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Protein Overview: PPX1_YEAST

General Information:
Name(s) found: PPX1_YEAST [Swiss-Prot]
Description(s) found:
  • Exopolyphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PPX1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 397 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPLRKTVPE FLAHLKSLPI SKIASNDVLT ICVGNESADM DSIASAITYS YCQYIYNEGT  60
   61 YSEEKKKGSF IVPIIDIPRE DLSLRRDVMY VLEKLKIKEE ELFFIEDLKS LKQNVSQGTE 120
  121 LNSYLVDNND TPKNLKNYID NVVGIIDHHF DLQKHLDAEP RIVKVSGSCS SLVFNYWYEK 180
  181 LQGDREVVMN IAPLLMGAIL IDTSNMRRKV EESDKLAIER CQAVLSGAVN EVSAQGLEDS 240
  241 SEFYKEIKSR KNDIKGFSVS DILKKDYKQF NFQGKGHKGL EIGLSSIVKR MSWLFNEHGG 300
  301 EADFVNQCRR FQAERGLDVL VLLTSWRKAG DSHRELVILG DSNVVRELIE RVSDKLQLQL 360
  361 FGGNLDGGVA MFKQLNVEAT RKQVVPYLEE AYSNLEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..251] PSI-BLAST 56.522879 Manganese-dependent inorganic pyrophosphatase (family II)
    2 View Details [252..397] PSI-BLAST 56.522879 Manganese-dependent inorganic pyrophosphatase (family II)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nuclease activity
    		•  2.22762374984422 bayes_pls_golite062009
  • hydrolase activity
    		•  2.11996205929773 bayes_pls_golite062009
  • catalytic activity
    		•  1.78154379547895 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.7679956422453 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.7238398802096 bayes_pls_golite062009
  • binding
    		•  1.52735252886759 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.48438369225803 bayes_pls_golite062009
  • exonuclease activity
    		•  1.4791620684568 bayes_pls_golite062009
  • single-stranded DNA specific exodeoxyribonuclease activity
    		•  1.10404503151762 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.808006273031307 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.792120683260194 bayes_pls_golite062009
  • protein binding
    		•  0.332901114484316 bayes_pls_golite062009
  • inorganic diphosphatase activity
    		•  0.158887418739632 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle