Protein Overview: MCT1

General Information:
Name(s) found:	MCT1 / YOR221C [SGD]
Description(s) found: SHOW ONLY BEST	ref\|NP_014864.1\| Mct1p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S60948 MCT1 protein - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1420512\|emb\|CAA99439.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|1050773\|emb\|CAA63184.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] MCT1 malonyl-CoA:ACP transferase EC:2.3.1.39 [mips] Predicted malonyl-CoA:ACP transferase, putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling [SGD] >Q12283 (Q12283) Chromosome XV reading frame ORF YOR221C [4932.FASTACCERV.txt] Chr XV from 757831-757738,757536-756476, reverse complement [hmr_yeast5_DM3-1_pombe.fasta] Chr XV from 756475-756568,756770-757830, reverse complement [yeastorf3.fasta] Chr XV from 756476-756569,756771-757831, reverse complement [yeastorf4.fasta] MCT1, Chr XV from 756475-756568,756770-757830, reverse complement [yeast_orfs2] MCT1 SGDID:S0005747, Chr XV from 757831-757738,757536-756476, reverse complement, Verified ORF [yeastflysequest.fasta] Mct1p [Saccharomyces cerevisiae]gi\|1420512\|emb\|CAA99439.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|1050773\|emb\|CAA63184.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|2132088\|pir\|\|S60948 MCT1 protein - yeast (Saccharomyces cerevis [nrdb_11152004_Chlamydomonas] (Q12283) S.cerevisiae chromosome XV reading frame ORF YOR221c (YOR50-11) [cerv4932.FASTAC] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	384 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA][IMP][ISS]
Biological Process:	aerobic respiration [IMP] fatty acid metabolic process [IMP][ISS]
Molecular Function:	[acyl-carrier-protein] S-malonyltransferase activity [IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVLRKLEEN YRPLNILKMQ KVSSSYMAFF GRQGTSISIS ILKAIIRNKS REFQTILSQN  60
   61 GKESNDLLQY IFQNPSSPGS IAVCSNLFYQ LYQILSNPSD PQDQAPKNMT KIDSPDKKDN 120
  121 EQCYLLGHSL GELTCLSVNS LFSLKDLFDI ANFRNKLMVT STEKYLVAHN INRSNKFEMW 180
  181 ALSSPRATDL PQEVQKLLNS PNLLSSSQNT ISVANANSVK QCVVTGLVDD LESLRTELNL 240
  241 RFPRLRITEL TNPYNIPFHN STVLRPVQEP LYDYIWDILK KNGTHTLMEL NHPIIANLDG 300
  301 NISYYIHHAL DRFVKCSSRT VQFTMCYDTI NSGTPVEIDK SICFGPGNVI YNLIRRNCPQ 360
  361 VDTIEYTSLA TIDAYHKAAE ENKD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NUP2	MCT1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..384]	PSI-BLAST	57.09691	Catalytic domain of malonyl-CoA ACP transacylase FabD; Probable ACP-binding domain of malonyl-CoA ACP transacylase

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.82

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2