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Protein Overview: AP2A_YEAST

General Information:
Name(s) found: AP2A_YEAST [Swiss-Prot]
Description(s) found:
  • AP-2 complex subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APL3 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1025 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRKKTLINS SVSNNNSTIK GLQLFIADLR SAQQAQEQEK RIQSEIVKIK QHFDAAKKKQ  60
   61 GNHDRLGGYQ RKKYVAKLAY IYITSNTTKL NEILFGLEQT VELLKSSIFS EKFIGYMTLE 120
  121 LLYERSEVVA KVNDEVNYQL MKDLSSSDDN FVMLALNFVG VVGELTNRLA YNDDITTGVF 180
  181 KILRSPTSSI YLKKKSALSF LALLKSNHSI LTEDLQRKQL WIQRILSLLD DTENYRLTLA 240
  241 TIPLIEFIAK YIDPSYCTRL LPQLTEILYN CVVVGTSRSS DNQFPLEYTF ANMPNPWLIT 300
  301 KVVSLLSILI ASPTERDSGS LLQTNNIDNE LLNKLRKCVS VAIELGTRQA QDPMERIVQN 360
  361 TVLFSLINFA SKLDPSDEAI SNSVTALCSL LTSKEINIRY LTLDSLVKLC SSSGKPAIDA 420
  421 VRYKNLDMIF HLLNTERDSS IVRKVVDLLY TFTDVENVKI IVDGLLQYIL SPKNLAEPQI 480
  481 KSDIAVKIAI LTEKYATDIN WFVIISLQLL SLTSNTTIND DEIWQRLCQI VVNNPSLHRI 540
  541 TCERLVDYLC KKQASEAIIK AAAFLLGEYS SLITDRISSA NLFTLFAEKY FSAPNVAKAM 600
  601 ILTTMIKLYK TSPEIGSNVI KFFQLELNSL DIELQTRSFE YLNIIQLAKV NGNTDILQIL 660
  661 FEPMPPFNSK SNPLLKRLGS LPASAGSTTL INTPSEASSS TPDLLSKRAN SSRSIMVPMP 720
  721 PPSRRNTIDD VNSKISSSED FSGKDSYYSR QILAPNWREG FTRMISHKQG VLFTSSLMKV 780
  781 FYRITTPDAQ QPYVFHISLA FINLTEWEIT GLSTQIIPSK TQGNPEYLIM NINTPSTATI 840
  841 GPHKRAEQSY EVSIRKPFDV EDSPILAIHF KCGGSTNTIN LKTAIGMTTT LISSDVNPSM 900
  901 HLNLAQFISR WKTLSDALGK EGEYQKSGIK LNKDFRKVET ISLEDGLLLL TQTVKRLGFD 960
  961 IVDQTSVRST LFVSGIIHTK SEGNFGCLMK IQYQVNGTVN VTCKTTTAGP LAKYIVECIK1020
 1021 NVLTK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] PSI-BLAST 608.0 Adaptin alpha C subunit N-terminal fragment
    2 View Details [136..219] PSI-BLAST 608.0 Adaptin alpha C subunit N-terminal fragment
    3 View Details [220..381] PSI-BLAST 608.0 Adaptin alpha C subunit N-terminal fragment
    4 View Details [382..457] PSI-BLAST 608.0 Adaptin alpha C subunit N-terminal fragment
    5 View Details [458..576] PSI-BLAST 608.0 Adaptin alpha C subunit N-terminal fragment
    6 View Details [577..743] deduced N/A Confident ab initio structure predictions are available.
    7 View Details [744..888] PSI-BLAST 120.522879 Alpa-adaptin AP2 ear domain, N-terminal subdomain; Alpa-adaptin AP2, C-terminal subdomain
    8 View Details [889..1025] PSI-BLAST 120.522879 Alpa-adaptin AP2 ear domain, N-terminal subdomain; Alpa-adaptin AP2, C-terminal subdomain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle