Protein Overview: COG2

General Information:
Name(s) found:	COG2 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|6678676\|ref\|NP_031383.1\| component of oligomeric golgi complex 2 isoform 1 [Homo sapiens] [NCBI NR] gi\|575654\|emb\|CAA84427.1\| Cog2 protein [Homo sapiens] [NCBI NR] gi\|55958307\|emb\|CAI15358.1\| component of oligomeric golgi complex 2 [Homo sapiens] [NCBI NR] gi\|2498512\|sp\|Q14746.1\|COG2_HUMAN RecName: Full=Conserved oligomeric Golgi complex subunit 2; Short=COG complex subunit 2; AltName: Full=Component of oligomeric Golgi complex 2; AltName: Full=Low density lipoprotein receptor defect C-complementing protein [NCBI NR] gi\|189069221\|dbj\|BAG35559.1\| unnamed protein product [Homo sapiens] [NCBI NR] gi\|15928996\|gb\|AAH14960.1\| Component of oligomeric golgi complex 2 [Homo sapiens] [NCBI NR] gi\|119590321\|gb\|EAW69915.1\| component of oligomeric golgi complex 2, isoform CRA_a [Homo sapiens] [NCBI NR] pir\|\|A53542 brefeldin A-sensitive Golgi protein LDLC - human [NCBI NR] component of oligomeric golgi complex 2 [HGNC (HUGO)] Conserved oligomeric Golgi complex subunit 2 OS=Homo sapiens GN=COG2 PE=1 SV=1 [Swiss-Prot] Conserved oligomeric Golgi complex component 2 [hmr_yeast5_DM3-1_pombe.fasta] component of oligomeric golgi complex 2; brefeldin A-sensitive, peripheral Golgi protein; low density lipoprotein receptor defect C complementing; conserved oligomeric Golgi complex protein 2 [HMR_022704.fasta] component of oligomeric golgi complex 2; brefeldin A-sensitive, peripheral Golgi protein; conserved oligomeric Golgi complex protein 2; low density lipoprotein receptor defect C complementing [Human2242005.fasta] component of oligomeric golgi complex 2 [Homo sapiens]gi\|15928996\|gb\|AAH14960.1\| Component of oligomeric golgi complex 2 [Homo sapiens]gi\|2498512\|sp\|Q14746\|COG2_HUMAN Conserved oligomeric Golgi complex component 2 (Low density lipoprotein receptor defec [nrdb_11152004_Chlamydomonas] Conserved oligomeric Golgi complex component 2 (Low density lipoprotein receptor defect C-complementing protein) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Conserved oligomeric Golgi complex component 2 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_007357) component of oligomeric golgi complex 2; brefeldin A-sensitive, peripheral Golgi protein; conserved oligomeric Golgi complex protein 2; low density lipoprotein receptor defect C complementing [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] component of oligomeric golgi complex 2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] component of oligomeric golgi complex 2; brefeldin A-sensitive, peripheral Golgi protein; conserved oligomeric Golgi complex protein 2; low density lipoprotein receptor defect C complementing [Homo sapiens] [HumanGallus06162005.fasta] component of oligomeric golgi complex 2; brefeldin A-sensitive, peripheral Golgi protein; low density lipoprotein receptor defect C complementing; conserved oligomeric Golgi complex protein 2 [Homo sapiens] [human-NCBI-042104-rand.fasta] Conserved oligomeric Golgi complex subunit 2 (COG complex subunit 2) (Component of oligomeric golgi complex 2) (Low density lipoprotein receptor defect C-complementing protein) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] component of oligomeric golgi complex 2, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Component of oligomeric golgi complex 2 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Cog2 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] component of oligomeric golgi complex 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=COG2 Conserved oligomeric Golgi complex subunit 2 [human-ipi-250309-contam.fasta] IPI:IPI00000057.1\|SWISS-PROT:Q14746\|TREMBL:B1ALW7;B7Z2Y2;B7Z819\|ENSEMBL:ENSP00000355629\|REFSEQ:NP_031383\|H-INV:HIT000036923\|VEGA:OTTHUMP00000035875 Tax_Id=9606 Gene_Symbol=COG2 Conserved oligomeric Golgi complex subunit 2 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=COG2 Conserved oligomeric Golgi complex component 2 ENSG00000135775 IPI00643424 IPI00000057 [drosphohumanreversed.fasta] Tax_Id=9606 Gene_Symbol=COG2 Conserved oligomeric Golgi complex component 2 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] conserved oligomeric Golgi complex subunit 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q14746; RecName: Full=Conserved oligomeric Golgi complex subunit 2; AltName: Full=Component of oligomeric Golgi complex 2; AltName: Full=Low density lipoprotein receptor defect C-complementing protein; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Conserved oligomeric Golgi complex subunit 2 OS=Homo sapiens GN=COG2 [011711_HMR.fasta] GeneSymbol=COG2 Synonyms=LDLC conserved oligomeric Golgi complex subunit 2 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00000057.1\|SWISS-PROT:Q14746\|TREMBL:B1ALW7\|ENSEMBL:ENSP00000355629\|REFSEQ:NP_031383\|H-INV:HIT000036923\|VEGA:OTTHUMP00000035875 Tax_Id=9606 Gene_Symbol=COG2 Conserved oligomeric Golgi complex subunit 2 [ipi.HUMAN.20110912.fasta] Conserved oligomeric Golgi complex subunit 2 GN=COG2 [Doctor+uniprot-HUMAN-120911.fasta] Component of oligomeric golgi complex 2, isoform CRA_a OS=Homo sapiens GN=COG2 PE=2 SV=1 [uniprot-human-031015-contam.fasta]
Organism:	Homo sapiens
Length:	738 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKSRMNLPK GPDTLCFDKD EFMKEDFDVD HFVSDCRKRV QLEELRDDLE LYYKLLKTAM  60
   61 VELINKDYAD FVNLSTNLVG MDKALNQLSV PLGQLREEVL SLRSSVSEGI RAVDERMSKQ 120
  121 EDIRKKKMCV LRLIQVIRSV EKIEKILNSQ SSKETSALEA SSPLLTGQIL ERIATEFNQL 180
  181 QFHAVQSKGM PLLDKVRPRI AGITAMLQQS LEGLLLEGLQ TSDVDIIRHC LRTYATIDKT 240
  241 RDAEALVGQV LVKPYIDEVI IEQFVESHPN GLQVMYNKLL EFVPHHCRLL REVTGGAISS 300
  301 EKGNTVPGYD FLVNSVWPQI VQGLEEKLPS LFNPGNPDAF HEKYTISMDF VRRLERQCGS 360
  361 QASVKRLRAH PAYHSFNKKW NLPVYFQIRF REIAGSLEAA LTDVLEDAPA ESPYCLLASH 420
  421 RTWSSLRRCW SDEMFLPLLV HRLWRLTLQI LARYSVFVNE LSLRPISNES PKEIKKPLVT 480
  481 GSKEPSITQG NTEDQGSGPS ETKPVVSISR TQLVYVVADL DKLQEQLPEL LEIIKPKLEM 540
  541 IGFKNFSSIS AALEDSQSSF SACVPSLSSK IIQDLSDSCF GFLKSALEVP RLYRRTNKEV 600
  601 PTTASSYVDS ALKPLFQLQS GHKDKLKQAI IQQWLEGTLS ESTHKYYETV SDVLNSVKKM 660
  661 EESLKRLKQA RKTTPANPVG PSGGMSDDDK IRLQLALDVE YLGEQIQKLG LQASDIKSFS 720
  721 ALAELVAAAK DQATAEQP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..23]	MSA	3.107996	View MSA. No confident structure predictions are available.
2	View Details	[24..241]	PSI-BLAST	28.045757	No description for 2jqqA was found.
3	View Details	[242..487]	deduced	N/A	No confident structure predictions are available.
4	View Details	[488..670]	MSA	1.025994	View MSA. No confident structure predictions are available.
5	View Details	[671..738]	deduced	N/A	No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: COG2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: