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Protein Overview: MNS1_YEAST

General Information:
Name(s) found: MNS1_YEAST [Swiss-Prot]
Description(s) found:
  • Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MNS1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 549 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNSVGISIA TIVAIIAAIY YVPWYEHFER KSPGAGEMRD RIESMFLESW RDYSKHGWGY  60
   61 DVYGPIEHTS HNMPRGNQPL GWIIVDSVDT LMLMYNSSTL YKSEFEAEIQ RSEHWINDVL 120
  121 DFDIDAEVNV FETTIRMLGG LLSAYHLSDV LEVGNKTVYL NKAIDLGDRL ALAFLSTQTG 180
  181 IPYSSINLHS GQAVKNHADG GASSTAEFTT LQMEFKYLAY LTGNRTYWEL VERVYEPLYK 240
  241 NNDLLNTYDG LVPIYTFPDT GKFGASTIRF GSRGDSFYEY LLKQYLLTHE TLYYDLYRKS 300
  301 MEGMKKHLLA QSKPSSLWYI GEREQGLHGQ LSPKMDHLVC FMGGLLASGS TEGLSIHEAR 360
  361 RRPFFSLSLE RKSDWDLAKG ITDTCYQMYK QSSSGLAPEI VVFNDGNIKQ DGWWRSSVGD 420
  421 FFVKPLDRHN LQRPETVESI MFMYHLSHDH KYREWGAEIA TSFFENTCVD CNDPKLRRFT 480
  481 SLSDCITLPT KKSNNMESFW LAETLKYLYI LFLDEFDLTK VVFNTEAHPF PVLDEEILKS 540
  541 QSLTTGWSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..301]
    [494..549]    		 PSI-BLAST 11000.0 Class I alpha-1;2-mannosidase, catalytic domain
    2 View Details [302..493] PSI-BLAST 11000.0 Class I alpha-1;2-mannosidase, catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • mannosyl-oligosaccharide mannosidase activity
    		•  7.089685350864 bayes_pls_golite062009
  • mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
    		•  6.95179264736435 bayes_pls_golite062009
  • mannosidase activity
    		•  5.20286438265852 bayes_pls_golite062009
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.31319275372149 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  3.65589746311782 bayes_pls_golite062009
  • hydrolase activity
    		•  2.67964748309919 bayes_pls_golite062009
  • binding
    		•  1.49199031708525 bayes_pls_golite062009
  • catalytic activity
    		•  1.31873306707813 bayes_pls_golite062009
  • cation binding
    		•  0.362242764130218 bayes_pls_golite062009
  • metal ion binding
    		•  0.362242764130218 bayes_pls_golite062009
  • protein binding
    		•  0.36081692928767 bayes_pls_golite062009
  • ion binding
    		•  0.355220167272296 bayes_pls_golite062009
  • calcium ion binding
    		•  0.121126738064555 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle