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Protein Overview: SEC18_YEAST

General Information:
Name(s) found: SEC18_YEAST [Swiss-Prot]
Description(s) found:
  • Vesicular-fusion protein SEC18 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC18 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 758 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKIPGFGKA AANHTPPDMT NMDTRTRHLK VSNCPNNSYA LANVAAVSPN DFPNNIYIII  60
   61 DNLFVFTTRH SNDIPPGTIG FNGNQRTWGG WSLNQDVQAK AFDLFKYSGK QSYLGSIDID 120
  121 ISFRARGKAV STVFDQDELA KQFVRCYESQ IFSPTQYLIM EFQGHFFDLK IRNVQAIDLG 180
  181 DIEPTSAVAT GIETKGILTK QTQINFFKGR DGLVNLKSSN SLRPRSNAVI RPDFKFEDLG 240
  241 VGGLDKEFTK IFRRAFASRI FPPSVIEKLG ISHVKGLLLY GPPGTGKTLI ARKIGTMLNA 300
  301 KEPKIVNGPE ILSKYVGSSE ENIRNLFKDA EAEYRAKGEE SSLHIIIFDE LDSVFKQRGS 360
  361 RGDGTGVGDN VVNQLLAKMD GVDQLNNILV IGMTNRKDLI DSALLRPGRF EVQVEIHLPD 420
  421 EKGRLQIFDI QTKKMRENNM MSDDVNLAEL AALTKNFSGA EIEGLVKSAS SFAINKTVNI 480
  481 GKGATKLNTK DIAKLKVTRE DFLNALNDVT PAFGISEEDL KTCVEGGMML YSERVNSILK 540
  541 NGARYVRQVR ESDKSRLVSL LIHGPAGSGK TALAAEIALK SGFPFIRLIS PNELSGMSES 600
  601 AKIAYIDNTF RDAYKSPLNI LVIDSLETLV DWVPIGPRFS NNILQMLKVA LKRKPPQDRR 660
  661 LLIMTTTSAY SVLQQMDILS CFDNEIAVPN MTNLDELNNV MIESNFLDDA GRVKVINELS 720
  721 RSCPNFNVGI KKTLTNIETA RHDEDPVNEL VELMTQSA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..103] PSI-BLAST 1136.522879 N-terminal domain of NSF-N, NSF-Nn; C-terminal domain of NSF-N, NSF-Nc
    2 View Details [104..218] PSI-BLAST 1136.522879 N-terminal domain of NSF-N, NSF-Nn; C-terminal domain of NSF-N, NSF-Nc
    3 View Details [219..410] PSI-BLAST 5.39794 Holliday junction helicase RuvB
    4 View Details [411..506] ORFEUS 14.82 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    5 View Details [507..690] PSI-BLAST 495.38764 Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein
    6 View Details [691..758] PSI-BLAST 495.38764 Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle