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Protein Overview: FUMH_YEAST

General Information:
Name(s) found: FUMH_YEAST [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Fumarate hydratase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FUM1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 488 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRFTNCSCK TFVKSSYKLN IRRMNSSFRT ETDAFGEIHV PADKYWGAQT QRSFQNFKIG  60
   61 GARERMPLPL VHAFGVLKKS AAIVNESLGG LDPKISKAIQ QAADEVASGK LDDHFPLVVF 120
  121 QTGSGTQSNM NANEVISNRA IEILGGKIGS KQVHPNNHCN QSQSSNDTFP TVMHIAASLQ 180
  181 IQNELIPELT NLKNALEAKS KEFDHIVKIG RTHLQDATPL TLGQEFSGYV QQVENGIQRV 240
  241 AHSLKTLSFL AQGGTAVGTG LNTKPGFDVK IAEQISKETG LKFQTAPNKF EALAAHDAIV 300
  301 ECSGALNTLA CSLFKIAQDI RYLGSGPRCG YHELMLPENE PGSSIMPGKV NPTQNEALTQ 360
  361 VCVQVMGNNA AITFAGSQGQ FELNVFKPVM IANLLNSIRL ITDAAYSFRV HCVEGIKANE 420
  421 PRIHELLTKS LMLVTALNPK IGYDAASKVA KNAHKKGITL KESALELGVL TEKEFDEWVV 480
  481 PEHMLGPK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..193]
    [232..314]
    [358..407]    		 PSI-BLAST 11000.0 Fumarase
    2 View Details [194..231]
    [315..357]
    [408..428]    		 PSI-BLAST 11000.0 Fumarase
    3 View Details [429..488] PSI-BLAST 11000.0 Fumarase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • fumarate hydratase activity
    		•  4.22589182982073 bayes_pls_golite062009
  • catalytic activity
    		•  2.51282259572665 bayes_pls_golite062009
  • lyase activity
    		•  2.31268471569846 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  2.2046475419807 bayes_pls_golite062009
  • histidine ammonia-lyase activity
    		•  0.948129236753279 bayes_pls_golite062009
  • amidine-lyase activity
    		•  0.901614580251298 bayes_pls_golite062009
  • binding
    		•  0.854855116369286 bayes_pls_golite062009
  • argininosuccinate lyase activity
    		•  0.617974375213548 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.491229595527877 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle