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Protein Overview: IFKA_DICDI

General Information:
Name(s) found: IFKA_DICDI [Swiss-Prot]
Description(s) found:
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  • gi|74857726|sp|Q558U1.1|IFKA_DICDI RecName: Full=Probable serine/threonine-protein kinase ifkA; AltName: Full=Initiation factor kinase A [NCBI NR]
  • gi|60473108|gb|EAL71056.1| eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinase [Dictyostelium discoideum] [NCBI NR]
  • Probable serine/threonine-protein kinase ifkA OS=Dictyostelium discoideum GN=ifkA PE=2 SV=1 [Swiss-Prot]
    • Organism: Dictyostelium discoideum
    Length: 2258 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IC]
    Biological Process: cell-cell adhesion [IGI]
    regulation of translation [IMP]
    tRNA aminoacylation for protein translation [ISS]
    aggregation involved in sorocarp development [IMP]
    mRNA stabilization [IMP]
    cell-substrate adhesion [IGI]
    regulation of translational initiation [ISS]
    protein amino acid phosphorylation [IMP]
    negative regulation of aggregate size involved in sorocarp development [IMP]
    cAMP-mediated signaling [IMP]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IC]
    translation initiation factor activity [IEA]
    aminoacyl-tRNA ligase activity [ISS]
    eukaryotic translation initiation factor 2alpha kinase activity [IMP][ISS]
    transferase activity [IEA]
    kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPGEIIIFE LCQAVQEFLL LYNKETVSLH EEMIKRLNTN INRVNSSDDI NNNNNNNNDD  60
   61 DDDNDDYDDS DDENSDSDYD DYDDSDDENS DDEFYSDDED YNTRHQMGDI GSSVNKIINS 120
  121 IDHTISHGGG VGVGIGSGNG LFSKSSSSSS PMIPYNFSFD SLNGFDPDII FEDSFQTPLK 180
  181 GSSSIDFEEM NNLTNSNNSN STATTTTTTT TNNNNNNNTN NNNNNNSNNN NNNNNNNNNT 240
  241 NNNTNNNNNN NNNNNNNNNN NNNNNNNNNN NSNNNNNISN NKINKINNNN NNKELIDNNN 300
  301 NNKDKENDLI NDTIPKIKWK KGSCIERKSN YSVYRGVDED TDRKLICKIV NLNIDDRSSS 360
  361 SLTSLSNSNN NNSNNNNNNN NNNNNNNNNN NNNNNNNNLS IDVVELKKRL IEKVKMIQKE 420
  421 IESMKYLGNP YIIKYLGTNF QEGQNTLYIF QEYNSTLTLQ QKILSNGIGF EESQVKKFTY 480
  481 QLLLGLLYLH SQHIPHRDFK SHNIFFNQST SKMLLSNYGG RNIKIFDHFE KLNSLKNLNS 540
  541 WISSTNNSIN NINNINNNNN NNNNNINTTT TQNQINNEID RREDIINLGI VVLEMLCGSD 600
  601 LANNQTVLIY LAQLNLLNNQ QQNQNFIQPP PLQYQLQQQY DLIKEIEQKT HPSSPISNNA 660
  661 KDFLSLCFTI NGNGSTNDSL EAGILLKHPF LASNSNSTPP PSNFLNFTNN IKFLDQRSAA 720
  721 TQALLSSPHS LIPQPIQTLI KSQTPNNNND NNNLASSNEL LSSSNGSNID LRSTNSSIVS 780
  781 NPLATSSSLD NITPPPSRPI SPKPSPLNKR NQKLQTSQQK PPLSPPQTPL KQIPQSPQSP 840
  841 PQQNFNTPPT TTTTTTTPTA TPTTPTMTPL TPIQKQQQID YDMFRYHSRY RTDFEEIEMI 900
  901 GKGGFGVVVK SRNKLDCRYY AIKKIKTKGY TDSNQEPLTN KLLREVTTLS RLHHQFVVRY 960
  961 YQAWIEKSCD SFQSLEEGNE DLSGDLETDA SEDWFMQSSI NSRSIISRDS YSGLSTSNSN1020
 1021 VGGVNNTAGG GDSVSNANSN KSMIVGNSNK KLTLSSSNTS SSSSLLSNNK SKILNTSKST1080
 1081 STNTSTSTST SNTNKNKKIS KKKKSKLSPL MKPKNKKNKN NGESEQSSSD SENGENGMKS1140
 1141 RIIENASDSY SDDDNNNNNN NDNNNNYHSD NESDSFSGSI SMSDGNGSGY EATDDEDIIN1200
 1201 NSGSFDENEN DDDDEEDDDD EYDEEDDDYE TFDFQDKSRV VSNNSKLSTS SSRKKPPKET1260
 1261 HTLYIQMEYC SKKTLKTLID NVGGIAEEEA FRLLRQIVEG LNHIHSQQII HRDLKPANIF1320
 1321 IDNEQNVKIG DFGLATSGAP VSKSDDLNSS TSNTANNINL SSSTNSTAQQ TPMWDLNDEN1380
 1381 LSMTGGVGTP FYCCPEILEK NTKHYGTKVD MYSLGIIFFE MCFQFQTQME RSNILRDLRD1440
 1441 NLKFPPGFES TKPDQTQIIR SLLSRDPTQR PSTKQLLESG LLPSKMEDDI LKEAIKTIAN1500
 1501 PTISLFSYLM EKLFCLSNDE HIMSRYLYTS NPSLTPMHLI CREKTFSRLE KIFLNHGSIR1560
 1561 IDTPTLFPKN PTNSTHPGAA NVAKFLDESG TVVYLPYDLT IPWARHVVIH NIQQAKRYTF1620
 1621 SKVYRRSQPG FSPKELYECD FDIIGPSKSR HISDAETLRI IIEIMEEFKD ELFGNNSGSN1680
 1681 SGSGSGGSIN YKIRINHYGL LDSILSECGV EKRFFTVVYQ TVAQLHWRLN WAQVAQSLKE1740
 1741 HGLSASIVSN ISTYFRQRGE LAQCVTQLES LLANHKEATT GISDLKILVR NLQMINIIPR1800
 1801 FLLDLSLIHN HQYYEGLVFQ AYIERPTLSN PSRTEIIMSG GRYDKLIKSL HPNPSLSNNI1860
 1861 VSGVGVTLAC EKIVNSVLNY RQHLLNNCFN TTYTRRNKDP PNSNNNPNNN NLNNNVSIFT1920
 1921 KFQSHIEVFV CSLGSSLLGE KLQVASQLWS AGIKADYSQT DYYSSEDIYS NCRENGIPWV1980
 1981 VILREKAFQI GKLKVKQIET RQERTVARKD LVDFFLKSRK HNVDSKNIIQ NTSSSDLSNL2040
 2041 IGGINNSGSG GSGGSGGGSS MSSGGGGGGN SNIGGSDHHH HGHHSNQSTS SSGNSNNSNT2100
 2101 QQTSPIQHHV HFSNTKSIIG SSGIISNATF SGGSSSSSNI IHFDEPTDSF STQIVYQGVE2160
 2161 EIKKSKIETL VQTSLSKLFR GFIQSKSSTI RVIVTDLAYS VIRDLQISES HDNISKFQRV2220
 2221 SKEKLLQLKN QIFKWKVYPF IVIHSIKDDK SVIFNSVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle