Protein Overview: ROBO1

General Information:
Name(s) found:	ROBO1 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|49036500\|sp\|Q9Y6N7.1\|ROBO1_HUMAN RecName: Full=Roundabout homolog 1; AltName: Full=H-Robo-1; AltName: Full=Deleted in U twenty twenty; Flags: Precursor [NCBI NR] gi\|4506569\|ref\|NP_002932.1\| roundabout 1 isoform a [Homo sapiens] [NCBI NR] gi\|2804784\|gb\|AAC39575.1\| roundabout 1 [Homo sapiens] [NCBI NR] roundabout, axon guidance receptor, homolog 1 (Drosophila) [HGNC (HUGO)] Roundabout homolog 1 OS=Homo sapiens GN=ROBO1 PE=1 SV=1 [Swiss-Prot] (Q9Y6N7) Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty) [Swiss-Prot] Roundabout 1 [hmr_yeast5_DM3-1_pombe.fasta] roundabout 1 isoform a; roundabout 1; axon guidance receptor [HMR_022704.fasta] roundabout 1 isoform a [Homo sapiens]gi\|49036500\|sp\|Q9Y6N7\|ROB1_HUMAN Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty)gi\|2804784\|gb\|AAC39575.1\| roundabout 1 [Homo sapiens] [nrdb_11152004_Chlamydomonas] Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splice Isoform 1 of Roundabout homolog 1 precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_002941) roundabout 1, isoform a; axon guidance receptor [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] roundabout 1 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] roundabout 1 isoform a; roundabout 1; axon guidance receptor [Homo sapiens] [HumanGallus06162005.fasta] roundabout 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform 1 of Roundabout homolog 1 precursor [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 SPLICE ISOFORM 1 OF ROUNDABOUT HOMOLOG 1 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=ROBO1 Isoform 1 of Roundabout homolog 1 [human-ipi-250309-contam.fasta] IPI:IPI00219798.1\|SWISS-PROT:Q9Y6N7-1\|TREMBL:A6NH24;B4DMJ0\|ENSEMBL:ENSP00000305626\|REFSEQ:NP_002932\|H-INV:HIT000063633\|VEGA:OTTHUMP00000171889 Tax_Id=9606 Gene_Symbol=ROBO1 Isoform 1 of Roundabout homolog 1 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=ROBO1 Isoform 1 of Roundabout homolog 1 precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] roundabout homolog 1 isoform a precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q9Y6N7;Q7Z300;Q9BUS7; RecName: Full=Roundabout homolog 1; AltName: Full=H-Robo-1; AltName: Full=Deleted in U twenty twenty; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform 1 of Roundabout homolog 1 OS=Homo sapiens GN=ROBO1 [011711_HMR.fasta] IPI:IPI00219798.1\|SWISS-PROT:Q9Y6N7-1\|TREMBL:A6NH24;B4DMJ0\|ENSEMBL:ENSP00000305626;ENSP00000420321\|REFSEQ:NP_002932\|H-INV:HIT000063633\|VEGA:OTTHUMP00000171889 Tax_Id=9606 Gene_Symbol=ROBO1 Isoform 1 of Roundabout homolog 1 [ipi.HUMAN.fasta.20100406] GeneSymbol=ROBO1 Synonyms=DUTT1\|FLJ21882\|MGC131599\|MGC133277\|SAX3 roundabout homolog 1 isoform a precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00219798.1\|SWISS-PROT:Q9Y6N7-1\|TREMBL:B4DMJ0\|ENSEMBL:ENSP00000420321\|REFSEQ:NP_002932\|H-INV:HIT000063633\|VEGA:OTTHUMP00000213706 Tax_Id=9606 Gene_Symbol=ROBO1 Isoform 1 of Roundabout homolog 1 [ipi.HUMAN.20110912.fasta] Roundabout homolog 1 GN=ROBO1 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	1651 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKWKHVPFLV MISLLSLSPN HLFLAQLIPD PEDVERGNDH GTPIPTSDND DNSLGYTGSR  60
   61 LRQEDFPPRI VEHPSDLIVS KGEPATLNCK AEGRPTPTIE WYKGGERVET DKDDPRSHRM 120
  121 LLPSGSLFFL RIVHGRKSRP DEGVYVCVAR NYLGEAVSHN ASLEVAILRD DFRQNPSDVM 180
  181 VAVGEPAVME CQPPRGHPEP TISWKKDGSP LDDKDERITI RGGKLMITYT RKSDAGKYVC 240
  241 VGTNMVGERE SEVAELTVLE RPSFVKRPSN LAVTVDDSAE FKCEARGDPV PTVRWRKDDG 300
  301 ELPKSRYEIR DDHTLKIRKV TAGDMGSYTC VAENMVGKAE ASATLTVQEP PHFVVKPRDQ 360
  361 VVALGRTVTF QCEATGNPQP AIFWRREGSQ NLLFSYQPPQ SSSRFSVSQT GDLTITNVQR 420
  421 SDVGYYICQT LNVAGSIITK AYLEVTDVIA DRPPPVIRQG PVNQTVAVDG TFVLSCVATG 480
  481 SPVPTILWRK DGVLVSTQDS RIKQLENGVL QIRYAKLGDT GRYTCIASTP SGEATWSAYI 540
  541 EVQEFGVPVQ PPRPTDPNLI PSAPSKPEVT DVSRNTVTLS WQPNLNSGAT PTSYIIEAFS 600
  601 HASGSSWQTV AENVKTETSA IKGLKPNAIY LFLVRAANAY GISDPSQISD PVKTQDVLPT 660
  661 SQGVDHKQVQ RELGNAVLHL HNPTVLSSSS IEVHWTVDQQ SQYIQGYKIL YRPSGANHGE 720
  721 SDWLVFEVRT PAKNSVVIPD LRKGVNYEIK ARPFFNEFQG ADSEIKFAKT LEEAPSAPPQ 780
  781 GVTVSKNDGN GTAILVSWQP PPEDTQNGMV QEYKVWCLGN ETRYHINKTV DGSTFSVVIP 840
  841 FLVPGIRYSV EVAASTGAGS GVKSEPQFIQ LDAHGNPVSP EDQVSLAQQI SDVVKQPAFI 900
  901 AGIGAACWII LMVFSIWLYR HRKKRNGLTS TYAGIRKVPS FTFTPTVTYQ RGGEAVSSGG 960
  961 RPGLLNISEP AAQPWLADTW PNTGNNHNDC SISCCTAGNG NSDSNLTTYS RPADCIANYN1020
 1021 NQLDNKQTNL MLPESTVYGD VDLSNKINEM KTFNSPNLKD GRFVNPSGQP TPYATTQLIQ1080
 1081 SNLSNNMNNG SGDSGEKHWK PLGQQKQEVA PVQYNIVEQN KLNKDYRAND TVPPTIPYNQ1140
 1141 SYDQNTGGSY NSSDRGSSTS GSQGHKKGAR TPKVPKQGGM NWADLLPPPP AHPPPHSNSE1200
 1201 EYNISVDESY DQEMPCPVPP ARMYLQQDEL EEEEDERGPT PPVRGAASSP AAVSYSHQST1260
 1261 ATLTPSPQEE LQPMLQDCPE ETGHMQHQPD RRRQPVSPPP PPRPISPPHT YGYISGPLVS1320
 1321 DMDTDAPEEE EDEADMEVAK MQTRRLLLRG LEQTPASSVG DLESSVTGSM INGWGSASEE1380
 1381 DNISSGRSSV SSSDGSFFTD ADFAQAVAAA AEYAGLKVAR RQMQDAAGRR HFHASQCPRP1440
 1441 TSPVSTDSNM SAAVMQKTRP AKKLKHQPGH LRRETYTDDL PPPPVPPPAI KSPTAQSKTQ1500
 1501 LEVRPVVVPK LPSMDARTDR SSDRKGSSYK GREVLDGRQV VDMRTNPGDP REAQEQQNDG1560
 1561 KGRGNKAAKR DLPPAKTHLI QEDILPYCRP TFPTSNNPRD PSSSSSMSSR GSGSRQREQA1620
 1621 NVGRRNIAEM QVLGGYERGE DNNEELEETE S

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ROBO1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: