [HMR_022704.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); Platelet-activating factor acetylhydrolase, isoform 1B, alpha subunit; lissencephaly 1 protein [Human2242005.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) [Homo sapiens]gi|40352755|gb|AAH64638.1| Platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) [Homo sapiens]gi|15217063|gb|AAK92483.1| platelet-activati [nrdb_11152004_Chlamydomonas]
  • Platelet-activating factor acetylhydrolase IB alpha subunit (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • (NM_000430) platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); lissencephaly 1 protein; Platelet-activating factor acetylhydrolase, isoform 1B, alpha subunit [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Platelet-activating factor acetylhydrolase, isoform Ib, alPha subunit (45kD) [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); Platelet-activating factor acetylhydrolase, isoform 1B, alpha subunit; lissencephaly 1 protein [Homo sapiens] [HumanGallus06162005.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); lissencephaly 1 protein; Platelet-activating factor acetylhydrolase, isoform 1B, alpha subunit [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Platelet-activating factor acetylhydrolase IB subunit alpha (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) (Lissencephaly-1 protein) (LIS-1) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • platelet-activating factor acetyl hydrolase isoform Ib alpha subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • platelet activating factor acetylhydrolase, brain isoform, 45 kDa subunit [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Miller-Dieker lissencephaly protein [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE, ISOFORM IB, ALPHA SUBUNIT (45KD) [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Platelet-activating factor acetylhydrolase IB subunit alpha; AltName: Full=PAF acetylhydrolase 45 kDa subunit; Short=PAF-AH 45 kDa subunit; AltName: Full=PAF-AH alpha; AltName: Full=PAFAH alpha; AltName: Full=Lissencephaly-1 protein; Short=L [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PAFAH1B1 Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha [human-ipi-250309-contam.fasta]
  • platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta]
  • IPI:IPI00218728.4|SWISS-PROT:P43034-1|TREMBL:B2R7Q7;B4DZN3|ENSEMBL:ENSP00000380378|REFSEQ:NP_000421|H-INV:HIT000192196|VEGA:OTTHUMP00000182686 Tax_Id=9606 Gene_Symbol=PAFAH1B1 Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=PAFAH1B1 Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha ENSG00000007168 IPI00218728 IPI00760905 [drosphohumanreversed.fasta]
  • platelet-activating factor acetylhydrolase IB subunit alpha [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P43034;B2R7Q7;Q8WZ88;Q8WZ89; RecName: Full=Platelet-activating factor acetylhydrolase IB subunit alpha; AltName: Full=PAF acetylhydrolase 45 kDa subunit; AltName: Full=PAF-AH alpha; AltName: Full=Lissencephaly-1 protein; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens GN=PAFAH1B1 [011711_HMR.fasta]
  • IPI:IPI00218728.4|SWISS-PROT:P43034-1|TREMBL:B4DZN3|ENSEMBL:ENSP00000380378|REFSEQ:NP_000421|H-INV:HIT000192196|VEGA:OTTHUMP00000182686 Tax_Id=9606 Gene_Symbol=PAFAH1B1 Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha [ipi.HUMAN.fasta.20100406]
  • Platelet-activating factor acetylhydrolase IB subunit alpha n=35 Tax=Euteleostomi RepID=LIS1_HUMAN [UniProt_Xenopus_laevis_01-01-2011_reversed.fasta]
  • GeneSymbol=PAFAH1B1 Synonyms=LIS1|LIS2|MDCR|MDS|PAFAH platelet-activating factor acetylhydrolase IB subunit alpha [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00218728.4|SWISS-PROT:P43034-1|ENSEMBL:ENSP00000380378|REFSEQ:NP_000421|H-INV:HIT000192196 Tax_Id=9606 Gene_Symbol=PAFAH1B1 Isoform 1 of Platelet-activating factor acetylhydrolase IB subunit alpha [ipi.HUMAN.20110912.fasta]
  • Platelet-activating factor acetylhydrolase IB subunit alpha GN=PAFAH1B1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 410 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLSQRQRDE LNRAIADYLR SNGYEEAYSV FKKEAELDVN EELDKKYAGL LEKKWTSVIR  60
   61 LQKKVMELES KLNEAKEEFT SGGPLGQKRD PKEWIPRPPE KYALSGHRSP VTRVIFHPVF 120
  121 SVMVSASEDA TIKVWDYETG DFERTLKGHT DSVQDISFDH SGKLLASCSA DMTIKLWDFQ 180
  181 GFECIRTMHG HDHNVSSVAI MPNGDHIVSA SRDKTIKMWE VQTGYCVKTF TGHREWVRMV 240
  241 RPNQDGTLIA SCSNDQTVRV WVVATKECKA ELREHEHVVE CISWAPESSY SSISEATGSE 300
  301 TKKSGKPGPF LLSGSRDKTI KMWDVSTGMC LMTLVGHDNW VRGVLFHSGG KFILSCADDK 360
  361 TLRVWDYKNK RCMKTLNAHE HFVTSLDFHK TAPYVVTGSV DQTVKVWECR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle