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Protein Overview: MTR

General Information:
Name(s) found: MTR [HGNC (HUGO)]
Description(s) found:
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  • gi|55664707|emb|CAH73198.1| 5-methyltetrahydrofolate-homocysteine methyltransferase [Homo sapiens] [NCBI NR]
  • gi|55664391|emb|CAH70983.1| 5-methyltetrahydrofolate-homocysteine methyltransferase [Homo sapiens] [NCBI NR]
  • gi|2842762|sp|Q99707.2|METH_HUMAN RecName: Full=Methionine synthase; AltName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase; AltName: Full=Vitamin-B12 dependent methionine synthase; Short=MS [NCBI NR]
  • gi|223460110|gb|AAI36441.1| 5-methyltetrahydrofolate-homocysteine methyltransferase [Homo sapiens] [NCBI NR]
  • gi|1923221|gb|AAC51188.1| 5-methyltetrahydrofolate-homocysteine methyltransferase [Homo sapiens] [NCBI NR]
  • gi|1763269|gb|AAB39704.1| methionine synthase [Homo sapiens] [NCBI NR]
  • gi|169790923|ref|NP_000245.2| 5-methyltetrahydrofolate-homocysteine methyltransferase [Homo sapiens] [NCBI NR]
  • gi|119590472|gb|EAW70066.1| 5-methyltetrahydrofolate-homocysteine methyltransferase, isoform CRA_a [Homo sapiens] [NCBI NR]
  • 5-methyltetrahydrofolate-homocysteine methyltransferase [HGNC (HUGO)]
  • Methionine synthase OS=Homo sapiens GN=MTR PE=1 SV=2 [Swiss-Prot]
  • 5-methyltetrahydrofolate--homocysteine methyltransferase [hmr_yeast5_DM3-1_pombe.fasta]
  • OTTHUMP00000046536 [Homo sapiens]gi|55664391|emb|CAH70983.1| 5-methyltetrahydrofolate-homocysteine methyltransferase [Homo sapiens]gi|2842762|sp|Q99707|METH_HUMAN Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) (Methionine [nrdb_11152004_Chlamydomonas]
  • Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Methionine synthase [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • methionine synthase [Homo sapiens] [NCBI-RefSeq_human_na_05-03-2007_con_reversed.fasta]
  • 5-methyltetrahydrofolate-homocysteine methyltransferase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) (Vitamin-B12 dependent methionine synthase) (MS) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • 5-methyltetrahydrofolate-homocysteine methyltransferase, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • RecName: Full=Methionine synthase; AltName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase; AltName: Full=Vitamin-B12 dependent methionine synthase; Short=MS [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=MTR Methionine synthase [human-ipi-250309-contam.fasta]
  • IPI:IPI00743284.2|SWISS-PROT:Q99707|TREMBL:B7ZLW7;B7ZLW8;B9EGF7|ENSEMBL:ENSP00000355536|REFSEQ:NP_000245|H-INV:HIT000221209|VEGA:OTTHUMP00000037964 Tax_Id=9606 Gene_Symbol=MTR Methionine synthase [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Q99707;A1L4N8;A9Z1W4;B9EGF7;Q99713;Q99723; RecName: Full=Methionine synthase; AltName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase; AltName: Full=Vitamin-B12 dependent methionine synthase; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Methionine synthase OS=Homo sapiens GN=MTR [011711_HMR.fasta]
  • IPI:IPI00743284.2|SWISS-PROT:Q99707|TREMBL:B7ZLW7;B7ZLW8|ENSEMBL:ENSP00000355536|REFSEQ:NP_000245|H-INV:HIT000221209|VEGA:OTTHUMP00000037964 Tax_Id=9606 Gene_Symbol=MTR Methionine synthase [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=MTR Synonyms=FLJ33168|FLJ43216|FLJ45386|MS|cblG methionine synthase [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00743284.2|SWISS-PROT:Q99707|TREMBL:B7ZLW8|ENSEMBL:ENSP00000355536|REFSEQ:NP_000245|H-INV:HIT000221209|VEGA:OTTHUMP00000037964 Tax_Id=9606 Gene_Symbol=MTR Methionine synthase [ipi.HUMAN.20110912.fasta]
  • Methionine synthase GN=MTR [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 1265 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPALQDLSQ PEGLKKTLRD EINAILQKRI MVLDGGMGTM IQREKLNEEH FRGQEFKDHA  60
   61 RPLKGNNDIL SITQPDVIYQ IHKEYLLAGA DIIETNTFSS TSIAQADYGL EHLAYRMNMC 120
  121 SAGVARKAAE EVTLQTGIKR FVAGALGPTN KTLSVSPSVE RPDYRNITFD ELVEAYQEQA 180
  181 KGLLDGGVDI LLIETIFDTA NAKAALFALQ NLFEEKYAPR PIFISGTIVD KSGRTLSGQT 240
  241 GEGFVISVSH GEPLCIGLNC ALGAAEMRPF IEIIGKCTTA YVLCYPNAGL PNTFGDYDET 300
  301 PSMMAKHLKD FAMDGLVNIV GGCCGSTPDH IREIAEAVKN CKPRVPPATA FEGHMLLSGL 360
  361 EPFRIGPYTN FVNIGERCNV AGSRKFAKLI MAGNYEEALC VAKVQVEMGA QVLDVNMDDG 420
  421 MLDGPSAMTR FCNLIASEPD IAKVPLCIDS SNFAVIEAGL KCCQGKCIVN SISLKEGEDD 480
  481 FLEKARKIKK YGAAMVVMAF DEEGQATETD TKIRVCTRAY HLLVKKLGFN PNDIIFDPNI 540
  541 LTIGTGMEEH NLYAINFIHA TKVIKETLPG ARISGGLSNL SFSFRGMEAI REAMHGVFLY 600
  601 HAIKSGMDMG IVNAGNLPVY DDIHKELLQL CEDLIWNKDP EATEKLLRYA QTQGTGGKKV 660
  661 IQTDEWRNGP VEERLEYALV KGIEKHIIED TEEARLNQKK YPRPLNIIEG PLMNGMKIVG 720
  721 DLFGAGKMFL PQVIKSARVM KKAVGHLIPF MEKEREETRV LNGTVEEEDP YQGTIVLATV 780
  781 KGDVHDIGKN IVGVVLGCNN FRVIDLGVMT PCDKILKAAL DHKADIIGLS GLITPSLDEM 840
  841 IFVAKEMERL AIRIPLLIGG ATTSKTHTAV KIAPRYSAPV IHVLDASKSV VVCSQLLDEN 900
  901 LKDEYFEEIM EEYEDIRQDH YESLKERRYL PLSQARKSGF QMDWLSEPHP VKPTFIGTQV 960
  961 FEDYDLQKLV DYIDWKPFFD VWQLRGKYPN RGFPKIFNDK TVGGEARKVY DDAHNMLNTL1020
 1021 ISQKKLRARG VVGFWPAQSI QDDIHLYAEA AVPQAAEPIA TFYGLRQQAE KDSASTEPYY1080
 1081 CLSDFIAPLH SGIRDYLGLF AVACFGVEEL SKAYEDDGDD YSSIMVKALG DRLAEAFAEE1140
 1141 LHERVRRELW AYCGSEQLDV ADLRRLRYKG IRPAPGYPSQ PDHTEKLTMW RLADIEQSTG1200
 1201 IRLTESLAMA PASAVSGLYF SNLKSKYFAV GKISKDQVED YALRKNISVA EVEKWLGPIL1260
 1261 GYDTD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle