Protein Overview: GBF1

General Information:
Name(s) found:	GBF1 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|55957157\|emb\|CAI12515.1\| golgi-specific brefeldin A resistance factor 1 [Homo sapiens] [NCBI NR] gi\|55662967\|emb\|CAH72761.1\| golgi-specific brefeldin A resistance factor 1 [Homo sapiens] [NCBI NR] gi\|55662264\|emb\|CAH71625.1\| golgi-specific brefeldin A resistance factor 1 [Homo sapiens] [NCBI NR] gi\|4758416\|ref\|NP_004184.1\| golgi-specific brefeldin A resistant guanine nucleotide exchange factor 1 [Homo sapiens] [NCBI NR] gi\|4321980\|gb\|AAD15903.1\| sec7 domain family member [Homo sapiens] [NCBI NR] gi\|13124260\|sp\|Q92538.2\|GBF1_HUMAN RecName: Full=Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; Short=BFA-resistant GEF 1 [NCBI NR] gi\|119570092\|gb\|EAW49707.1\| golgi-specific brefeldin A resistance factor 1 [Homo sapiens] [NCBI NR] golgi brefeldin A resistant guanine nucleotide exchange factor 1 [HGNC (HUGO)] Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 PE=1 SV=2 [Swiss-Prot] Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [hmr_yeast5_DM3-1_pombe.fasta] golgi-specific brefeldin A resistance factor 1; golgi-specific Brefeldin A-resistance factor; golgi-specific brefeldin A-resistance factor 1 [HMR_022704.fasta] golgi-specific brefeldin A resistance factor 1 [Homo sapiens]gi\|55662967\|emb\|CAH72761.1\| OTTHUMP00000059184 [Homo sapiens]gi\|55662264\|emb\|CAH71625.1\| OTTHUMP00000059184 [Homo sapiens]gi\|13124260\|sp\|Q92538\|GBF1_HUMAN Golgi-specific brefeldin A-resistanc [nrdb_11152004_Chlamydomonas] Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_004193) golgi-specific brefeldin A resistance factor 1; golgi-specific Brefeldin A-resistance factor; golgi-specific brefeldin A-resistance factor 1 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] golgi-specific brefeldin A resistance factor 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] golgi-specific brefeldin A resistance factor 1; golgi-specific Brefeldin A-resistance factor; golgi-specific brefeldin A-resistance factor 1 [Homo sapiens] [HumanGallus06162005.fasta] sec7 domain family member [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] golgi-specific brefeldin A resistant guanine nucleotide exchange factor 1 [Homo sapiens] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [human-ipi-250309-contam.fasta] golgi brefeldin A resistant guanine nucleotide exchange factor 1 [Homo sapiens] [NCBI-RefSeq_Human_na_02-15-2010_reversed.fasta] IPI:IPI00021954.1\|SWISS-PROT:Q92538\|TREMBL:Q05BW6;Q149P0;Q149P1;Q504U7\|ENSEMBL:ENSP00000359000\|REFSEQ:NP_004184\|H-INV:HIT000065621\|VEGA:OTTHUMP00000020365 Tax_Id=9606 Gene_Symbol=GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange facto [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 ENSG00000107862 IPI00021954 [drosphohumanreversed.fasta] Q92538;Q5VXX3;Q96CK6;Q96HZ3;Q9H473; RecName: Full=Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens GN=GBF1 [011711_HMR.fasta] IPI:IPI00021954.1\|SWISS-PROT:Q92538\|TREMBL:Q05BW6;Q149P0;Q149P1;Q504U7\|ENSEMBL:ENSP00000359000\|REFSEQ:NP_004184\|H-INV:HIT000065621\|VEGA:OTTHUMP00000020365 Tax_Id=9606 Gene_Symbol=GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [ipi.HUMAN.fasta.20100406] GeneSymbol=GBF1 Synonyms=ARF1GEF\|FLJ21263\|FLJ21500\|KIAA0248\|MGC134877\|MGC134878 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00021954.1\|SWISS-PROT:Q92538\|TREMBL:Q149P1\|ENSEMBL:ENSP00000359000\|REFSEQ:NP_004184\|H-INV:HIT000065621\|VEGA:OTTHUMP00000020365 Tax_Id=9606 Gene_Symbol=GBF1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 [ipi.HUMAN.20110912.fasta] Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 GN=GBF1 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	1859 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDKNIYIIQ GEINIVVGAI KRNARWSTHT PLDEERDPLL HSFGHLKEVL NSITELSEIE  60
   61 PNVFLRPFLE VIRSEDTTGP ITGLALTSVN KFLSYALIDP THEGTAEGME NMADAVTHAR 120
  121 FVGTDPASDE VVLMKILQVL RTLLLTPVGA HLTNESVCEI MQSCFRICFE MRLSELLRKS 180
  181 AEHTLVDMVQ LLFTRLPQFK EEPKNYVGTN MKKLKMRAGG MSDSSKWKKQ KRSPRPPRHM 240
  241 TKVTPGSELP TPNGTTLSSN LTGGMPFIDV PTPISSASSE AASAVVSPST DSGLEFSSQT 300
  301 TSKEDLTDLE QPGSPGYSTA TEPGSSELGV PEQPDLQEGT HVEKSQSASV ESIPEVLEEC 360
  361 TSPADHSDSA SVHDMDYVNP RGVRFTQSSQ KEGTALVPYG LPCIRELFRF LISLTNPHDR 420
  421 HNSEVMIHMG LHLLTVALES APVAQCQTLL GLIKDEMCRH LFQLLSIERL NLYAASLRVC 480
  481 FLLFESMREH LKFQMEMYIK KLMEIITVEN PKMPYEMKEM ALEAIVQLWR IPSFVTELYI 540
  541 NYDCDYYCSN LFEELTKLLS KNAFPVSGQL YTTHLLSLDA LLTVIDSTEA HCQAKVLNSL 600
  601 TQQEKKETAR PSCEIVDGTR EASNTERTAS DGKAVGMASD IPGLHLPGGG RLPPEHGKSG 660
  661 CSDLEEAVDS GADKKFARKP PRFSCLLPDP RELIEIKNKK KLLITGTEQF NQKPKKGIQF 720
  721 LQEKGLLTIP MDNTEVAQWL RENPRLDKKM IGEFVSDRKN IDLLESFVST FSFQGLRLDE 780
  781 ALRLYLEAFR LPGEAPVIQR LLEAFTERWM NCNGSPFANS DACFSLAYAV IMLNTDQHNH 840
  841 NVRKQNAPMT LEEFRKNLKG VNGGKDFEQD ILEDMYHAIK NEEIVMPEEQ TGLVRENYVW 900
  901 NVLLHRGATP EGIFLRVPTA SYDLDLFTMT WGPTIAALSY VFDKSLEETI IQKAISGFRK 960
  961 CAMISAHYGL SDVFDNLIIS LCKFTALSSE SIENLPSVFG SNPKAHIAAK TVFHLAHRHG1020
 1021 DILREGWKNI MEAMLQLFRA QLLPKAMIEV EDFVDPNGKI SLQREETPSN RGESTVLSFV1080
 1081 SWLTLSGPEQ SSVRGPSTEN QEAKRVALEC IKQCDPEKMI TESKFLQLES LQELMKALVS1140
 1141 VTPDEETYDE EDAAFCLEML LRIVLENRDR VGCVWQTVRD HLYHLCVQAQ DFCFLVERAV1200
 1201 VGLLRLAIRL LRREEISAQV LLSLRILLLM KPSVLSRVSH QVAYGLHELL KTNAANIHSG1260
 1261 DDWATLFTLL ECIGSGVKPP AALQATARAD APDAGAQSDS ELPSYHQNDV SLDRGYTSDS1320
 1321 EVYTDHGRPG KIHRSATDAD VVNSGWLVVG KDDVDNSKPG PSRPGPSPLI NQYSLTVGLD1380
 1381 LGPHDTKSLL KCVESLSFIV RDAAHITPDN FELCVKTLRI FVEASLNGGC KSQEKRGKSH1440
 1441 KYDSKGNRFK KKSKEGSMLR RPRTSSQHAS RGGQSDDDED EGVPASYHTV SLQVSQDLLD1500
 1501 LMHTLHTRAA SIYSSWAEEQ RHLETGGQKI EADSRTLWAH CWCPLLQGIA CLCCDARRQV1560
 1561 RMQALTYLQR ALLVHDLQKL DALEWESCFN KVLFPLLTKL LENISPADVG GMEETRMRAS1620
 1621 TLLSKVFLQH LSPLLSLSTF AALWLTILDF MDKYMHAGSS DLLSEAIPES LKNMLLVMDT1680
 1681 AEIFHSADAR GGGPSALWEI TWERIDCFLP HLRDELFKQT VIQDPMPMEP QGQKPLASAH1740
 1741 LTSAAGDTRT PGHPPPPEIP SELGACDFEK PESPRAASSS SPGSPVASSP SRLSPTPDGP1800
 1801 PPLAQPPLIL QPLASPLQVG VPPMTLPIIL NPALIEATSP VPLLATPRPT DPIPTSEVN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	Sample pIC145 from april 2005	Okada, M., et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.47

Protein Overview: GBF1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: