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Protein Overview: CE39515

General Information:
Name(s) found: CE39515 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00019726 status:Partially_confirmed UniProt:Q94287 protein_id:CCD70205.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 640 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: regulation of ARF protein signal transduction [IEALink to PubMed article]
    Molecular Function: ARF guanyl-nucleotide exchange factor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRETKEWRGT TSTSRVFVQK GYQLSDELAL RKVQVLERRY GGMQLAHRAA TVIQRAWREY  60
   61 CIMKQWMVIR HKHDTIPDHL DARCGVSNSQ RNELSLTSRY ATSLSAQLRI DRAARSTTLD 120
  121 RSPPSPAPPV LVNLQNSNMI DSLMSPRLGN RRFGAAASRC APAAAELTST EVWLPRPSLV 180
  181 NHNPAHSNSL PRLDKHRVHE RSESSNGRKK SEVKPPRQMT DQERKRQYRI ALNFFNKKPE 240
  241 RGVQLLTAWG FVKNSPDSLA SLLFGRRGLS KSMIGEYIGT LHSPYHSLVL KYFTALIDIR 300
  301 GLEVDVALRK AMQFFILPKE AEKIDRIIQA FALHYSKSNP KRTSHYRGGW DTIHLLSFAI 360
  361 IMLNTDLHSP NVKQRMTQAD FVKNLRGQDK ISGEKNGEDI DRKTLEGIYD RIKKDELKAG 420
  421 DDHVAQVQRV DRAIVGKDKP RLTETPRRLV CYCRLQQVSD PTKRQSSSAR ERDVFLFNDM 480
  481 IVVAKGVRRG STSMAGCTYT LKQWTLLLGA HVTEFQRGQY EFGLTITCPN KDKIHFNARN 540
  541 FEDRCHFVAD VTESIREATE MEQVRLEMEM EQHTTTTIRP DNQRDSGLPD MDESMKLSNG 600
  601 SNSSAGSSNS STNGVNNSSF RRLSFNSLDS GVVEEHLDAC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..184] MSA 5.211993 View MSA. No confident structure predictions are available.
    2 View Details [185..447] PSI-BLAST 61.522879 SEC7 DOMAIN OF THE ARF EXCHANGE FACTOR ARNO WITH BREFELDIN A-SENSITIZING MUTATIONS
    3 View Details [448..640] PSI-BLAST 14.221849 Grp1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • enzyme regulator activity
    		•  0.33175950121636 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.31803821430449 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.31764113391724 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.19174216196088 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  0.597587183571285 bayes_pls_golite062009
  • protein binding
    		•  0.29116370406325 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle