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Protein Overview: FGF7

General Information:
Name(s) found: FGF7 [HGNC (HUGO)]
Description(s) found:
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  • gi|49456957|emb|CAG46799.1| FGF7 [Homo sapiens] [NCBI NR]
  • gi|4503705|ref|NP_002000.1| fibroblast growth factor 7 precursor [Homo sapiens] [NCBI NR]
  • gi|245439|gb|AAB21431.1| Keratinocyte growth factor; KGF [Homo sapiens] [NCBI NR]
  • gi|189053726|dbj|BAG35978.1| unnamed protein product [Homo sapiens] [NCBI NR]
  • gi|186739|gb|AAA63210.1| keratinocyte growth factor [Homo sapiens] [NCBI NR]
  • gi|122756|sp|P21781.1|FGF7_HUMAN RecName: Full=Keratinocyte growth factor; Short=KGF; AltName: Full=Fibroblast growth factor 7; Short=FGF-7; AltName: Full=Heparin-binding growth factor 7; Short=HBGF-7; Flags: Precursor [NCBI NR]
  • gi|119597782|gb|EAW77376.1| hCG2001865, isoform CRA_b [Homo sapiens] [NCBI NR]
  • pir||A36301 fibroblast growth factor 7 precursor [validated] - human [NCBI NR]
  • fibroblast growth factor 7 (keratinocyte growth factor) [HGNC (HUGO)]
  • Fibroblast growth factor 7 OS=Homo sapiens GN=FGF7 PE=1 SV=1 [Swiss-Prot]
  • [hmr_yeast5_DM3-1_pombe.fasta]
  • Keratinocyte growth factor precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • fibroblast growth factor 7 precursor; keratinocyte growth factor [HMR_022704.fasta]
  • fibroblast growth factor 7 precursor [Homo sapiens]gi|122756|sp|P21781|FGF7_HUMAN Keratinocyte growth factor precursor (KGF) (Fibroblast growth factor-7) (FGF-7) (HBGF-7)gi|106857|pir||A36301 fibroblast growth factor 7 precursor [validated] - humangi|2 [nrdb_11152004_Chlamydomonas]
  • [pompep4896_normal_reversed]
  • Keratinocyte growth factor precursor (KGF) (Fibroblast growth factor-7) (FGF-7) (HBGF-7) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Keratinocyte growth factor precursor [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_002009) fibroblast growth factor 7 precursor; keratinocyte growth factor [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • [contaminent] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • fibroblast growth factor 7 precursor [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • fibroblast growth factor 7 precursor; keratinocyte growth factor [Homo sapiens] [HumanGallus06162005.fasta]
  • Keratinocyte growth factor precursor (KGF) (Fibroblast growth factor 7) (FGF-7) (HBGF-7) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Keratinocyte growth factor; KGF [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • hCG2001865, isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • FGF7 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • keratinocyte growth factor [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 KERATINOCYTE GROWTH FACTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=FGF7 Keratinocyte growth factor [human-ipi-250309-contam.fasta]
  • IPI:IPI00010403.1|SWISS-PROT:P21781|TREMBL:Q6FGV5|ENSEMBL:ENSP00000267843|REFSEQ:NP_002000|H-INV:HIT000195965|VEGA:OTTHUMP00000162252;OTTHUMP00000175798 Tax_Id=9606 Gene_Symbol=FGF7P2;FGF7 Keratinocyte growth factor [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Gene_Symbol=FGF7 Keratinocyte growth factor precursor ENSG00000140285 IPI00010403 IPI00789446 IPI00852718 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=FGF7 Keratinocyte growth factor precursor [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=FGF7P2;FGF7 Keratinocyte growth factor [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta]
  • IPI:IPI00010403.1|SWISS-PROT:P21781|TREMBL:Q6FGV5;Q96FG5;Q6RK68|REFSEQ_NP:NP_002000|ENSEMBL:ENSP00000267843|H-INV:HIT000035144 Tax_Id=9606 Keratinocyte growth factor precursor [ipi.MOUSE.fasta.20090209]
  • keratinocyte growth factor precursor [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Keratinocyte growth factor OS=Homo sapiens GN=FGF7 PE=1 SV=1 [UniProtHuman070710.fasta]
  • P21781; RecName: Full=Keratinocyte growth factor; AltName: Full=Fibroblast growth factor 7; AltName: Full=Heparin-binding growth factor 7; Flags: Precursor; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Keratinocyte growth factor OS=Homo sapiens GN=FGF7 [011711_HMR.fasta]
  • GeneSymbol=FGF7 Synonyms=HBGF-7|KGF keratinocyte growth factor precursor [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00010403.1|SWISS-PROT:P21781|TREMBL:Q6FGV5;Q96FG5|ENSEMBL:ENSP00000267843|REFSEQ:NP_002000|H-INV:HIT000195965|VEGA:OTTHUMP00000162252 Tax_Id=9606 Gene_Symbol=FGF7P2;FGF7 Keratinocyte growth factor [ipi.HUMAN.20110912.fasta]
  • Fibroblast growth factor 7 GN=FGF7 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 194 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKWILTWIL PTLLYRSCFH IICLVGTISL ACNDMTPEQM ATNVNCSSPE RHTRSYDYME  60
   61 GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA 120
  121 MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK 180
  181 KEQKTAHFLP MAIT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..194] PSI-BLAST 47.154902 Keratinocyte growth factor, FGF7

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • fibroblast growth factor receptor binding
    		•  5.68976822724664 bayes_pls_golite062009
  • growth factor activity
    		•  5.6790632853895 bayes_pls_golite062009
  • receptor binding
    		•  4.8109037277027 bayes_pls_golite062009
  • cytokine activity
    		•  3.72907359340826 bayes_pls_golite062009
  • protein binding
    		•  2.99442649109752 bayes_pls_golite062009
  • binding
    		•  2.90110516688922 bayes_pls_golite062009
  • type 2 fibroblast growth factor receptor binding
    		•  1.96512066847854 bayes_pls_golite062009
  • heparin binding
    		•  1.71092312487163 bayes_pls_golite062009
  • signal transducer activity
    		•  1.24692031673405 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.24692031673405 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.04794819242244 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.55309369051712 bayes_pls_golite062009
  • pattern binding
    		•  0.323275442862789 bayes_pls_golite062009
  • nerve growth factor receptor binding
    		•  0.308245352535379 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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