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Protein Overview: CFB

General Information:
Name(s) found: CFB [HGNC (HUGO)]
Description(s) found:
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  • gi|67782358|ref|NP_001701.2| complement factor B preproprotein [Homo sapiens] [NCBI NR]
  • pir||BBHU complement factor B precursor [validated] - human [NCBI NR]
  • gi|584908|sp|P00751.2|CFAB_HUMAN RecName: Full=Complement factor B; AltName: Full=C3/C5 convertase; AltName: Full=Properdin factor B; AltName: Full=Glycine-rich beta glycoprotein; Short=GBG; AltName: Full=PBF2; Contains: RecName: Full=Complement factor B [NCBI NR]
  • gi|57209501|emb|CAI41726.1| B-factor, properdin [Homo sapiens] [NCBI NR]
  • gi|55961819|emb|CAI17456.1| complement factor B [Homo sapiens] [NCBI NR]
  • gi|4261689|gb|AAD13989.1|S67310_1 complement factor B [Homo sapiens] [NCBI NR]
  • gi|297569|emb|CAA51389.1| complement factor B [Homo sapiens] [NCBI NR]
  • gi|25070931|gb|AAN71991.1| B-factor, properdin [Homo sapiens] [NCBI NR]
  • gi|168985957|emb|CAQ07113.1| complement factor B [Homo sapiens] [NCBI NR]
  • gi|168985079|emb|CAQ07483.1| complement factor B [Homo sapiens] [NCBI NR]
  • gi|168984418|emb|CAQ09274.1| complement factor B [Homo sapiens] [NCBI NR]
  • gi|123857994|emb|CAM25864.1| complement factor B [Homo sapiens] [NCBI NR]
  • gi|123263694|emb|CAI41725.2| complement factor B [Homo sapiens] [NCBI NR]
  • complement factor B [HGNC (HUGO)]
  • Complement factor B OS=Homo sapiens GN=CFB PE=1 SV=2 [Swiss-Prot]
  • Splice isoform 1 of P00751 [hmr_yeast5_DM3-1_pombe.fasta]
  • Complement factor B precursor (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2)gi|4261689|gb|AAD13989.1| complement factor B [Homo sapiens]gi|25070931|gb|AAN71991.1| B-factor, properdin [Homo sapiens]gi|625235|pir||B [nrdb_11152004_Chlamydomonas]
  • Complement factor B precursor (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment] [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Complement factor B precursor (Fragment) [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • complement factor B preproprotein [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Complement factor B precursor [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • complement factor B [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • B-factor, properdin [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Complement factor B precursor (Fragment) [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 SPLICE ISOFORM 1 OF COMPLEMENT FACTOR B PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Complement factor B; AltName: Full=C3/C5 convertase; AltName: Full=Properdin factor B; AltName: Full=Glycine-rich beta glycoprotein; Short=GBG; AltName: Full=PBF2; Contains: RecName: Full=Complement factor B Ba fragment; Contains: RecName: F [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CFB Isoform 1 of Complement factor B (Fragment) [human-ipi-250309-contam.fasta]
  • IPI:IPI00921523.1|SWISS-PROT:P00751-1|TREMBL:B0QZQ6|ENSEMBL:ENSP00000388352;ENSP00000389604;ENSP00000391902;ENSP00000401719;ENSP00000411515;ENSP00000413351;ENSP00000413494;ENSP00000414341;ENSP00000414889;ENSP00000416561|REFSEQ:NP_001701|VEGA:OTTHUMP000000 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=CFB Isoform 1 of Complement factor B precursor (Fragment) ENSG00000204359 IPI00218508 IPI00019591 IPI00639937 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CFB Isoform 1 of Complement factor B precursor (Fragment) [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • P00751;B0QZQ6;O15006;Q29944;Q5JP67;Q5ST50;Q96HX6;Q9BTF5;Q9BX92; RecName: Full=Complement factor B; AltName: Full=C3/C5 convertase; AltName: Full=Properdin factor B; AltName: Full=Glycine-rich beta glycoprotein; AltName: Full=PBF2; Contains: RecName: Full=Complement factor B Ba fragment; Contains: RecName: Full=Complement factor B Bb fragment; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Complement factor B OS=Homo sapiens GN=CFB [011711_HMR.fasta]
  • IPI:IPI00921523.1|SWISS-PROT:P00751-1|ENSEMBL:ENSP00000388352;ENSP00000389604;ENSP00000391902;ENSP00000401719;ENSP00000411515;ENSP00000413351;ENSP00000414341;ENSP00000414889;ENSP00000416561|REFSEQ:NP_001701|VEGA:OTTHUMP00000029283;OTTHUMP00000029723;OTTHUMP00000174690;OTTHUMP00000174736;OTTHUMP00000174746;OTTHUMP00000174747;OTTHUMP00000193520;OTTHUMP00000193521;OTTHUMP00000194354;OTTHUMP00000194355 Tax_Id=9606 Gene_Symbol=CFB Isoform 1 of Complement factor B (Fragment) [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=CFB Synonyms=AHUS4|BF|BFD|CFAB|FB|FBI12|FLJ54899|GBG|H2-Bf|PBF2 complement factor B preproprotein [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00921523.1|SWISS-PROT:P00751-1|TREMBL:D2KT84|ENSEMBL:ENSP00000388352;ENSP00000389604;ENSP00000391902;ENSP00000401719;ENSP00000411515;ENSP00000413351;ENSP00000414341;ENSP00000414889;ENSP00000416561|REFSEQ:NP_001701|VEGA:OTTHUMP00000029283;OTTHUMP00000029723;OTTHUMP00000174736;OTTHUMP00000174746;OTTHUMP00000174747;OTTHUMP00000193520;OTTHUMP00000193521;OTTHUMP00000194354;OTTHUMP00000194355 Tax_Id=9606 Gene_Symbol=CFB Isoform 1 of Complement factor B (Fragment) [ipi.HUMAN.20110912.fasta]
  • Complement factor B GN=CFB [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 764 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSNLSPQLC LMPFILGLLS GGVTTTPWSL ARPQGSCSLE GVEIKGGSFR LLQEGQALEY  60
   61 VCPSGFYPYP VQTRTCRSTG SWSTLKTQDQ KTVRKAECRA IHCPRPHDFE NGEYWPRSPY 120
  121 YNVSDEISFH CYDGYTLRGS ANRTCQVNGR WSGQTAICDN GAGYCSNPGI PIGTRKVGSQ 180
  181 YRLEDSVTYH CSRGLTLRGS QRRTCQEGGS WSGTEPSCQD SFMYDTPQEV AEAFLSSLTE 240
  241 TIEGVDAEDG HGPGEQQKRK IVLDPSGSMN IYLVLDGSDS IGASNFTGAK KCLVNLIEKV 300
  301 ASYGVKPRYG LVTYATYPKI WVKVSEADSS NADWVTKQLN EINYEDHKLK SGTNTKKALQ 360
  361 AVYSMMSWPD DVPPEGWNRT RHVIILMTDG LHNMGGDPIT VIDEIRDLLY IGKDRKNPRE 420
  421 DYLDVYVFGV GPLVNQVNIN ALASKKDNEQ HVFKVKDMEN LEDVFYQMID ESQSLSLCGM 480
  481 VWEHRKGTDY HKQPWQAKIS VIRPSKGHES CMGAVVSEYF VLTAAHCFTV DDKEHSIKVS 540
  541 VGGEKRDLEI EVVLFHPNYN INGKKEAGIP EFYDYDVALI KLKNKLKYGQ TIRPICLPCT 600
  601 EGTTRALRLP PTTTCQQQKE ELLPAQDIKA LFVSEEEKKL TRKEVYIKNG DKKGSCERDA 660
  661 QYAPGYDKVK DISEVVTPRF LCTGGVSPYA DPNTCRGDSG GPLIVHKRSR FIQVGVISWG 720
  721 VVDVCKNQKR QKQVPAHARD FHINLFQVLP WLKEKLQDED LGFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle