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Protein Overview: MED16_YEAST

General Information:
Name(s) found: MED16_YEAST [Swiss-Prot]
Description(s) found:
  • Mediator of RNA polymerase II transcription subunit 16 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIN4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 974 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLGEHLMSW SKTGIIAYSD SQSSNANICL TFLESINGIN WRFHTPQKYV LHPQLHEVQY  60
   61 QESSSTLSTH STTTSVNGST TAGVGSTPNF GGNSNKSPPQ FFYNISSIHW NNWFSLPGDM 120
  121 LAVCDELGNM TMLITGQRPD RATTYEKLTM VFQDNVYKIY NHVMPLKPVD KLKPMNIERK 180
  181 QTRKEYNTSI LEFRWLTSSK SVIVSQFCAF DSSSNTYRSR AQQVPPYGVY HPPFIKYACL 240
  241 AIRKNGQIDF WYQFSNSKDH KKITLQLLDT SNQRFKDLQW LEFARITPMN DDQCMLITTY 300
  301 SKLSKNISFY KLHVNWNLNA TKPNVLNDPS LKIQFILSTT LDPTDDEGHV LKLENLHVVS 360
  361 KSSIEKDPSP EILVLYNVCD TSKSLVKRYR LAPTQLSAEY LVILKPDLNI DRNNSTNQIF 420
  421 QSRRYNLRRH SDIVLDKKVT LITSEMFDAF VSFYFEDGTI ESYNQNDWKL ETERLISQSQ 480
  481 LGKFKNIIAS PLSAGFNYGK LPLPPSVEWM KVSPSMCGVI VKQYNKKWPQ FYAAVQKNYA 540
  541 DPEKDSINAT ALAFGYVKSL HKQISAEDLT IAAKTHILRI SFLDRKRAKE FITTLLKSLY 600
  601 SFFNISPDAP KEIMDKIITS RPLQKIMLLQ LELGSCFSQE NIEEMARVIL YLKNVLFAFN 660
  661 GVARNFHFAI EQISNNSNQQ QNPKLFQTIF SKQDLIHSLI PVAKWFVKFI TYLTQEILIL 720
  721 INDPTNKEYT LVHGIFGAKM SRTLILSILN EIKKVTQIVA KFPETSYPIL NESSTFLKLV 780
  781 LSESPVDFEK FETFLVDVNN KFIALCEQQP SQEREFSLLV KAEIPPEYAK VGDFLLQYAN 840
  841 NAVISHANAA AVYFADTSGL KISNSEFFNP EIFHLLQPLE EGLIIDTDKL PIKNRTSKSF 900
  901 SKLLYDDVTC DKLSVSEISD GKLKRCSRCG SVTRAGNIIS SDKTIVPTSI QTKRWPTMYT 960
  961 RLCICSGMLF EMDG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..457] deduced N/A No confident structure predictions are available.
    2 View Details [458..641]
    [689..773]    		 ORFEUS 7.83 Hemolysin E (HlyE, ClyA, SheA)
    3 View Details [642..688] ORFEUS 7.83 Hemolysin E (HlyE, ClyA, SheA)
    4 View Details [774..974] deduced N/A No confident structure predictions are available.
    5 View Details [691..807] deduced N/A No confident structure predictions are available.
    6 View Details [808..974] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle