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Protein Overview: UQCRQ

General Information:
Name(s) found: UQCRQ [HGNC (HUGO)]
Description(s) found:
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  • gi|83367083|ref|NP_055217.2| ubiquinol-cytochrome c reductase, complex III subunit VII [Homo sapiens] [NCBI NR]
  • gi|58477802|gb|AAH90048.1| Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa [Homo sapiens] [NCBI NR]
  • gi|20141846|sp|O14949.4|QCR8_HUMAN RecName: Full=Cytochrome b-c1 complex subunit 8; AltName: Full=Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; AltName: Full=Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; AltName: Fu [NCBI NR]
  • gi|12655079|gb|AAH01390.1| Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa [Homo sapiens] [NCBI NR]
  • ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa [HGNC (HUGO)]
  • Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C - Homo sapiens (Human) [Swiss-Prot]
  • Cytochrome b-c1 complex subunit 8 OS=Homo sapiens GN=UQCRQ PE=1 SV=4 [Swiss-Prot]
  • QP-C protein [Homo sapiens]gi|20141846|sp|O14949|UCRQ_HUMAN Ubiquinol-cytochrome C reductase complex ubiquinone-binding protein QP-C (Ubiquinol-cytochrome C reductase complex 9.5 kDa protein) (Complex III subunit VII) [nrdb_11152004_Chlamydomonas]
  • Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Complex III subunit VII) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • ubiquinol-cytochrome c reductase, complex III subunit VII [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Cytochrome b-c1 complex subunit 8 (Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C) (Ubiquinol-cytochrome c reductase complex 9.5 kDa protein) (Complex III subunit VII) (Complex III subunit 8) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • RecName: Full=Cytochrome b-c1 complex subunit 8; AltName: Full=Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; AltName: Full=Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; AltName: Full=Complex III subunit VIII; AltNam [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=UQCRQ Cytochrome b-c1 complex subunit 8 [human-ipi-250309-contam.fasta]
  • IPI:IPI00024742.7|SWISS-PROT:O14949|ENSEMBL:ENSP00000367934;ENSP00000367936;ENSP00000367939|REFSEQ:NP_055217|H-INV:HIT000266308|VEGA:OTTHUMP00000066205;OTTHUMP00000066206;OTTHUMP00000066207 Tax_Id=9606 Gene_Symbol=UQCRQ Cytochrome b-c1 complex subunit 8 [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=UQCRQ Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C ENSG00000164405 IPI00024742 [drosphohumanreversed.fasta]
  • Tax_Id=9606 Gene_Symbol=UQCRQ Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • cytochrome b-c1 complex subunit 8 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • O14949;Q5FVE2;Q9BV88;Q9T2V7; RecName: Full=Cytochrome b-c1 complex subunit 8; AltName: Full=Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; AltName: Full=Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; AltName: Full=Complex III subunit VIII; AltName: Full=Complex III subunit 8; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Cytochrome b-c1 complex subunit 8 OS=Homo sapiens GN=UQCRQ [011711_HMR.fasta]
  • GeneSymbol=UQCRQ Synonyms=QCR8|QP-C|QPC|UQCR7 cytochrome b-c1 complex subunit 8 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Cytochrome b-c1 complex subunit 8 GN=UQCRQ [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 82 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGREFGNLTR MRHVISYSLS PFEQRAYPHV FTKGIPNVLR RIRESFFRVV PQFVVFYLIY  60
   61 TWGTEEFERS KRKNPAAYEN DK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] PSI-BLAST 34.522879 Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquinol-cytochrome-c reductase activity
    		•  11.4657297014599 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  11.4657297014599 bayes_pls_golite062009
  • ubiquinone binding
    		•  8.14330726546719 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  8.07004376323578 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  5.53710572481351 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  5.38577566963514 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  4.79259194111116 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.78909275746755 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.5536689474984 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.36122531415799 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.96296151827022 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.77517262558965 bayes_pls_golite062009
  • quinone binding
    		•  2.82234066289866 bayes_pls_golite062009
  • binding
    		•  1.40610802203062 bayes_pls_golite062009
  • cofactor binding
    		•  0.937113949001792 bayes_pls_golite062009
  • catalytic activity
    		•  0.442357802307605 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle