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Protein Overview: B4GALT1

General Information:
Name(s) found: B4GALT1 [HGNC (HUGO)]
Description(s) found:
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  • gi|32058|emb|CAA39073.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|189053491|dbj|BAG35657.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|17384434|emb|CAD13306.1| UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1 [Homo sapiens] [NCBI NR]
  • gi|13929462|ref|NP_001488.2| UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form [Homo sapiens] [NCBI NR]
  • gi|119578925|gb|EAW58521.1| UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119578924|gb|EAW58520.1| UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|116241264|sp|P15291.5|B4GT1_HUMAN RecName: Full=Beta-1,4-galactosyltransferase 1; Short=Beta-1,4-GalTase 1; Short=Beta4Gal-T1; Short=b4Gal-T1; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1; AltName: Full=UDP-Gal: [NCBI NR]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 [HGNC (HUGO)]
  • Beta-1,4-galactosyltransferase 1 OS=Homo sapiens GN=B4GALT1 PE=1 SV=5 [Swiss-Prot]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form [hmr_yeast5_DM3-1_pombe.fasta]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form; glycoprotein-4-beta-galactosyltransferase 2; lactose synthase A protein [HMR_022704.fasta]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form; lactose synthase A protein; glycoprotein-4-beta-galactosyltransferase 2 [Human2242005.fasta]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form [Homo sapiens]gi|17384434|emb|CAD13306.1| UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1 [Homo sapiens]gi|32058|emb|CAA39073.1| unnamed protein product [Homo sap [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_001497) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form; beta-N-acetylglucosaminyl-glycopeptide beta-1,4-galactosyltransferase 1; glycoprotein 4-beta-galactosyltransferase 2; UDP-galactose-glycoprotein galactosyltransferase; [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form; lactose synthase A protein; glycoprotein-4-beta-galactosyltransferase 2 [Homo sapiens] [HumanGallus06162005.fasta]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 1, membrane-bound form; glycoprotein-4-beta-galactosyltransferase 2; lactose synthase A protein [Homo sapiens] [human-NCBI-042104-rand.fasta]
  • Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) [Includes: Lactose synthase A protein ; N-acety [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • galactosyltransferase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Isoform Long of Beta-1,4-galactosyltransferase 1 [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 UDP-GAL:BETAGLCNAC BETA 1,4- GALACTOSYLTRANSFERASE 1, MEMBRANE-BOUND FORM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=B4GALT1 Isoform Long of Beta-1,4-galactosyltransferase 1 [human-ipi-250309-contam.fasta]
  • beta-1,4-galactosyltransferase 1 [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta]
  • IPI:IPI00215767.1|SWISS-PROT:P15291-1|TREMBL:B2R710;B4DLB8;B4DMM8;B7ZAH9;Q86XA6|ENSEMBL:ENSP00000369055|REFSEQ:NP_001488|H-INV:HIT000321972|VEGA:OTTHUMP00000021196 Tax_Id=9606 Gene_Symbol=B4GALT1 Isoform Long of Beta-1,4-galactosyltransferase 1 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=B4GALT1 Isoform Long of Beta-1,4-galactosyltransferase 1 ENSG00000086062 IPI00215767 IPI00759755 [drosphohumanreversed.fasta]
  • P15291;B2R710;Q12909;Q12910;Q12911;Q14456;Q14509;Q14523; RecName: Full=Beta-1,4-galactosyltransferase 1; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; Includes: RecName: Full=Lactose synthase A protein; Includes: RecName: Full=N-acetyllactosamine synthase; AltName: Full=Nal synthase; Includes: RecName: Full=Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; Includes: RecName: Full=Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Contains: RecName: Full=Processed beta-1,4-galactosyltransferase 1; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform Long of Beta-1,4-galactosyltransferase 1 OS=Homo sapiens GN=B4GALT1 [011711_HMR.fasta]
  • IPI:IPI00215767.1|SWISS-PROT:P15291-1|TREMBL:B4DLB8;B4DMM8;B7ZAH9;D3DRL2;Q86XA6|ENSEMBL:ENSP00000369055|REFSEQ:NP_001488|H-INV:HIT000321972|VEGA:OTTHUMP00000021196 Tax_Id=9606 Gene_Symbol=B4GALT1 Isoform Long of Beta-1,4-galactosyltransferase 1 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=B4GALT1 Synonyms=B4GAL-T1|CDG2D|DKFZp686N19253|GGTB2|GT1|GTB|MGC50983|beta4Gal-T1 beta-1,4-galactosyltransferase 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00215767.1|SWISS-PROT:P15291-1|ENSEMBL:ENSP00000369055|REFSEQ:NP_001488|H-INV:HIT000321972|VEGA:OTTHUMP00000021196 Tax_Id=9606 Gene_Symbol=B4GALT1 Isoform Long of Beta-1,4-galactosyltransferase 1 [ipi.HUMAN.20110912.fasta]
  • Beta-1,4-galactosyltransferase 1 GN=B4GALT1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 398 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLREPLLSG SAAMPGASLQ RACRLLVAVC ALHLGVTLVY YLAGRDLSRL PQLVGVSTPL  60
   61 QGGSNSAAAI GQSSGELRTG GARPPPPLGA SSQPRPGGDS SPVVDSGPGP ASNLTSVPVP 120
  121 HTTALSLPAC PEESPLLVGP MLIEFNMPVD LELVAKQNPN VKMGGRYAPR DCVSPHKVAI 180
  181 IIPFRNRQEH LKYWLYYLHP VLQRQQLDYG IYVINQAGDT IFNRAKLLNV GFQEALKDYD 240
  241 YTCFVFSDVD LIPMNDHNAY RCFSQPRHIS VAMDKFGFSL PYVQYFGGVS ALSKQQFLTI 300
  301 NGFPNNYWGW GGEDDDIFNR LVFRGMSISR PNAVVGRCRM IRHSRDKKNE PNPQRFDRIA 360
  361 HTKETMLSDG LNSLTYQVLD VQRYPLYTQI TVDIGTPS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..76] MSA 2.054977 View MSA. No confident structure predictions are available.
    2 View Details [77..398] PSI-BLAST 143.0 beta 1,4 galactosyltransferase (b4GalT1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  8.87768693404638 bayes_pls_golite062009
  • lactose synthase activity
    		•  6.70934342374853 bayes_pls_golite062009
  • N-acetyllactosamine synthase activity
    		•  6.70934342374853 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  6.50620584399191 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  6.18010634203776 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  5.57855076532185 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  4.57071306027628 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  4.49413422196176 bayes_pls_golite062009
  • alpha-1,2-mannosyltransferase activity
    		•  3.80392076707564 bayes_pls_golite062009
  • glucuronosyltransferase activity
    		•  3.57513377728523 bayes_pls_golite062009
  • transferase activity
    		•  2.62166586999833 bayes_pls_golite062009
  • UDP-galactosyltransferase activity
    		•  2.58196286090865 bayes_pls_golite062009
  • galactosyltransferase activity
    		•  2.49617255507474 bayes_pls_golite062009
  • heparan sulfate N-acetylglucosaminyltransferase activity
    		•  2.42139682088952 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.01768771829228 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  1.6603302881547 bayes_pls_golite062009
  • beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
    		•  1.33105118629174 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.31793036737589 bayes_pls_golite062009
  • N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
    		•  1.11758321292207 bayes_pls_golite062009
  • protein binding
    		•  0.967722609820275 bayes_pls_golite062009
  • alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
    		•  0.734643988700831 bayes_pls_golite062009
  • binding
    		•  0.667238976803188 bayes_pls_golite062009
  • UDP-N-acetylglucosamine diphosphorylase activity
    		•  0.513376694534047 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  0.321928989676507 bayes_pls_golite062009
  • mannose-phosphate guanylyltransferase activity
    		•  0.2363835251362 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.218759888732981 bayes_pls_golite062009
  • glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
    		•  0.119213830545019 bayes_pls_golite062009
  • guanylyltransferase activity
    		•  0.0539392112504681 bayes_pls_golite062009
  • mannose-1-phosphate guanylyltransferase activity
    		•  0.040911758618571 bayes_pls_golite062009
  • acetylglucosaminyltransferase activity
    		•  0.0278258721775009 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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