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Protein Overview: PNCB_ECOLI

General Information:
Name(s) found: PNCB_ECOLI [Swiss-Prot]
Description(s) found:
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  • pir||JQ0756 nicotinate phosphoribosyltransferase (EC 2.4.2.11) - Escherichia coli (strain K-12) [NCBI NR]
  • gi|147307|gb|AAA24400.1| nicotinic acid phosphoribosyl transferase (pncB) (EC 2.4.2.11) [NCBI NR]
  • gi|130366|sp|P18133.3|PNCB_ECOLI RecName: Full=Nicotinate phosphoribosyltransferase; Short=NAPRTase [NCBI NR]
  • Nicotinate phosphoribosyltransferase (EC 2.4.2.11) (NAPRTase) - Escherichia coli [Swiss-Prot]
  • nicotinate phosphoribosyltransferase [Escherichia coli K12]gi|1787162|gb|AAC74017.1| nicotinate phosphoribosyltransferase [Escherichia coli K12]gi|1651456|dbj|BAA35683.1| Nicotinate phosphoribosyltransferase (EC 2.4.2.11) [Escherichia coli K12]gi|96211 [nrdb_11152004_Chlamydomonas]
  • Nicotinate phosphoribosyltransferase (NAPRTase) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • nicotinic acid phosphoribosyl transferase (pncB) (EC 2.4.2.11) [nr-271106-contam.fasta]
  • Nicotinate phosphoribosyltransferase OS=Escherichia coli (strain K12) GN=pncB PE=1 SV=3 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 400 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQFASPVLH SLLDTDAYKL HMQQAVFHHY YDVHVAAEFR CRGDDLLGIY ADAIREQVQA  60
   61 MQHLRLQDDE YQWLSALPFF KADYLNWLRE FRFNPEQVTV SNDNGKLDIR LSGPWREVIL 120
  121 WEVPLLAVIS EMVHRYRSPQ ADVAQALDTL ESKLVDFSAL TAGLDMSRFH LMDFGTRRRF 180
  181 SREVQETIVK RLQQESWFVG TSNYDLARRL SLTPMGTQAH EWFQAHQQIS PDLANSQRAA 240
  241 LAAWLEEYPD QLGIALTDCI TMDAFLRDFG VEFASRYQGL RHDSGDPVEW GEKAIAHYEK 300
  301 LGIDPQSKTL VFSDNLDLRK AVELYRHFSS RVQLSFGIGT RLTCDIPQVK PLNIVIKLVE 360
  361 CNGKPVAKLS DSPGKTICHD KAFVRALRKA FDLPHIKKAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..400] PSI-BLAST 117.0 Crystal Structure of a Nicotinate Phosphoribosyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nicotinate phosphoribosyltransferase activity
    		•  5.75487746784842 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  4.79136593406808 bayes_pls_golite062009
  • nicotinate-nucleotide diphosphorylase (carboxylating) activity
    		•  3.97201856258863 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  3.41342374351311 bayes_pls_golite062009
  • catalytic activity
    		•  2.59603106157451 bayes_pls_golite062009
  • transferase activity
    		•  1.91642626258277 bayes_pls_golite062009
  • binding
    		•  1.73051405037757 bayes_pls_golite062009
  • protein binding
    		•  0.294646489785198 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle