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Protein Overview: CYT2

General Information:
Name(s) found: CYT2 / YKL087C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1 [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 224 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: cytochrome c-heme linkage [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: holocytochrome-c synthase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSSDQQGKC PVDEETKKLW LREHGNEAHP GATAPGNQLE CSANPQDNDK TPEYHTTVDL  60
   61 SQSREVSTIP RTNSDRNWIY PSEKQFYEAM MKKNWDPNSD DMKVVVPLHN SINERVWNYI 120
  121 KSWEDKQGGE ACGGIKLTNF KGDSKKLTPR AWFRSRILHL AKPFDRHDWQ IDRCGKTVDY 180
  181 VIDFYSTDLN DANSQQQPLI YLDVRPKLNS FEGFRLRFWK SLGF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) CYC3 CYT2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen RRB1 CYT2 1 Unpublished Fields Lab Data
    View Screen SMC5 CYT2 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..224] Pfam 148.236572 Cytochrome c/c1 heme lyase No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle