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Protein Overview: ATG7

General Information:
Name(s) found: ATG7 [HGNC (HUGO)]
Description(s) found:
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  • gi|62286592|sp|O95352.1|ATG7_HUMAN RecName: Full=Autophagy-related protein 7; AltName: Full=APG7-like; AltName: Full=Ubiquitin-activating enzyme E1-like protein; Short=hAGP7 [NCBI NR]
  • gi|5453668|ref|NP_006386.1| APG7 autophagy 7-like isoform a [Homo sapiens] [NCBI NR]
  • gi|3820614|gb|AAC69630.1| E1-like protein [Homo sapiens] [NCBI NR]
  • gi|119584497|gb|EAW64093.1| ATG7 autophagy related 7 homolog (S. cerevisiae), isoform CRA_a [Homo sapiens] [NCBI NR]
  • ATG7 autophagy related 7 homolog (S. cerevisiae) [HGNC (HUGO)]
  • Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens GN=ATG7 PE=1 SV=1 [Swiss-Prot]
  • E1-like protein [hmr_yeast5_DM3-1_pombe.fasta]
  • APG7 autophagy 7-like; ubiquitin activating enzyme E1-like protein [HMR_022704.fasta]
  • APG7 autophagy 7-like [Homo sapiens]gi|3820614|gb|AAC69630.1| E1-like protein [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Autophagy protein 7-like (APG7-like) (Ubiquitin activating enzyme E1-like protein) (hAGP7) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Autophagy-related protein 7 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_006395) ubiquitin activating enzyme E1-like protein [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • APG7 autophagy 7-like [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Autophagy protein 7-like [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Tax_Id=9606 E1-like protein [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • APG7 autophagy 7-like; ubiquitin activating enzyme E1-like protein [Homo sapiens] [HumanGallus06162005.fasta]
  • Autophagy-related protein 7 (APG7-like) (Ubiquitin-activating enzyme E1-like protein) (hAGP7) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ATG7 autophagy related 7 homolog (S. cerevisiae), isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • E1-like protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform 1 of Autophagy-related protein 7 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 E1-LIKE PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Autophagy-related protein 7; AltName: Full=APG7-like; AltName: Full=Ubiquitin-activating enzyme E1-like protein; Short=hAGP7 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • APG7 autophagy 7-like isoform a [Homo sapiens] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=ATG7 Isoform 1 of Autophagy-related protein 7 [human-ipi-250309-contam.fasta]
  • IPI:IPI00007404.1|SWISS-PROT:O95352-1|TREMBL:B2RB57;B3KQM6;B4DQK1|ENSEMBL:ENSP00000346437|REFSEQ:NP_006386|H-INV:HIT000068407|VEGA:OTTHUMP00000160157;OTTHUMP00000170233 Tax_Id=9606 Gene_Symbol=ATG7 Isoform 1 of Autophagy-related protein 7 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=ATG7 Isoform 1 of Autophagy-related protein 7 ENSG00000197548 IPI00007404 IPI00479911 IPI00793782 IPI00796939 IPI00797591 IPI00790858 IPI00796315 [drosphohumanreversed.fasta]
  • autophagy-related protein 7 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Autophagy-related protein 7 OS=Homo sapiens GN=ATG7 PE=1 SV=1 [UniProtHuman070710.fasta]
  • O95352;Q7L8L0;Q9BWP2;Q9UFH4; RecName: Full=Autophagy-related protein 7; AltName: Full=APG7-like; AltName: Full=Ubiquitin-activating enzyme E1-like protein; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens GN=ATG7 [011711_HMR.fasta]
  • GeneSymbol=ATG7 Synonyms=APG7-LIKE|APG7L|DKFZp434N0735|GSA7 ubiquitin-like modifier-activating enzyme ATG7 isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00007404.1|SWISS-PROT:O95352-1|TREMBL:B2RB57;B3KQM6;B4DQK1|ENSEMBL:ENSP00000346437|REFSEQ:NP_006386|H-INV:HIT000068407|VEGA:OTTHUMP00000160157 Tax_Id=9606 Gene_Symbol=ATG7 Isoform 1 of Ubiquitin-like modifier-activating enzyme ATG7 [ipi.HUMAN.20110912.fasta]
  • Ubiquitin-like modifier-activating enzyme ATG7 GN=ATG7 [Doctor+uniprot-HUMAN-120911.fasta]
  • Tax_Id=9606 Gene_Symbol=ATG7 Isoform 1 of Ubiquitin-like modifier-activating enzyme ATG7 [human-ipi-270911-contam-BSA.fasta]
    • Organism: Homo sapiens
    Length: 703 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAATGDPGL SKLQFAPFSS ALDVGFWHEL TQKKLNEYRL DEAPKDIKGY YYNGDSAGLP  60
   61 ARLTLEFSAF DMSAPTPARC CPAIGTLYNT NTLESFKTAD KKLLLEQAAN EIWESIKSGT 120
  121 ALENPVLLNK FLLLTFADLK KYHFYYWFCY PALCLPESLP LIQGPVGLDQ RFSLKQIEAL 180
  181 ECAYDNLCQT EGVTALPYFL IKYDENMVLV SLLKHYSDFF QGQRTKITIG VYDPCNLAQY 240
  241 PGWPLRNFLV LAAHRWSSSF QSVEVVCFRD RTMQGARDVA HSIIFEVKLP EMAFSPDCPK 300
  301 AVGWEKNQKG GMGPRMVNLS ECMDPKRLAE SSVDLNLKLM CWRLVPTLDL DKVVSVKCLL 360
  361 LGAGTLGCNV ARTLMGWGVR HITFVDNAKI SYSNPVRQPL YEFEDCLGGG KPKALAAADR 420
  421 LQKIFPGVNA RGFNMSIPMP GHPVNFSSVT LEQARRDVEQ LEQLIESHDV VFLLMDTRES 480
  481 RWLPAVIAAS KRKLVINAAL GFDTFVVMRH GLKKPKQQGA GDLCPNHPVA SADLLGSSLF 540
  541 ANIPGYKLGC YFCNDVVAPG DSTRDRTLDQ QCTVSRPGLA VIAGALAVEL MVSVLQHPEG 600
  601 GYAIASSSDD RMNEPPTSLG LVPHQIRGFL SRFDNVLPVS LAFDKCTACS SKVLDQYERE 660
  661 GFNFLAKVFN SSHSFLEDLT GLTLLHQETQ AAEIWDMSDD ETI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..164] MSA 1.039967 View MSA. No confident structure predictions are available.
    2 View Details [165..256] deduced N/A No confident structure predictions are available.
    3 View Details [257..323] MSA 2.197993 View MSA. No confident structure predictions are available.
    4 View Details [324..639] PSI-BLAST 62.39794 No description for 2nvuB was found.
    5 View Details [640..703] MSA 3.105993 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle