Protein Overview: TPS2_YEAST

General Information:
Name(s) found:	TPS2_YEAST [Swiss-Prot]
Description(s) found:	Trehalose-phosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPS2 PE=1 SV=3 [Swiss-Prot]
Organism:	Saccharomyces cerevisiae S288c
Length:	896 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTTAQDNSP KKRQRIINCV TQLPYKIQLG ESNDDWKISA TTGNSALFSS LEYLQFDSTE  60
   61 YEQHVVGWTG EITRTERNLF TREAKEKPQD LDDDPLYLTK EQINGLTTTL QDHMKSDKEA 120
  121 KTDTTQTAPV TNNVHPVWLL RKNQSRWRNY AEKVIWPTFH YILNPSNEGE QEKNWWYDYV 180
  181 KFNEAYAQKI GEVYRKGDII WIHDYYLLLL PQLLRMKFND ESIIIGYFHH APWPSNEYFR 240
  241 CLPRRKQILD GLVGANRICF QNESFSRHFV SSCKRLLDAT AKKSKNSSNS DQYQVSVYGG 300
  301 DVLVDSLPIG VNTTQILKDA FTKDIDSKVL SIKQAYQNKK IIIGRDRLDS VRGVVQKLRA 360
  361 FETFLAMYPE WRDQVVLIQV SSPTANRNSP QTIRLEQQVN ELVNSINSEY GNLNFSPVQH 420
  421 YYMRIPKDVY LSLLRVADLC LITSVRDGMN TTALEYVTVK SHMSNFLCYG NPLILSEFSG 480
  481 SSNVLKDAIV VNPWDSVAVA KSINMALKLD KEEKSNLESK LWKEVPTIQD WTNKFLSSLK 540
  541 EQASSNDDME RKMTPALNRP VLLENYKQAK RRLFLFDYDG TLTPIVKDPA AAIPSARLYT 600
  601 ILQKLCADPH NQIWIISGRD QKFLNKWLGG KLPQLGLSAE HGCFMKDVSC QDWVNLTEKV 660
  661 DMSWQVRVNE VMEEFTTRTP GSFIERKKVA LTWHYRRTVP ELGEFHAKEL KEKLLSFTDD 720
  721 FDLEVMDGKA NIEVRPRFVN KGEIVKRLVW HQHGKPQDML KGISEKLPKD EMPDFVLCLG 780
  781 DDFTDEDMFR QLNTIETCWK EKYPDQKNQW GNYGFYPVTV GSASKKTVAK AHLTDPQQVL 840
  841 ETLGLLVGDV SLFQSAGTVD LDSRGHVKNS ESSLKSKLAS KAYVMKRSAS YTGAKV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..120]	deduced	N/A	No confident structure predictions are available.
2	View Details	[121..317] [524..545]	ORFEUS	13.39	UDP-N-acetylglucosamine 2-epimerase
3	View Details	[318..523]	ORFEUS	13.39	UDP-N-acetylglucosamine 2-epimerase
4	View Details	[546..896]	MSA	25.886997	View MSA. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	11.2045941324603	bayes_pls_golite062009
glucosyltransferase activity	8.25064561355471	bayes_pls_golite062009
UDP-glucosyltransferase activity	8.0463972704113	bayes_pls_golite062009
trehalose-phosphatase activity	7.58500038184065	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	3.70184884300914	bayes_pls_golite062009
catalytic activity	2.65148466065976	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.62403914335522	bayes_pls_golite062009
transferase activity	2.18054407163329	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.13085705769565	bayes_pls_golite062009
binding	0.86799881302731	bayes_pls_golite062009
carbohydrate phosphatase activity	0.78952375993773	bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity	0.690032302126686	bayes_pls_golite062009
glycogen phosphorylase activity	0.607220464589157	bayes_pls_golite062009
phosphorylase activity	0.296436712681472	bayes_pls_golite062009
mannosyltransferase activity	0.253888301381021	bayes_pls_golite062009

2

Term	Confidence	Notes
trehalose-phosphatase activity	3.78859922218487	bayes_pls_golite062009
catalytic activity	1.55296860681783	bayes_pls_golite062009
binding	0.54369553186176	bayes_pls_golite062009
hydrolase activity	0.385402333062566	bayes_pls_golite062009
nucleic acid binding	0.263520144636139	bayes_pls_golite062009
phosphatase activity	0.159899259988948	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.103902756538853	bayes_pls_golite062009
DNA binding	0.0142681844140111	bayes_pls_golite062009

3

No functions predicted.

4

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle