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Protein Overview: CKS1B

General Information:
Name(s) found: CKS1B [HGNC (HUGO)]
Description(s) found:
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  • gi|6729910|pdb|1BUH|B Chain B, Crystal Structure Of The Human Cdk2 Kinase Complex With Cell Cycle-Regulatory Protein Ckshs1 [NCBI NR]
  • gi|55960118|emb|CAI13256.1| CDC28 protein kinase regulatory subunit 1B [Homo sapiens] [NCBI NR]
  • gi|47125427|gb|AAH70320.1| CDC28 protein kinase regulatory subunit 1B [Homo sapiens] [NCBI NR]
  • gi|47125424|gb|AAH70319.1| CDC28 protein kinase regulatory subunit 1B [Homo sapiens] [NCBI NR]
  • gi|46577579|sp|P61024.1|CKS1_HUMAN RecName: Full=Cyclin-dependent kinases regulatory subunit 1; Short=CKS-1 [NCBI NR]
  • gi|4502857|ref|NP_001817.1| CDC28 protein kinase 1B [Homo sapiens] [NCBI NR]
  • gi|30583231|gb|AAP35860.1| CDC28 protein kinase regulatory subunit 1B [Homo sapiens] [NCBI NR]
  • gi|29977|emb|CAA38702.1| Cks1 protein homologue [Homo sapiens] [NCBI NR]
  • gi|189053090|dbj|BAG34712.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|15990489|gb|AAH15629.1| CDC28 protein kinase regulatory subunit 1B [Homo sapiens] [NCBI NR]
  • gi|1421475|pdb|1DKT|B Chain B, Ckshs1: Human Cyclin Dependent Kinase Subunit, Type 1 Complex With Metavanadate [NCBI NR]
  • gi|1421474|pdb|1DKT|A Chain A, Ckshs1: Human Cyclin Dependent Kinase Subunit, Type 1 Complex With Metavanadate [NCBI NR]
  • gi|1421473|pdb|1DKS|B Chain B, Ckshs1: Human Cyclin Dependent Kinase Subunit, Type 1 In Complex With Phosphate [NCBI NR]
  • gi|1421472|pdb|1DKS|A Chain A, Ckshs1: Human Cyclin Dependent Kinase Subunit, Type 1 In Complex With Phosphate [NCBI NR]
  • gi|14043535|gb|AAH07751.1| CDC28 protein kinase regulatory subunit 1B [Homo sapiens] [NCBI NR]
  • gi|12751121|gb|AAK07553.1|AF279897_1 PNAS-143 [Homo sapiens] [NCBI NR]
  • gi|12751047|gb|AAK07518.1|AF274941_1 PNAS-16 [Homo sapiens] [NCBI NR]
  • gi|119573549|gb|EAW53164.1| CDC28 protein kinase regulatory subunit 1B, isoform CRA_b [Homo sapiens] [NCBI NR]
  • pir||A36670 cell division control protein CKS1 - human [NCBI NR]
  • CDC28 protein kinase regulatory subunit 1B [HGNC (HUGO)]
  • Cyclin-dependent kinases regulatory subunit 1 OS=Homo sapiens GN=CKS1B PE=1 SV=1 [Swiss-Prot]
  • Cyclin-dependent kinases regulatory subunit 1 [hmr_yeast5_DM3-1_pombe.fasta]
  • CDC28 protein kinase 1B; CDC2-associated protein CKS1; cell division control protein CKS1; NB4 apoptosis/differentiation related protein; PNAS-143; CDC28 protein kinase 1 [HMR_022704.fasta]
  • CDC28 protein kinase 1B; CDC28 protein kinase 1; CDC2-associated protein CKS1; cell division control protein CKS1; NB4 apoptosis/differentiation related protein; PNAS-143 [Human2242005.fasta]
  • CDC28 protein kinase 1b [Mus musculus]gi|8393135|ref|NP_058600.1| CDC28 protein kinase 1b [Mus musculus]gi|4502857|ref|NP_001817.1| CDC28 protein kinase 1B [Homo sapiens]gi|30583231|gb|AAP35860.1| CDC28 protein kinase regulatory subunit 1B [Homo sapien [nrdb_11152004_Chlamydomonas]
  • Cyclin-dependent kinases regulatory subunit 1 (CKS-1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Cyclin-dependent kinases regulatory subunit 1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001826) CDC28 protein kinase 1; CDC2-associated protein CKS1; cell division control protein CKS1; NB4 apoptosis/differentiation related protein; PNAS-143 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • CDC28 protein kinase 1B [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • CDC28 protein kinase 1B; CDC28 protein kinase 1; CDC2-associated protein CKS1; cell division control protein CKS1; NB4 apoptosis/differentiation related protein; PNAS-143 [Homo sapiens] [HumanGallus06162005.fasta]
  • CDC28 protein kinase 1B; CDC2-associated protein CKS1; cell division control protein CKS1; NB4 apoptosis/differentiation related protein; PNAS-143; CDC28 protein kinase 1 [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Chain B, Crystal Structure Of The Human Cdk2 Kinase Complex With Cell Cycle-Regulatory Protein Ckshs1 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain B, Ckshs1: Human Cyclin Dependent Kinase Subunit, Type 1 Complex With Metavanadate [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain A, Ckshs1: Human Cyclin Dependent Kinase Subunit, Type 1 Complex With Metavanadate [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain B, Ckshs1: Human Cyclin Dependent Kinase Subunit, Type 1 In Complex With Phosphate [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Chain A, Ckshs1: Human Cyclin Dependent Kinase Subunit, Type 1 In Complex With Phosphate [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • CDC28 protein kinase regulatory subunit 1B [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • CDC28 protein kinase regulatory subunit 1B, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Cks1 protein homologue [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • PNAS-143 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • PNAS-16 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CKS1B Cyclin-dependent kinases regulatory subunit 1 [human-ipi-250309-contam.fasta]
  • IPI:IPI00015104.1|SWISS-PROT:P61024|TREMBL:Q5T178|ENSEMBL:ENSP00000311083;ENSP00000409569|REFSEQ:NP_001817|H-INV:HIT000264275|VEGA:OTTHUMP00000035541 Tax_Id=9606 Gene_Symbol=CKS1B Cyclin-dependent kinases regulatory subunit 1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=CKS1B Cyclin-dependent kinases regulatory subunit 1 ENSG00000173207 IPI00015104 IPI00514250 IPI00643512 [drosphohumanreversed.fasta]
  • P61024;P33551; RecName: Full=Cyclin-dependent kinases regulatory subunit 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Cyclin-dependent kinases regulatory subunit 1 OS=Homo sapiens GN=CKS1B [011711_HMR.fasta]
  • GeneSymbol=CKS1B Synonyms=CKS1|PNAS-16|PNAS-18|ckshs1 cyclin-dependent kinases regulatory subunit 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00015104.1|SWISS-PROT:P61024|TREMBL:Q5T178|ENSEMBL:ENSP00000311083|REFSEQ:NP_001817|H-INV:HIT000264275|VEGA:OTTHUMP00000035541 Tax_Id=9606 Gene_Symbol=CKS1B Cyclin-dependent kinases regulatory subunit 1 [ipi.HUMAN.20110912.fasta]
  • Cyclin-dependent kinases regulatory subunit 1 GN=CKS1B [Doctor+uniprot-HUMAN-120911.fasta]
  • Cyclin-dependent kinases regulatory subunit OS=Homo sapiens GN=CKS1B PE=2 SV=1 [uniprot-human-031015-contam.fasta]
    • Organism: Homo sapiens
    Length: 79 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ SQGWVHYMIH  60
   61 EPEPHILLFR RPLPKKPKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] PSI-BLAST 34.39794 CksHs1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  1.72385894854644 bayes_pls_golite062009
  • binding
    		•  1.27976774437131 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  0.778971115132656 bayes_pls_golite062009
  • kinase regulator activity
    		•  0.498328649950238 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  0.47491756269249 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle