Protein Overview: gi|109945583

General Information:
Name(s) found:	gi\|109945583 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|109945583\|dbj\|BAE96971.1\| DNA topoisomerase IIbeta [Rattus norvegicus] [NCBI NR] DNA topoisomerase IIbeta [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=LOC361100 DNA topoisomerase 2 (Fragment) [rat-ipi-250309-contam.fasta] DNA topoisomerase 2 OS=Rattus norvegicus GN=LOC361100 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1614 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] chromosome [IEA]
Biological Process:	DNA topological change [IEA]
Molecular Function:	DNA binding [IEA] ATP binding [IEA] DNA topoisomerase (ATP-hydrolyzing) activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKSSLAGVD GALTWVNNAA KKEELETANK NDSSKKLSVE RVYQKKTQLE HILLRPDTYI  60
   61 GSVEPLTQLM WVYDEDVGMN CREVTFVPGL YKIFDEILVN AADNKQRDKN MTCIKVSIDP 120
  121 ESNIISIWNN GKGIPVVEHK VEKVYVPALI FGQLLTSSNY DDDEKKVTGG RNGYGAKLCN 180
  181 IFSTKFTVET ACKEYKHSFK QTWMNNMMKT SEAKIKHFDG EDYTCITFQP DLAKFKMEKL 240
  241 DKDIVALMTR RAYDLAGSCK GVKVMFNGKK LPVNGFRSYV DLYVKDKLDE TGVALKVIHE 300
  301 LANERWDVCL TLSEKGFQQI SFVNSIATTK GGRHVDYVVD QVVGKLIEVV KKKNKAGVSV 360
  361 KPFQVKNHIW VFINCLIENP TFDSQTKENM TLQPKSFGSK CQLSEKFFKA ASNCGIVESI 420
  421 LNWVKFKAQT QLNKKCSSVK YSKIKGIPKL DDANDAGGKH SLECTLILTE GDSAKSLAVS 480
  481 GLGVIGRDRY GVFPLRGKIL NAREASHKQI MENAEINNII KIVGLQYKKS YDDAESLKTL 540
  541 RYGKIMIMTD QDQDGSHIKG LLINFIHHNW PSLLKHGFLE EFITPIVKAS KNKQELSFYS 600
  601 IPEFDEWEKH IENQKAWKIK YYKGLGTSTA KEAKEYFADM ERHRILFRYA GPEDDAAITL 660
  661 AFSKKKIDDR KEWLTNFMED RRQRRLHGLP EQFLYGTATK HLTYNDFINK ELILFSNSDN 720
  721 ERSIPSLVDG FKPGQRKVLF TCFKRNDKRE VKVAQLAGSV AEMSAYHHGE QALMMTIVNL 780
  781 AQNFVGSNNI NLLQPIGQFG TRLHGGKDAA SPRYIFTMLS SLARLLFPAV DDNLLKFLYD 840
  841 DNQRVEPEWY IPIIPMVLIN GAEGIGTGWA CKLPNYDARE IVNNVRRMLE GLDPHPMLPN 900
  901 YKNFKGTIQE LGQNQYAVSG EIFVVDRNTV EITELPVRTW TQVYKEQVLE PMLNGTDKTP 960
  961 ALISDYKEYH TDTTVKFVVK MTEEKLAQAE AAGLHKVFKL QTTLTCNSMV LFDHMGCLKK1020
 1021 YETVQDILKE FFDLRLSYYG LRKEWLVGML GAESTKLNNQ ARFILEKIQG KITIENRSKK1080
 1081 DLIQMLVQRG YESDPVKAWK EAQEKAAEEE DAQNPHDDSS SDSGTPSGPD FNYILNMSLW1140
 1141 SLTKEKVEEL IKQRDTKGRE VNDLKRKSPS DLWKEDLAAF VEELDKVEAQ EREDILAGMS1200
 1201 GKAVKGKVGK AKVKKLQLEE TMPSPYGRRI VPEITAMKAD ASRKLLKKKK GDPDTTVVKV1260
 1261 EFDEEFSGTP AEGTGEETLT PSAPVNKGPK PKREKKEPGT RVRKTPASTG KPNTKKVKKR1320
 1321 NPWSDDESKS ESDLEEAEPV VIPRDSLLRR AAAERPKYTF DFSEEEEDDA DDDDDNNDLE1380
 1381 ELKVKASPIT NDGEDEFVPS DGIDKDEYAF SPGKSKATPE KSSHDKKSQD FGNLFSFPSY1440
 1441 SQKSEDDSAK FDSNEEDTTS VFAPSFGLKQ TDKVPSQTVA AKKGKAPSDA AAPKAKRAPR1500
 1501 QRKVVEPANS DSDSELGNIP KKTAAPKGKG RGAKKRKASG SENEGDYNPG RKPSKTASKK1560
 1561 PKKTSFDQDS DVDIFPSDFT SEPPALPRTG RARKEVKYFA ESDEEEDVDF AMFN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.71

Protein Overview: gi|109945583

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: