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Protein Overview: gi|30253522, gi|...

General Information:
Name(s) found: gi|30260201 [NCBI NR]
gi|30253522 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • gi|30260201|ref|NP_842578.1| DNA gyrase subunit A [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30253522|gb|AAP24064.1| DNA gyrase, A subunit [Bacillus anthracis str. Ames] [NCBI NR]
    • Organism: Bacillus anthracis str. Ames
    Length: 823 amino acids

    Gene Ontology:
    Cellular Component: DNA topoisomerase complex (ATP-hydrolyzing) [ISSLink to PubMed article]
    Biological Process: DNA topological change [ISSLink to PubMed article]
    Molecular Function: DNA topoisomerase (ATP-hydrolyzing) activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDNQQQARI REINISHEMR TSFLDYAMSV IVSRALPDVR DGLKPVHRRV LYAMNDLGIT  60
   61 ADKAYKKSAR IVGEVIGKYH PHGDSAVYET MVRMAQDFSQ RYMLVDGHGN FGSVDGDSAA 120
  121 AMRYTEARMS KISMELIRDI SKNTIDYQDN YDGSEREPIV LPARFPNLLV NGTTGIAVGM 180
  181 ATNIPPHQLG EVIDGVLALS HNPDITIAEL MECIPGPDFP TAGLILGRSG IRRAYETGRG 240
  241 SIILRAKVEI EEKSNGKQSI IVTELPYQVN KARLIEKIAE LVRDKKIEGI TDLRDESDRN 300
  301 GMRIVMEVRR DANANVLLNN LYKHTALQTS FGINMLSLVN GEPQVLNLKQ NLYHYLEHQK 360
  361 VVIRRRTAYE LEKAEARAHI LEGLRIALDH LDEVITLIRS SKTAEIAKQG LMERFGLSEK 420
  421 QAQAILDMRL QRLTGLEREK IEQEYQDLMK LIAELKAILA DEEKVLEIIR EELTEVKERF 480
  481 NDKRRTEITI GGMESIEDED LIPEQNIAIT LTHNGYIKRL PASTYKTQNR GGRGVQGMGT 540
  541 NDDDFVEHLL TTSTHDHILF FTNKGKVYRT KGYEIPEYSR TAKGIPIINL LGVDKGEWIN 600
  601 AIIPIREFGD DEFLFFTTKQ GISKRTPLSS FANIRTNGLI AISLREEDEV ISVRLTSGDK 660
  661 DIIVGTSNGM LIRFNEQDVR SMGRNAAGVK AITLGEEDQV VGMEIVEEDV NVLIVTKNGY 720
  721 GKRTPIDEYR LQSRGGKGLK TCNITDKNGK LVAVKSVTGE EDIMLITAAG VIIRMPVDQI 780
  781 SQMGRNTQGV RLIRLEDEQE VATVAKAQKD DEEETSEEVS SEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..491] PSI-BLAST 1000.0 59KDA FRAGMENT OF GYRASE A FROM E. COLI
    2 View Details [492..823] PSI-BLAST 108.0 A Superhelical Spiral in Escherichia coli DNA Gyrase A C-terminal Domain Imparts Unidirectional Supercoiling Bias

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA topoisomerase activity
    		•  16.1862836613251 bayes_pls_golite062009
  • DNA topoisomerase (ATP-hydrolyzing) activity
    		•  15.3845248199845 bayes_pls_golite062009
  • isomerase activity
    		•  11.5598219279347 bayes_pls_golite062009
  • DNA binding
    		•  4.42972615310468 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.21774496265744 bayes_pls_golite062009
  • binding
    		•  3.95084202265591 bayes_pls_golite062009
  • catalytic activity
    		•  1.83123392049501 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.17291817800492 bayes_pls_golite062009
  • protein binding
    		•  0.0229806746449869 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle