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Protein Overview: SPO1

General Information:
Name(s) found: SPO1 / YNL012W [SGD]
Description(s) found:
Found 11 descriptions.
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  • Meiosis-specific prospore protein; required for meiotic spindle pole body duplication and separation; required to produce bending force necessary for proper prospore membrane assembly during sporulation; has similarity to phospholipase B [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: meiosis [IMPLink to PubMed article]
    Molecular Function: phospholipase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVGTGFISQ MNDYGLFEYS DYIAGLSGGS WILMDLVVQN FEVKSLLQEW DLEEDLLLGI  60
   61 PEFDISEEEI VTNAKKEYND NDLKMKKRQG GSLITSSSNF YEQIEEIMNS IEEIPEDYMI 120
  121 TKRNLNPLAR LKKIFFPNNT FTGTDAKIET FKKVLDFYKS LHLKIKPKKM EGFQISFTDY 180
  181 WGKAIVQRLK KNFDDDPNHS FSFSKLVNSS KKFKECSVPI PIFVANCKNG LLSNVIFEFT 240
  241 PFEFGSWENI LRLFVKLPYL GSKIVSGKAE KCINNFDDLG FITATSSSIF NNVLIFIWNL 300
  301 ASQSSREAMK ALNMVMGIFG LGKEEIFSIS KDSSRLETDY AVYQPNPFYL YPEKDNVLTN 360
  361 KNHLYLVDGG EDGENIPLRT LVIPERELDV IFVLDSSSDI DNYPNGSKLK RIFEKLDEEN 420
  421 VHYQFPNNVK TFTHPIVIGC NATKRTGHDS FLPIIIYHAN ANHGNASNTS TFKITYNQSE 480
  481 VSSMLPTGRG VFSNDYDLYY KNCLGCILTK RTMDRLPRKK KFSPFCLQCF KDYCYS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142] deduced N/A No confident structure predictions are available.
    2 View Details [143..301] PSI-BLAST 3.30103 Domain from cytosolic phospholipase A2; Cytosolic phospholipase A2 catalytic domain
    3 View Details [302..536] ORFEUS 10.23 Domain from cytosolic phospholipase A2; Cytosolic phospholipase A2 catalytic domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle