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Protein Overview: l(2)44DEa-PD

General Information:
Name(s) found: l(2)44DEa-PD / FBpp0099845 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • The gene lethal (2) 44DEa is referred to in FlyBase by the symbol Dmel\l(2)44DEa (CG8732, FBgn0010609). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4553360..4570296. It has the cytological map location 44E1-44E2. Based on sequence similarity, it is predicted to have molecular function</span>: long-chain-fatty-acid-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 34 alleles are reported. No phenotypic data is available. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 717 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    Biological Process: metabolic process [IEA]
    Molecular Function: long-chain fatty acid-CoA ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYNSLSYCV MDSFWVQSAI GAIKAIAFVY DIITLPVYLV LQKPWKRRQD SRRVKAKIVR  60
   61 NDDNELTYRT TDPPRDVHVK MLQENIDTLE KVFNYVAKTY TSKRCLGTRQ ILSEEDEVQQ 120
  121 NGRVFKKYNL GDYKWKTFTE AERTAANFGR GLRELGQKPR ENIVIFAETR AEWMIAAHGC 180
  181 FKQAMPIVTV YATLGDDGVA HCITETEVTT VITSHDLLPK FKTLLDKCPL VKTIIYIEDQ 240
  241 LQKTETTGFK EGVKILPFNQ VVKTGQDSKF EHVPPKGDDI AIIMYTSGST GTPKGVLLSH 300
  301 KNCIATMKGF VDMVPIYPDD VLIGFLPLAH VFELVAESVC LMTGVPIGYS TPLTLIDTSS 360
  361 KIKRGCKGDA TVLKPTCMTS VPLILDRISK GINDKVNSGS AFKKSLFKFL YQYKVKWVQR 420
  421 GYKTPLIDKL VFKKVAKLMG GKVRIIMSGG APLSADTHEQ IKTCLCLELI QGYGLTETTS 480
  481 GATVMDYRDM TYGRTGGPLT VCDIRLVNWE EGNYRVTNKP YPQGEVLIGG ECVSQGYYKL 540
  541 PGKTNEDFFE EDGQRWFKTG DIGEIQADGV LKIIDRKKDL VKLQAGEYVS LGKVESELKT 600
  601 CGIIENICVY GDPTKQYTVA LVVPNQNHLE ELAQKHGLGD KSFEELCSSP IIEKAILKEI 660
  661 AEHARKCKLQ KYEVPAAITL CKEVWSPDMG LVTAAFKLKR KDIQDRYQHD INRMYAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..717] PSI-BLAST 137.0 No description for 2p2bA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.39

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle