Protein Overview: vari-PD

General Information:
Name(s) found:	vari-PD / FBpp0088884 [FlyBase]
Description(s) found: Found 17 descriptions. SHOW ALL	The gene varicose is referred to in FlyBase by the symbol Dmel\vari (CG9326, FBgn0250785). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:20788659..20797040. It has the cytological map location 39D3-40B1. Based on sequence similarity, it is predicted to have molecular function</span>: guanylate kinase activity. There is experimental evidence that it is involved in the biological process</span>: dorsal trunk growth, open tracheal system; regulation of tube size, open tracheal system; open tracheal system development; regulation of tube length, open tracheal system; septate junction assembly. 29 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; embryonic/larval tracheal system; portion of tissue; tracheal system; trachea; embryonic dorsal trunk; larval dorsal trunk; wing hair; embryonic tracheal system; embryonic ganglionic branch; external compound sense organ; plasma membrane part. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	615 amino acids
Gene Ontology:
Cellular Component:	lateral plasma membrane [IDA] membrane [ISS] septate junction [IDA]
Biological Process:	dorsal trunk growth, open tracheal system [IMP] regulation of tube size, open tracheal system [IMP] septate junction assembly [IMP] regulation of tube length, open tracheal system [IMP] open tracheal system development [IMP]
Molecular Function:	protein binding [IEA] guanylate kinase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRWSARSRR QARQDKVELL ARNNKVNGED DTSDNAAFRN STDLSDHDEI FLKGLLRSNS  60
   61 NTPHKELMLN PTEPQPVPLF LPAHLNNKPI CDDIIRKFSP SRRLESRELA KLLAQPHFRA 120
  121 LLRAHDEIGA LYEQRLKAAG GSTSQLEIAS QRQTGGYLFT EDVLNTKMPV ETIKMVGLRR 180
  181 DPSKPLGLTV ELDEFKQLVV ARILAGGVID KQSMLHVGDV ILEVNGTPVR TPDELQVEVS 240
  241 RAKENLTLKI GPNVDEEIKS GRYTCYMRAL FTYNPSEDSL LPCRDIGLPF KSGDILQIIN 300
  301 VKDPNWWQAK NITAESDKIG LIPSQELEER RKAFVAPEAD YVHKIGICGT RISKRKRKTM 360
  361 YRSVANCEFD KAELLLYEEV TRMPPFRRKT LVLIGVSGVG RRTLKNRLIN SDVDKFGAVI 420
  421 PHTSRPKRAL EENGSSYWFM DREEMEEAVR NNEFLEYGEH NGNLYGTHLQ SIKDVINSGR 480
  481 MCILDCAPNA LKILHNSQEL MPFVIFVAAP GMEQLKTIYA DRRATGSNRN LSFDRQSSIR 540
  541 FSSRRARTLE SLASLYEDDD LVATVEESSF VQRKYEKYFD MVIVNEDFDE TFRQVVETLD 600
  601 QMSHEEQWVP VNWIY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: vari-PD

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: