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Protein Overview: JAC1

General Information:
Name(s) found: JAC1 / YGL018C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria, involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 184 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: aerobic respiration [IMPLink to PubMed article]
    iron-sulfur cluster assembly [IMPLink to PubMed article]
    Molecular Function: chaperone binding [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKYLVQRRF TSTFYELFPK TFPKKLPIWT IDQSRLRKEY RQLQAQHHPD MAQQGSEQSS  60
   61 TLNQAYHTLK DPLRRSQYML KLLRNIDLTQ EQTSNEVTTS DPQLLLKVLD IHDELSQMDD 120
  121 EAGVKLLEKQ NKERIQDIEA QLGQCYNDKD YAAAVKLTVE LKYWYNLAKA FKDWAPGKQL 180
  181 EMNH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data JAC1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..71] PSI-BLAST 83.9897 HSC20 (HSCB), N-terminal (J) domain; HSC20 (HSCB), C-terminal oligomerisation domain
    2 View Details [72..184] PSI-BLAST 83.9897 HSC20 (HSCB), N-terminal (J) domain; HSC20 (HSCB), C-terminal oligomerisation domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.106988907594358 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle