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Protein Overview: CG11727-PA

General Information:
Name(s) found: CG11727-PA / FBpp0073392 [FlyBase]
Description(s) found:
Found 16 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG11727 (CG11727, FBgn0030299). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11326945..11348335. It has the cytological map location 10B11-10B14. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: Rab GTPase activator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of Rab GTPase activity. 5 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 807 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of Rab GTPase activity [IEA]
    Molecular Function: Rab GTPase activator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLTTTTTAS SAESQAKMDV KGGALPGEEN LPTSEMDLLA KLEAANKLIE SDAKSLNSLH  60
   61 STHSRKNSDT SQISLTSSGN SVAEEDIWTT WATILNDWEG ALKRKNPCVS ELVRRGIPHH 120
  121 FRAIVWQQLS GASDGDKKQY AEYIKATSAC EKVIRRDIAR TYPEVEFFKE KDGPGQEALF 180
  181 NVIKAYSLHD REVGYCQGSG FIVGLLLMQM PEEEAFAVLV QIMQQHRMRH MFKPSMSELG 240
  241 LCMYQLENLV QEQIPDMHIH FQQQGFQTTM YASSWFLTLY TTTLNVNLSC RIMDVFLSEG 300
  301 MEFIFKVALA LLLTGKDTLL CLDMEAMLKF FQKELPGRVE ADVEGFFNLA YSIKLNTKRM 360
  361 KKMEKEYQDL KKKEQEEMAE LRRLRRENCL LKQRNELLEA ESAELADRLV RGQVSRAEEE 420
  421 ETSYAIQTEL MQLRRSYLEV SHQLENANEE VRGLSLRLQE NNVSIDSNNS RQSSIDELCM 480
  481 KEEALKQRDE MVSCLLEELV KVRQGLAESE DQIRNLKAKV EELEEDKKTL RETTPDNSVA 540
  541 HLQDELIASK LREAEASLSL KDLKQRVQEL SSQWQRQLAE NQRSESERTT NAVDSTPKKL 600
  601 LTNFFDSSKS SEHTQKLEEE LMTTRIREME TLTELKELRL KVMELETQVQ VSTNQLRRQD 660
  661 EEHKKLKEEL EMAVTREKDM SNKAREQQHR YSDLESRMKD ELMNVKIKFT EQSQTVAELK 720
  721 QEISRLETKN SEMLAEGELR ANLDDSDKVR DLQDRLADMK AELTALKSRG KFPGAKLRSS 780
  781 SIQSIESTEI DFNDLNMVRR GSTELST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..66] deduced N/A No confident structure predictions are available.
    2 View Details [67..355] PSI-BLAST 50.30103 No description for 2qq8A was found.
    3 View Details [356..443] FFAS03 1.16 No description for 2fxmA was found.
    4 View Details [444..807] PSI-BLAST 20.69897 Heavy meromyosin subfragment


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle