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Protein Overview: AMPD2

General Information:
Name(s) found: AMPD2 [HGNC (HUGO)]
Description(s) found:
Found 29 descriptions.
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  • adenosine monophosphate deaminase 2 (isoform L) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 879 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNRGQGLFR LRSRCFLHQS LPLGAGRRKG LDVAEPGPSR CRSDSPAVAA VVPAMASYPS  60
   61 GSGKPKAKYP FKKRASLQAS TAAPEARGGL GAPPLQSARS LPGPAPCLKH FPLDLRTSMD 120
  121 GKCKEIAEEL FTRSLAESEL RSAPYEFPEE SPIEQLEERR QRLERQISQD VKLEPDILLR 180
  181 AKQDFLKTDS DSDLQLYKEQ GEGQGDRSLR ERDVLEREFQ RVTISGEEKC GVPFTDLLDA 240
  241 AKSVVRALFI REKYMALSLQ SFCPTTRRYL QQLAEKPLET RTYEQGPDTP VSADAPVHPP 300
  301 ALEQHPYEHC EPSTMPGDLG LGLRMVRGVV HVYTRREPDE HCSEVELPYP DLQEFVADVN 360
  361 VLMALIINGP IKSFCYRRLQ YLSSKFQMHV LLNEMKELAA QKKVPHRDFY NIRKVDTHIH 420
  421 ASSCMNQKHL LRFIKRAMKR HLEEIVHVEQ GREQTLREVF ESMNLTAYDL SVDTLDVHAD 480
  481 RNTFHRFDKF NAKYNPIGES VLREIFIKTD NRVSGKYFAH IIKEVMSDLE ESKYQNAELR 540
  541 LSIYGRSRDE WDKLARWAVM HRVHSPNVRW LVQVPRLFDV YRTKGQLANF QEMLENIFLP 600
  601 LFEATVHPAS HPELHLFLEH VDGFDSVDDE SKPENHVFNL ESPLPEAWVE EDNPPYAYYL 660
  661 YYTFANMAML NHLRRQRGFH TFVLRPHCGE AGPIHHLVSA FMLAENISHG LLLRKAPVLQ 720
  721 YLYYLAQIGI AMSPLSNNSL FLSYHRNPLP EYLSRGLMVS LSTDDPLQFH FTKEPLMEEY 780
  781 SIATQVWKLS SCDMCELARN SVLMSGFSHK VKSHWLGPNY TKEGPEGNDI RRTNVPDIRV 840
  841 GYRYETLCQE LALITQAVQS EMLETIPEEA GITMSPGPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] deduced N/A No confident structure predictions are available.
    2 View Details [117..879] PSI-BLAST 1000.0 X-Ray Structure of Adenosine 5'-Monophosphate Deaminase from Arabidopsis Thaliana in Complex with Coformycin 5'-Phosphate

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrolase activity
    		•  2.00269452684807 bayes_pls_golite062009
  • catalytic activity
    		•  1.70199291046899 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.12925526582667 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
    		•  0.248802326836448 bayes_pls_golite062009
  • dihydroorotase activity
    		•  0.203044795244555 bayes_pls_golite062009
  • deaminase activity
    		•  0.18698811376434 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  0.0954028693917728 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle