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Protein Overview: THYX_GEOSL

General Information:
Name(s) found: THYX_GEOSL [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • Thymidylate synthase ThyX OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=thyX PE=3 SV=1 [Swiss-Prot]
    • Organism: Geobacter sulfurreducens PCA
    Length: 232 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: 2'-deoxyribonucleotide biosynthetic process [ISSLink to PubMed article]
    Molecular Function: thymidylate synthase (FAD) activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIALLQHTP DPEAAVALAA RLCYASVGID ELREKLSASD VTAFLDKIMS LGHQSVLEHA  60
   61 SFTFGIEGIS RAASHQLVRH RIASYSQQSQ RYVTFRGDGF PRVVPGSVSA TEKRRQVFES 120
  121 AMQACADAYR ALVDDGVPAE DARFVLPNAA ETKIIVTMNA RELIHFFGLR CCERAQWEIR 180
  181 ALAVEMLRLV KGVAPTIFRD AGPGCLTGPC PEGGMTCGKA AEVKRLFREM SI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..232] PSI-BLAST 56.69897 Crystal structure of Mycobacterium tuberculosis Flavin dependent thymidylate synthase (Mtb ThyX) in the presence of co-factor FAD and substrate analog 5-Bromo-2'-Deoxyuridine-5'-Monophosphate (BrdUMP)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.67

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle