Protein Overview: GABT_RAT

General Information:
Name(s) found:	GABT_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|51859450\|gb\|AAH81787.1\| 4-aminobutyrate aminotransferase [Rattus norvegicus] [NCBI NR] gi\|149042606\|gb\|EDL96243.1\| 4-aminobutyrate aminotransferase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|122065191\|sp\|P50554.3\|GABT_RAT RecName: Full=4-aminobutyrate aminotransferase, mitochondrial; AltName: Full=Gamma-amino-N-butyrate transaminase; Short=GABA transaminase; Short=GABA-T; AltName: Full=GABA aminotransferase; Short=GABA-AT; AltName: Full=L- [NCBI NR] 4-aminobutyrate aminotransferase, mitochondrial OS=Rattus norvegicus GN=Abat PE=1 SV=3 [Swiss-Prot] 4-aminobutyrate aminotransferase [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 4-aminobutyrate aminotransferase [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] 4-aminobutyrate aminotransferase, mitochondrial precursor (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (GABA aminotransferase) (GABA-AT) (L-AIBAT) ((S)-3-amino-2-methylpropionate transaminase) [Contains: 4-aminobutyrate aminotransfer [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 4-aminobutyrate aminotransferase, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Abat 4-aminobutyrate aminotransferase, mitochondrial [rat-ipi-250309-contam.fasta] 4-aminobutyrate aminotransferase, mitochondrial OS=Rattus norvegicus GN=Abat [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	500 amino acids
Gene Ontology:
Cellular Component:	synaptosome [IDA] mitochondrial matrix [IEA] mitochondrion [UNKNOWN][IDA][ISS] 4-aminobutyrate transaminase complex [UNKNOWN][ISS]
Biological Process:	gamma-aminobutyric acid catabolic process [IC] response to cocaine [IMP] copulation [IMP] negative regulation of blood pressure [IMP] response to nicotine [IMP] neurotransmitter catabolic process [IC] gamma-aminobutyric acid metabolic process [IEA] response to ethanol [IDA] response to hypoxia [IMP] locomotory behavior [IMP] behavioral response to cocaine [ISS] response to drug [IDA] response to iron ion [IDA]
Molecular Function:	pyridoxal phosphate binding [UNKNOWN][IEA][ISS] protein binding [UNKNOWN][IEA] protein homodimerization activity [UNKNOWN][ISS] 4-aminobutyrate transaminase activity [UNKNOWN][IDA][IEA][ISS] catalytic activity [IEA] (S)-3-amino-2-methylpropionate transaminase activity [IEA] succinate-semialdehyde dehydrogenase binding [ISS] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFLLTTRRL VCSSQKNLHL FTPGSRYISQ AAAKVDFEFD YDGPLMKTEV PGPRSQELMK  60
   61 QLNTIQNAEA VHFFCNYEES RGNYLVDVDG NRMLDLYSQI SSVPIGYNHP ALAKLVQQPQ 120
  121 NASTFINRPA LGILPPENFV DKLRESLMSV APKGMCQLIT MACGSCSNEN AFKTIFMWYR 180
  181 SKERGQRGFS KEELETCMVN QSPGCPDYSI LSFMGAFHGR TMGCLATTHS KAIHKIDIPS 240
  241 FDWPIAPFPR LKYPLEEFVT DNQQEEARCL EEVEDLIVKY RKKKRTVAGI IVEPIQSEGG 300
  301 DNHASDDFFR KLRDIARKHG CAFLVDEVQT GGGCTGKFWA HEHWGLDDPA DVMSFSKKMM 360
  361 TGGFFHKEEF RPSAPYRIFN TWLGDPSKNL LLAEVINIIK REDLLNNVAH AGKTLLTGLL 420
  421 DLQAQYPQFV SRVRGRGTFC SFDTPDEAIR NKLILIARNK GVVLGGCGDK SIRFRPTLVF 480
  481 RDHHAHLFLN IFSGILADFK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.91

Protein Overview: GABT_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: