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Protein Overview: METF_AQUAE

General Information:
Name(s) found: METF_AQUAE [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • 5,10-methylenetetrahydrofolate reductase OS=Aquifex aeolicus (strain VF5) GN=metF PE=3 SV=1 [Swiss-Prot]
    • Organism: Aquifex aeolicus VF5
    Length: 296 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIGDILRKG VFSISFEFFP PKTEEGERQL FETIRKLEKL NPTFVSVTYG AGGSTRDRTR  60
   61 NIVQKIHEET NLTVMAHLTC IAHTREELID ILQDYKNIGI ENILALRGDV PRDKPDWRPP 120
  121 KGACKYAKEL VELIRKEFGD WFSIGVASYP EGHPESPNLE WEVKYFKEKV EAGADFSITQ 180
  181 MFFVNDYYYR FVEMCKNAGI DISIIPGIMP ITNFKQIRKF ASLCGATIPQ SLIEKLEKVE 240
  241 DKPEEVKKIG IEFAINQCLD LIEHGVPGLH FYTLNKSDAT LKIYEAIKDK IPARST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..296] PSI-BLAST 101.0 5,10-Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methylenetetrahydrofolate reductase (NADPH) activity
    		•  4.06186780929512 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  2.68101592248617 bayes_pls_golite062009
  • catalytic activity
    		•  2.52571223195289 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  2.5107658029812 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.12352231809478 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  0.973700948497381 bayes_pls_golite062009
  • proline dehydrogenase activity
    		•  0.78752008628955 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle