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Protein Overview: HLDE_SHEON

General Information:
Name(s) found: HLDE_SHEON [Swiss-Prot]
Description(s) found:
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  • gi|24375241|ref|NP_719284.1| bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24350035|gb|AAN56728.1|AE015808_4 ADP-heptose synthase [Shewanella oneidensis MR-1] [NCBI NR]
  • Bifunctional protein HldE OS=Shewanella oneidensis (strain MR-1) GN=hldE PE=3 SV=1 [Swiss-Prot]
  • ADP-heptose synthase [Shewanella oneidensis MR-1]gi|24350035|gb|AAN56728.1| ADP-heptose synthase [Shewanella oneidensis MR-1]gi|54036043|sp|Q8EAZ2|HLDE_SHEON Bifunctional protein hldE [Includes: D-beta-D-heptose 7-phosphate kinase (D-beta-D-heptose 7-ph [nrdb_11152004_Chlamydomonas]
  • ADP-heptose synthase [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
    • Organism: Shewanella oneidensis MR-1
    Length: 476 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: lipopolysaccharide core region biosynthetic process [ISSLink to PubMed article]
    Molecular Function: catalytic activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVSLPAFEK AKVLVVGDVM LDRYWVGPTG RISPEAPVPV VKINQVEDRP GGAANVALNI  60
   61 ATLGGQVQLA GLVGEDDTAK ALTLGVQALG VEPQWLNIAD KPTITKLRVL SRNQQLIRLD 120
  121 FEESFDKQDS ARLLKQSEAL LDSVDVVVLS DYAKGAIDNP RDFIALARSK GVKVLVDPKG 180
  181 SDFSRYHGAS LITPNMSEFE AVVGAVTSEA DLLEKARGLL NKYQFDAILV TRSEKGMTLV 240
  241 TANAPELHIP TVAREVYDVT GAGDTVISAL ATSLAAGAEL AQACAIANTA AGVVVGKLGT 300
  301 STVSRIELIE ALALHHGESG FGVVSEDQLA YALEQAKLRG ERVVMTNGCF DILHAGHVSY 360
  361 LKQAKALGDR LIVAVNDDAS VKRLKGEGRP VNQVDRRMAV LAGLASVDWV VPFSEDTPQR 420
  421 IIARLLPDLL VKGGDYKVED IAGGAEVISA GGQVQVLGFE DGISTTAIIQ NIMAKQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..323] PSI-BLAST 49.09691 Ribokinase
    2 View Details [324..476] PSI-BLAST 27.69897 CTP:glycerol-3-phosphate cytidylyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.11518580948187 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  1.99025603598964 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.69918601153494 bayes_pls_golite062009
  • transferase activity
    		•  1.65599843675995 bayes_pls_golite062009
  • kinase activity
    		•  1.6060752218324 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.143446029424335 bayes_pls_golite062009
    2
    Term Confidence Notes
  • catalytic activity
    		•  2.74718220535323 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  2.19141941108903 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  2.19141941108903 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  2.17852738923841 bayes_pls_golite062009
  • ligase activity
    		•  1.15322915814026 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle