Protein Overview: RPOA_ECOL6

General Information:
Name(s) found:	RPOA_ECOL6 [Swiss-Prot]
Description(s) found: Found 4 descriptions. SHOW ALL	DNA-directed RNA polymerase subunit alpha OS=Escherichia coli O6 GN=rpoA PE=3 SV=1 [Swiss-Prot]
Organism:	Escherichia coli O6
Length:	329 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQGSVTEFLK PRLVDIEQVS STHAKVTLEP LERGFGHTLG NALRRILLSS MPGCAVTEVE  60
   61 IDGVLHEYST KEGVQEDILE ILLNLKGLAV RVQGKDEVIL TLNKSGIGPV TAADITHDGD 120
  121 VEIVKPQHVI CHLTDENASI SMRIKVQRGR GYVPASTRIH SEEDERPIGR LLVDACYSPV 180
  181 ERIAYNVEAA RVEQRTDLDK LVIEMETNGT IDPEEAIRRA ATILAEQLEA FVDLRDVRQP 240
  241 EVKEEKPEFD PILLRPVDDL ELTVRSANCL KAEAIHYIGD LVQRTEVELL KTPNLGKKSL 300
  301 TEIKDVLASR GLSLGMRLEN WPPASIADE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..237]	PSI-BLAST	75.69897	RNA polymerase alpha; RNA polymerase alpha subunit
2	View Details	[238..329]	PSI-BLAST	30.0	THE COOH-TERMINAL DOMAIN OF RNA POLYMERASE ALPHA SUBUNIT

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
DNA-directed RNA polymerase activity	9.7234602659063	bayes_pls_golite062009
RNA polymerase activity	9.7234602659063	bayes_pls_golite062009
nucleotidyltransferase activity	7.15121167353057	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	5.00321253017182	bayes_pls_golite062009
transferase activity	4.43019288788219	bayes_pls_golite062009
binding	1.71036005361152	bayes_pls_golite062009
catalytic activity	1.14991565197115	bayes_pls_golite062009
nucleic acid binding	0.912313560512218	bayes_pls_golite062009
DNA binding	0.830570793255009	bayes_pls_golite062009
protein binding	0.224464975113154	bayes_pls_golite062009

2

Term	Confidence	Notes
DNA-directed RNA polymerase activity	9.80450362116562	bayes_pls_golite062009
RNA polymerase activity	9.80450362116562	bayes_pls_golite062009
nucleotidyltransferase activity	7.23643031680113	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	5.11216561090158	bayes_pls_golite062009
transferase activity	4.56918356543307	bayes_pls_golite062009
catalytic activity	1.48339787978627	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle