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Protein Overview: RKM1_YEAST

General Information:
Name(s) found: RKM1_YEAST [Swiss-Prot]
Description(s) found:
  • Ribosomal lysine N-methyltransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RKM1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 583 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDALKALL QWGASFGVIV PEELKFLYTD LKGIICVCEK DIDNPSIKIP PEIVISRNLP  60
   61 MKFFGLSEST KNINGWLKLF FAKIKFDRDN DTIVDNVRVN DKFKPYLDAL PSRLNSPLVW 120
  121 NPSELKRLSS TNIGNSIHEK FEGIFKEWFE LVSSSDMFDL ERVADDVQTF HNLDELTYEA 180
  181 LYEKILKITE LQRPTIWYSF PAFLWSHLIF ISRAFPEYVL NRNCPDNSIV LLPIVDLLNH 240
  241 DYRSKVKWYP ENGWFCYEKI GTASQSRELS NNYGGKGNEE LLSGYGFVLE DNIFDSVALK 300
  301 VKLPLDVVST ILETEPSLKL PLLSDYTTYA FENKDCVQQE KKATRSATDY INGVTYFINI 360
  361 QNEQCLEPLL DLFTYLSKAE EEDLHDLRAR LQGIQMLRNA LQSKLNSITG PPATDDSYAI 420
  421 DPYRVYCADV YTKGQKQILK EALTRLKKLE KTMLSENKHQ LLTMSKILKN DPAFAETELP 480
  481 SLFSNEDGEE VIFESTYDLL ILWILLKTKK NSYPTKYEWV GQQYTNFKQT AYISDDAKAF 540
  541 HTAYFEKQDD VDLAEVDHAI QFVVDNSFTR TSSTTEETIL VRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113]
    [142..274]    		 PSI-BLAST 72.0 RuBisCo LSMT C-terminal, substrate-binding domain; RuBisCo LSMT catalytic domain
    2 View Details [114..141]
    [275..299]
    [401..442]    		 PSI-BLAST 72.0 RuBisCo LSMT C-terminal, substrate-binding domain; RuBisCo LSMT catalytic domain
    3 View Details [300..400]
    [443..512]    		 PSI-BLAST 72.0 RuBisCo LSMT C-terminal, substrate-binding domain; RuBisCo LSMT catalytic domain
    4 View Details [513..583] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • histone methyltransferase activity
    		•  6.20878333364554 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  6.08778683840554 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  5.45106430536252 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  3.98411678860954 bayes_pls_golite062009
  • histone methyltransferase activity (H3-K9 specific)
    		•  3.54138873512018 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.69428385009711 bayes_pls_golite062009
  • methyltransferase activity
    		•  2.33114816345072 bayes_pls_golite062009
  • binding
    		•  2.2675356705139 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  2.25175257044903 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.79964884912488 bayes_pls_golite062009
  • chromatin binding
    		•  1.00298380074254 bayes_pls_golite062009
  • protein binding
    		•  0.938282161933492 bayes_pls_golite062009
  • transferase activity
    		•  0.653108419761009 bayes_pls_golite062009
  • catalytic activity
    		•  0.414641636618101 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.80

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle