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Protein Overview: UFD1L

General Information:
Name(s) found: UFD1L [HGNC (HUGO)]
Description(s) found:
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  • gi|47678745|emb|CAG30493.1| UFD1L [Homo sapiens] [NCBI NR]
  • gi|4741983|gb|AAD28788.1|AF141201_1 ubiquitin fusion-degradation 1 protein [Homo sapiens] [NCBI NR]
  • gi|29501813|ref|NP_005650.2| ubiquitin fusion degradation 1-like isoform A [Homo sapiens] [NCBI NR]
  • gi|21392363|gb|AAM48288.1| ubiquitin fusion degradation 1-like [Homo sapiens] [NCBI NR]
  • gi|160332310|sp|Q92890.3|UFD1_HUMAN RecName: Full=Ubiquitin fusion degradation protein 1 homolog; Short=UB fusion protein 1 [NCBI NR]
  • gi|13477241|gb|AAH05087.1| Ubiquitin fusion degradation 1 like (yeast) [Homo sapiens] [NCBI NR]
  • gi|12654447|gb|AAH01049.1| Ubiquitin fusion degradation 1 like (yeast) [Homo sapiens] [NCBI NR]
  • gi|12053683|emb|CAC20414.1| ubiquitin fusion degradation 1 protein [Homo sapiens] [NCBI NR]
  • gi|119623443|gb|EAX03038.1| ubiquitin fusion degradation 1 like (yeast), isoform CRA_b [Homo sapiens] [NCBI NR]
  • ubiquitin fusion degradation 1 like (yeast) [HGNC (HUGO)]
  • Ubiquitin fusion degradation protein 1 homolog OS=Homo sapiens GN=UFD1L PE=1 SV=3 [Swiss-Prot]
  • Splice isoform Short of Q92890 Ubiquitin fusion degradation protein 1 homolog [hmr_yeast5_DM3-1_pombe.fasta]
  • ubiquitin fusion degradation 1-like [HMR_022704.fasta]
  • ubiquitin fusion degradation 1-like [Homo sapiens]gi|12654447|gb|AAH01049.1| Ubiquitin fusion degradation 1-like [Homo sapiens]gi|13477241|gb|AAH05087.1| Ubiquitin fusion degradation 1-like [Homo sapiens]gi|21392363|gb|AAM48288.1| ubiquitin fusion degr [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 Splice Isoform Short of Ubiquitin fusion degradation protein 1 homolog [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • ubiquitin fusion degradation 1-like isoform A [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 UbiqUitin fUsion degradation 1-like isoform A [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Tax_Id=9606 UbiqUitin fUsion degradation 1-like [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • ubiquitin fusion degradation 1-like [Homo sapiens] [HumanGallus06162005.fasta]
  • UFD1L [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Ubiquitin fusion degradation protein 1 homolog (UB fusion protein 1) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ubiquitin fusion degradation 1 like (yeast), isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Ubiquitin fusion degradation 1 like (yeast) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ubiquitin fusion degradation 1 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ubiquitin fusion-degradation 1 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform Short of Ubiquitin fusion degradation protein 1 homolog [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 UBIQUITIN FUSION DEGRADATION 1-LIKE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=UFD1L Isoform Short of Ubiquitin fusion degradation protein 1 homolog [human-ipi-250309-contam.fasta]
  • IPI:IPI00218292.2|SWISS-PROT:Q92890-2|TREMBL:Q541A5|ENSEMBL:ENSP00000263202|REFSEQ:NP_005650|H-INV:HIT000273467|VEGA:OTTHUMP00000028899;OTTHUMP00000196377 Tax_Id=9606 Gene_Symbol=UFD1L Isoform Short of Ubiquitin fusion degradation protein 1 homolog [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • ubiquitin fusion degradation protein 1 homolog isoform A [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q92890;Q9Y5N0; RecName: Full=Ubiquitin fusion degradation protein 1 homolog; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform Short of Ubiquitin fusion degradation protein 1 homolog OS=Homo sapiens GN=UFD1L [011711_HMR.fasta]
  • GeneSymbol=UFD1L Synonyms=UFD1 ubiquitin fusion degradation protein 1 homolog isoform A [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00218292.2|SWISS-PROT:Q92890-2|TREMBL:Q541A5|ENSEMBL:ENSP00000263202|REFSEQ:NP_005650|H-INV:HIT000273467|VEGA:OTTHUMP00000196377 Tax_Id=9606 Gene_Symbol=UFD1L Isoform Short of Ubiquitin fusion degradation protein 1 homolog [ipi.HUMAN.20110912.fasta]
  • Ubiquitin fusion degradation protein 1 homolog GN=UFD1L [Doctor+uniprot-HUMAN-120911.fasta]
  • Ubiquitin fusion degradation 1 like (Yeast), isoform CRA_b OS=Homo sapiens GN=ufd1 PE=2 SV=1 [uniprot-human-031015-contam.fasta]
  • Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens GN=UFD1 PE=1 SV=3 [human-uniprot-05July2017-contam-hTTBK1.fasta]
    • Organism: Homo sapiens
    Length: 307 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSFNMFDHP IPRVFQNRFS TQYRCFSVSM LAGPNDRSDV EKGGKIIMPP SALDQLSRLN  60
   61 ITYPMLFKLT NKNSDRMTHC GVLEFVADEG ICYLPHWMMQ NLLLEEGGLV QVESVNLQVA 120
  121 TYSKFQPQSP DFLDITNPKA VLENALRNFA CLTTGDVIAI NYNEKIYELR VMETKPDKAV 180
  181 SIIECDMNVD FDAPLGYKEP ERQVQHEEST EGEADHSGYA GELGFRAFSG SGNRLDGKKK 240
  241 GVEPSPSPIK PGDIKRGIPN YEFKLGKITF IRNSRPLVKK VEEDEAGGRF VAFSGEGQSL 300
  301 RKKGRKP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..222] PSI-BLAST 82.221849 Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites
    2 View Details [223..307] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle