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Protein Overview: IF6_YEAST

General Information:
Name(s) found: IF6_YEAST [Swiss-Prot]
Description(s) found:
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  • Eukaryotic translation initiation factor 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TIF6 PE=1 SV=1 [Swiss-Prot]
  • Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits [Saccharomyces cerevisiae] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 245 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATRTQFENS NEIGVFSKLT NTYCLVAVGG SENFYSAFEA ELGDAIPIVH TTIAGTRIIG  60
   61 RMTAGNRRGL LVPTQTTDQE LQHLRNSLPD SVKIQRVEER LSALGNVICC NDYVALVHPD 120
  121 IDRETEELIS DVLGVEVFRQ TISGNILVGS YCSLSNQGGL VHPQTSVQDQ EELSSLLQVP 180
  181 LVAGTVNRGS SVVGAGMVVN DYLAVTGLDT TAPELSVIES IFRLQDAQPE SISGNLRDTL 240
  241 IETYS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..245] PSI-BLAST 1301.0 Ribosome anti-association factor eIF6 (aIF6)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  2.82313826209658 bayes_pls_golite062009
  • ribosomal large subunit binding
    		•  2.29551693750603 bayes_pls_golite062009
  • binding
    		•  1.48640777619976 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.14138534491569 bayes_pls_golite062009
  • hydrolase activity
    		•  1.05437300113124 bayes_pls_golite062009
  • catalytic activity
    		•  0.889920589881492 bayes_pls_golite062009
  • protein binding
    		•  0.21271994410782 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle