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Protein Overview: gi|30253839, gi|...

General Information:
Name(s) found: gi|30260471 [NCBI NR]
gi|30253839 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • gi|30260471|ref|NP_842848.1| bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30253839|gb|AAP24334.1| phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bacillus anthracis str. Ames] [NCBI NR]
    • Organism: Bacillus anthracis str. Ames
    Length: 511 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: purine ribonucleotide biosynthetic process [ISS]
    Molecular Function: IMP cyclohydrolase activity [ISS]
    phosphoribosylaminoimidazolecarboxamide formyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKRALVSVS DKTGVVEFVK GLLEQGIEVI STGGTKKLLE ENGLQVIGIS EVTGFPEIMD  60
   61 GRVKTLHPNI HGGLLAVRDN ETHVAQMNEL GMEPIDFVVV NLYPFKETIA KPDVTFADAI 120
  121 ENIDIGGPTM IRSAAKNHKF VSVIVDPVDY DVVLAELKEN GEVAEETKRK LAAKVFRHTA 180
  181 AYDALISNYL TEQMGEESPE TLTVTFEKKQ DLRYGENPHQ KATFYKAPFA ATSSVAYAEQ 240
  241 LHGKELSYNN INDADAALSI VKEFTEPAVV AVKHMNPCGV GVGTDIHEAY TRAYEADPVS 300
  301 IFGGIIAANR EIDKATAEKL HEIFLEIIIA PSFSKEALEV LQSKKNLRLL TVNIEKATSA 360
  361 SKKLTSVQGG LLVQEEDTLS LDESTISIPT KREPSEQEWK DLKLAWKVVK HVKSNAIVLA 420
  421 KDDMTIGVGA GQMNRVGSAK IAITQAGEKA QGSALASDAF FPMPDTVEEA AKAGITAIIQ 480
  481 PGGSIRDEDS IKVADTYGIA MVFTGVRHFK H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..511] PSI-BLAST 1000.0 Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • IMP cyclohydrolase activity
    		•  2.44338227123463 bayes_pls_golite062009
  • phosphoribosylaminoimidazolecarboxamide formyltransferase activity
    		•  2.17104645465987 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  1.79965948308471 bayes_pls_golite062009
  • catalytic activity
    		•  1.70756445127105 bayes_pls_golite062009
  • hydroxymethyl-, formyl- and related transferase activity
    		•  1.51378035087272 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  1.19388272840449 bayes_pls_golite062009
  • deaminase activity
    		•  1.16510523659661 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.03324558866637 bayes_pls_golite062009
  • cytidine deaminase activity
    		•  0.870445440530128 bayes_pls_golite062009
  • binding
    		•  0.46651845554048 bayes_pls_golite062009
  • hydrolase activity
    		•  0.339145951258927 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle