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Protein Overview: ALE1

General Information:
Name(s) found: ALE1 / YOR175C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Broad-specificity lysophospholipid acyltransferase, part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 619 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed article]
    ribosome [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: O-acyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNPVDAVLT KIITNYGIDS FTLRYAICLL GSFPLNAILK RIPEKRIGLK CCFIISMSMF  60
   61 YLFGVLNLVS GFRTLFISTM FTYLISRFYR SKFMPHLNFM FVMGHLAINH IHAQFLNEQT 120
  121 QTTVDITSSQ MVLAMKLTSF AWSYYDGSCT SESDFKDLTE HQKSRAVRGH PPLLKFLAYA 180
  181 FFYSTLLTGP SFDYADFDSW LNCEMFRDLP ESKKPMRRHH PGERRQIPKN GKLALWKVVQ 240
  241 GLAWMILSTL GMKHFPVKYV LDKDGFPTRS FIFRIHYLFL LGFIHRFKYY AAWTISEGSC 300
  301 ILCGLGYNGY DSKTQKIRWD RVRNIDIWTV ETAQNTREML EAWNMNTNKW LKYSVYLRVT 360
  361 KKGKKPGFRS TLFTFLTSAF WHGTRPGYYL TFATGALYQT CGKIYRRNFR PIFLREDGVT 420
  421 PLPSKKIYDL VGIYAIKLAF GYMVQPFIIL DLKPSLMVWG SVYFYVHIIV AFSFFLFRGP 480
  481 YAKQVTEFFK SKQPKEIFIR KQKKLEKDIS ASSPNLGGIL KAKIEHEKGK TAEEEEMNLG 540
  541 IPPIELEKWD NAKEDWEDFC KDYKEWRNKN GLEIEEENLS KAFERFKQEF SNAASGSGER 600
  601 VRKMSFSGYS PKPISKKEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YOL014W ALE1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ALE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..143] MSA 1.065994 View MSA. Confident ab initio structure predictions are available.
    2 View Details [144..512] Pfam 180.60206 MBOAT family No confident structure predictions are available.
    3 View Details [513..619] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle