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Protein Overview: CDC45

General Information:
Name(s) found: CDC45 [HGNC (HUGO)]
Description(s) found:
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  • gi|90403034|emb|CAJ86443.1| CDC45L [Homo sapiens] [NCBI NR]
  • gi|6685264|sp|O75419.1|CC45L_HUMAN RecName: Full=CDC45-related protein; Short=Cdc45; AltName: Full=PORC-PI-1 [NCBI NR]
  • gi|45505188|gb|AAS66985.1| CDC45 cell division cycle 45-like (S. cerevisiae) [Homo sapiens] [NCBI NR]
  • gi|4502713|ref|NP_003495.1| CDC45-like [Homo sapiens] [NCBI NR]
  • gi|4185277|gb|AAD08998.1| CDC45L [Homo sapiens] [NCBI NR]
  • gi|3283045|gb|AAC27289.1| CDC45L [Homo sapiens] [NCBI NR]
  • gi|30582423|gb|AAP35438.1| CDC45 cell division cycle 45-like (S. cerevisiae) [Homo sapiens] [NCBI NR]
  • gi|14603106|gb|AAH10022.1| CDC45 cell division cycle 45-like (S. cerevisiae) [Homo sapiens] [NCBI NR]
  • gi|13623265|gb|AAH06232.1| CDC45 cell division cycle 45-like (S. cerevisiae) [Homo sapiens] [NCBI NR]
  • gi|119623441|gb|EAX03036.1| CDC45 cell division cycle 45-like (S. cerevisiae) [Homo sapiens] [NCBI NR]
  • CDC45 cell division cycle 45-like (S. cerevisiae) [HGNC (HUGO)]
  • cell division cycle 45 homolog (S. cerevisiae) [HGNC (HUGO)]
  • Cell division control protein 45 homolog OS=Homo sapiens GN=CDC45 PE=1 SV=1 [Swiss-Prot]
  • (O75419) CDC45-related protein (PORC-PI-1) [Swiss-Prot]
  • CDC45-related protein OS=Homo sapiens GN=CDC45L PE=1 SV=1 [Swiss-Prot]
  • CDC45-related protein [hmr_yeast5_DM3-1_pombe.fasta]
  • CDC45-like; CDC45 (cell division cycle 45, S.cerevisiae, homolog)-like; cell division cycle 45-like 2; CDC45-related protein [HMR_022704.fasta]
  • CDC45-like [Homo sapiens]gi|30582423|gb|AAP35438.1| CDC45 cell division cycle 45-like (S. cerevisiae) [Homo sapiens]gi|14603106|gb|AAH10022.1| CDC45-like [Homo sapiens]gi|13623265|gb|AAH06232.1| CDC45-like [Homo sapiens]gi|4185277|gb|AAD08998.1| CDC45 [nrdb_11152004_Chlamydomonas]
  • CDC45-related protein (PORC-PI-1) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 CDC45-related protein [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_003504) CDC45-like; CDC45 (cell division cycle 45, S.cerevisiae, homolog)-like; cell division cycle 45-like 2; CDC45-related protein [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • CDC45-like [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • CDC45-like; CDC45 (cell division cycle 45, S.cerevisiae, homolog)-like; cell division cycle 45-like 2; CDC45-related protein [Homo sapiens] [HumanGallus06162005.fasta]
  • CDC45L [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • CDC45-related protein (Cdc45) (PORC-PI-1) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • CDC45 cell division cycle 45-like (S. cerevisiae) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 CDC45-RELATED PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=CDC45-related protein; Short=Cdc45; AltName: Full=PORC-PI-1 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=CDC45L CDC45-related protein [human-ipi-250309-contam.fasta]
  • CDC45-related protein (PORC-PI-1) (Cdc45) [nr-271106-contam.fasta]
  • IPI:IPI00025695.1|SWISS-PROT:O75419|TREMBL:Q20WK8|ENSEMBL:ENSP00000263201;ENSP00000385240;ENSP00000396647|REFSEQ:NP_003495|H-INV:HIT000282919|VEGA:OTTHUMP00000028524;OTTHUMP00000197247 Tax_Id=9606 Gene_Symbol=CDC45L CDC45-related protein [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=CDC45L CDC45-related protein ENSG00000093009 IPI00025695 [drosphohumanreversed.fasta]
  • CDC45-related protein [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • O75419;O60856;Q20WK8;Q6UW54;Q9UP68; RecName: Full=CDC45-related protein; AltName: Full=PORC-PI-1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Cell division control protein 45 homolog OS=Homo sapiens GN=CDC45 [011711_HMR.fasta]
  • IPI:IPI00025695.1|SWISS-PROT:O75419|ENSEMBL:ENSP00000263201;ENSP00000385240;ENSP00000396647|REFSEQ:NP_003495|H-INV:HIT000282919|VEGA:OTTHUMP00000028524;OTTHUMP00000197247 Tax_Id=9606 Gene_Symbol=CDC45L CDC45-related protein [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=CDC45 Synonyms=CDC45L|CDC45L2|PORC-PI-1 cell division control protein 45 homolog isoform 2 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00025695.1|SWISS-PROT:O75419|ENSEMBL:ENSP00000263201;ENSP00000385240|REFSEQ:NP_003495|H-INV:HIT000282919|VEGA:OTTHUMP00000197247 Tax_Id=9606 Gene_Symbol=CDC45 Cell division control protein 45 homolog [ipi.HUMAN.20110912.fasta]
  • Cell division control protein 45 homolog GN=CDC45 [Doctor+uniprot-HUMAN-120911.fasta]
  • Tax_Id=9606 Gene_Symbol=CDC45 Cell division control protein 45 homolog [human-ipi-270911-contam-BSA.fasta]
    • Organism: Homo sapiens
    Length: 566 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVSDFRKEF YEVVQSQRVL LFVASDVDAL CACKILQALF QCDHVQYTLV PVSGWQELET  60
   61 AFLEHKEQFH YFILINCGAN VDLLDILQPD EDTIFFVCDT HRPVNVVNVY NDTQIKLLIK 120
  121 QDDDLEVPAY EDIFRDEEED EEHSGNDSDG SEPSEKRTRL EEEIVEQTMR RRQRREWEAR 180
  181 RRDILFDYEQ YEYHGTSSAM VMFELAWMLS KDLNDMLWWA IVGLTDQWVQ DKITQMKYVT 240
  241 DVGVLQRHVS RHNHRNEDEE NTLSVDCTRI SFEYDLRLVL YQHWSLHDSL CNTSYTAARF 300
  301 KLWSVHGQKR LQEFLADMGL PLKQVKQKFQ AMDISLKENL REMIEESANK FGMKDMRVQT 360
  361 FSIHFGFKHK FLASDVVFAT MSLMESPEKD GSGTDHFIQA LDSLSRSNLD KLYHGLELAK 420
  421 KQLRATQQTI ASCLCTNLVI SQGPFLYCSL MEGTPDVMLF SRPASLSLLS KHLLKSFVCS 480
  481 TKNRRCKLLP LVMAAPLSME HGTVTVVGIP PETDSSDRKN FFGRAFEKAA ESTSSRMLHN 540
  541 HFDLSVIELK AEDRSKFLDA LISLLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] MSA 1.034973 View MSA. No confident structure predictions are available.
    2 View Details [167..252] MSA 1.037991 View MSA. Confident ab initio structure predictions are available.
    3 View Details [253..390] MSA 1.038974 View MSA. Confident ab initio structure predictions are available.
    4 View Details [391..566] MSA 1.036946 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle