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Protein Overview: SLA1_YEAST

General Information:
Name(s) found: SLA1_YEAST [Swiss-Prot]
Description(s) found:
  • Actin cytoskeleton-regulatory complex protein SLA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLA1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1244 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVFLGIYRA VYAYEPQTPE ELAIQEDDLL YLLQKSDIDD WWTVKKRVIG SDSEEPVGLV  60
   61 PSTYIEEAPV LKKVRAIYDY EQVQNADEEL TFHENDVFDV FDDKDADWLL VKSTVSNEFG 120
  121 FIPGNYVEPE NGSTSKQEQA PAAAEAPAAT PAAAPASAAV LPTNFLPPPQ HNDRARMMQS 180
  181 KEDQAPDEDE EGPPPAMPAR PTATTETTDA TAAAVRSRTR LSYSDNDNDD EEDDYYYNSN 240
  241 SNNVGNHEYN TEYHSWNVTE IEGRKKKKAK LSIGNNKINF IPQKGTPHEW SIDKLVSYDN 300
  301 EKKHMFLEFV DPYRSLELHT GNTTTCEEIM NIIGEYKGAS RDPGLREVEM ASKSKKRGIV 360
  361 QYDFMAESQD ELTIKSGDKV YILDDKKSKD WWMCQLVDSG KSGLVPAQFI EPVRDKKHTE 420
  421 STASGIIKSI KKNFTKSPSR SRSRSRSKSN ANASWKDDEL QNDVVGSAAG KRSRKSSLSS 480
  481 HKKNSSATKD FPNPKKSRLW VDRSGTFKVD AEFIGCAKGK IHLHKANGVK IAVAADKLSN 540
  541 EDLAYVEKIT GFSLEKFKAN DGSSSRGTDS RDSERERRRR LKEQEEKERD RRLKERELYE 600
  601 LKKARELLDE ERSRLQEKEL PPIKPPRPTS TTSVPNTTSV PPAESSNNNN SSNKYDWFEF 660
  661 FLNCGVDVSN CQRYTINFDR EQLTEDMMPD INNSMLRTLG LREGDIVRVM KHLDKKFGRE 720
  721 NIASIPTNAT GNMFSQPDGS LNVATSPETS LPQQLLPQTT SPAQTAPSTS AETDDAWTVK 780
  781 PASKSESNLL SKKSEFTGSM QDLLDLQPLE PKKAAASTPE PNLKDLEPVK TGGTTVPAAP 840
  841 VSSAPVSSAP APLDPFKTGG NNILPLSTGF VMMPMITGGD MLPMQRTGGF VVPQTTFGMQ 900
  901 SQVTGGILPV QKTGNGLIPI SNTGGAMMPQ TTFGAAATVL PLQKTGGGLI PIATTGGAQF 960
  961 PQTSFNVQGQ QQLPTGSILP VQKTANGLIS ANTGVSMPTV QRTGGTMIPQ TSFGVSQQLT1020
 1021 GGAMMTQPQN TGSAMMPQTS FNAVPQITGG AMMPQTSFNA LPQVTGGAMM PLQRTGGALN1080
 1081 TFNTGGAMIP QTSFSSQAQN TGGFRPQSQF GLTLQKTGGI APLNQNQFTG GAMNTLSTGG1140
 1141 VLQQQQPQTM NTFNTGGVMQ ELQMMTTFNT GGAMQQPQMM NTFNTDGIMQ QPQMMNTFNT1200
 1201 GGAMQQPQQQ ALQNQPTGFG FGNGPQQSRQ ANIFNATASN PFGF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] ORFEUS 11.86 Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains
    2 View Details [74..167] PSI-BLAST 50.69897 Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains
    3 View Details [168..339] deduced N/A No confident structure predictions are available.
    4 View Details [340..415] PSI-BLAST 112.9897 Fyn proto-oncogene tyrosine kinase, SH3 domain; Tyrosine kinase Fyn
    5 View Details [416..502] PSI-BLAST 112.9897 Fyn proto-oncogene tyrosine kinase, SH3 domain; Tyrosine kinase Fyn
    6 View Details [503..791] deduced N/A No confident structure predictions are available.
    7 View Details [792..1063] ORFEUS 9.96 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
    8 View Details [1064..1121] ORFEUS 9.96 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
    9 View Details [1122..1244] ORFEUS 14.72 No description for 1ldvA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  4.67602289179099 bayes_pls_golite062009
  • actin binding
    		•  4.45930345274274 bayes_pls_golite062009
  • actin filament binding
    		•  3.61541643295162 bayes_pls_golite062009
  • binding
    		•  2.92117841029443 bayes_pls_golite062009
  • protein binding
    		•  2.10925438883926 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  4.67602289179099 bayes_pls_golite062009
  • actin binding
    		•  4.45930345274274 bayes_pls_golite062009
  • actin filament binding
    		•  3.61541643295162 bayes_pls_golite062009
  • binding
    		•  2.97936662084105 bayes_pls_golite062009
  • protein binding
    		•  2.16879701585602 bayes_pls_golite062009
  • signal transducer activity
    		•  0.485790902947642 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.485790902947642 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.230308623372106 bayes_pls_golite062009
  • molecular adaptor activity
    		•  0.211510977251932 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle