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Protein Overview: NFKB2

General Information:
Name(s) found: NFKB2 [HGNC (HUGO)]
Description(s) found:
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  • gi|57790278|gb|AAW56071.1| nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) [Homo sapiens] [NCBI NR]
  • gi|119570091|gb|EAW49706.1| nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100), isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119570089|gb|EAW49704.1| nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100), isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|119570087|gb|EAW49702.1| nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100), isoform CRA_b [Homo sapiens] [NCBI NR]
  • gi|117320531|ref|NP_001070962.1| nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 isoform a [Homo sapiens] [NCBI NR]
  • gi|116242678|sp|Q00653.4|NFKB2_HUMAN RecName: Full=Nuclear factor NF-kappa-B p100 subunit; AltName: Full=DNA-binding factor KBF2; AltName: Full=H2TF1; AltName: Full=Lymphocyte translocation chromosome 10; AltName: Full=Oncogene Lyt-10; Short=Lyt10; Contai [NCBI NR]
  • gi|10178313|emb|CAC08399.1| nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) [Homo sapiens] [NCBI NR]
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) [HGNC (HUGO)]
  • Nuclear factor NF-kappa-B p100 subunit OS=Homo sapiens GN=NFKB2 PE=1 SV=4 [Swiss-Prot]
  • bA18I14.2.1 (nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) isoform 1) [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 Splice Isoform 1 of Nuclear factor NF-kappa-B p100 subunit [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100), isoform CRA_b [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=NFKB2 Isoform 1 of Nuclear factor NF-kappa-B p100 subunit [human-ipi-250309-contam.fasta]
  • IPI:IPI00845373.1|SWISS-PROT:Q00653-1|ENSEMBL:ENSP00000189444;ENSP00000358983;ENSP00000393635|REFSEQ:NP_001070962|VEGA:OTTHUMP00000020371;OTTHUMP00000059136 Tax_Id=9606 Gene_Symbol=NFKB2 Isoform 1 of Nuclear factor NF-kappa-B p100 subunit [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Isoform 1 of Nuclear factor NF-kappa-B p100 subunit [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • nuclear factor NF-kappa-B p100 subunit isoform a [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q00653;Q04860;Q9BU75;Q9H471;Q9H472; RecName: Full=Nuclear factor NF-kappa-B p100 subunit; AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; AltName: Full=DNA-binding factor KBF2; AltName: Full=H2TF1; AltName: Full=Lymphocyte translocation chromosome 10 protein; AltName: Full=Oncogene Lyt-10; Contains: RecName: Full=Nuclear factor NF-kappa-B p52 subunit; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Nuclear factor NF-kappa-B p100 subunit OS=Homo sapiens GN=NFKB2 [011711_HMR.fasta]
  • IPI:IPI00845373.1|SWISS-PROT:Q00653-1|TREMBL:D3DR83|ENSEMBL:ENSP00000189444;ENSP00000358983;ENSP00000393635|REFSEQ:NP_001070962|VEGA:OTTHUMP00000020371;OTTHUMP00000059136 Tax_Id=9606 Gene_Symbol=NFKB2 Isoform 1 of Nuclear factor NF-kappa-B p100 subunit [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=NFKB2 Synonyms=LYT-10|LYT10|p52 nuclear factor NF-kappa-B p100 subunit isoform a [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00845373.1|SWISS-PROT:Q00653-1|ENSEMBL:ENSP00000189444;ENSP00000358983|REFSEQ:NP_001070962|VEGA:OTTHUMP00000020371;OTTHUMP00000059136 Tax_Id=9606 Gene_Symbol=NFKB2 Isoform 1 of Nuclear factor NF-kappa-B p100 subunit [ipi.HUMAN.20110912.fasta]
  • Nuclear factor NF-kappa-B p100 subunit GN=NFKB2 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 900 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESCYNPGLD GIIEYDDFKL NSSIVEPKEP APETADGPYL VIVEQPKQRG FRFRYGCEGP  60
   61 SHGGLPGASS EKGRKTYPTV KICNYEGPAK IEVDLVTHSD PPRAHAHSLV GKQCSELGIC 120
  121 AVSVGPKDMT AQFNNLGVLH VTKKNMMGTM IQKLQRQRLR SRPQGLTEAE QRELEQEAKE 180
  181 LKKVMDLSIV RLRFSAFLRA SDGSFSLPLK PVISQPIHDS KSPGASNLKI SRMDKTAGSV 240
  241 RGGDEVYLLC DKVQKDDIEV RFYEDDENGW QAFGDFSPTD VHKQYAIVFR TPPYHKMKIE 300
  301 RPVTVFLQLK RKRGGDVSDS KQFTYYPLVE DKEEVQRKRR KALPTFSQPF GGGSHMGGGS 360
  361 GGAAGGYGGA GGGGSLGFFP SSLAYSPYQS GAGPMGCYPG GGGGAQMAAT VPSRDSGEEA 420
  421 AEPSAPSRTP QCEPQAPEML QRAREYNARL FGLAQRSARA LLDYGVTADA RALLAGQRHL 480
  481 LTAQDENGDT PLHLAIIHGQ TSVIEQIVYV IHHAQDLGVV NLTNHLHQTP LHLAVITGQT 540
  541 SVVSFLLRVG ADPALLDRHG DSAMHLALRA GAGAPELLRA LLQSGAPAVP QLLHMPDFEG 600
  601 LYPVHLAVRA RSPECLDLLV DSGAEVEATE RQGGRTALHL ATEMEELGLV THLVTKLRAN 660
  661 VNARTFAGNT PLHLAAGLGY PTLTRLLLKA GADIHAENEE PLCPLPSPPT SDSDSDSEGP 720
  721 EKDTRSSFRG HTPLDLTCST KVKTLLLNAA QNTMEPPLTP PSPAGPGLSL GDTALQNLEQ 780
  781 LLDGPEAQGS WAELAERLGL RSLVDTYRQT TSPSGSLLRS YELAGGDLAG LLEALSDMGL 840
  841 EEGVRLLRGP ETRDKLPSTA EVKEDSAYGS QSVEQEAEKL GPPPEPPGGL CHGHPQPQVH 900
  901

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle