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Protein Overview: nuo-2

General Information:
Name(s) found: nuo-2 / CE37406 [WormBase]
Description(s) found:
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  • WBGene00020417 locus:nuo-2 status:Confirmed UniProt:O01602 protein_id:CCD68106.1 [WormBase]
  • gi|71990788|ref|NP_491881.2| NADH Ubiquinone Oxidoreductase family member (nuo-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|51988139|gb|AAB52474.2| Hypothetical protein T10E9.7a [Caenorhabditis elegans] [NCBI NR]
  • Hypothetical protein T10E9.7a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE37406 WBGene00020417 locus:nuo-2 NADH-ubiquinone oxidoredutase 30 kd subunit status:Partially_confirmed TR:O01602 protein_id:AAB52474.2 [wormpep150.fasta]
  • CE37406 WBGene00020417 NADH-ubiquinone oxidoredutase 30 kd subunit status:Partially_confirmed TR:O01602 protein_id:AAB52474.2 [wormpep132.fasta]
  • 37406 WBGene00020417 locus:nuo-2 NADH-ubiquinone oxidoredutase 30 kd subunit status:Partially_confirmed TR:O01602 protein_id:AAB52474.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE37406 WBGene00020417 locus:nuo-2 NADH-ubiquinone oxidoredutase 30 kd subunit status:Confirmed UniProt:O01602_CAEEL protein_id:AAB52474.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE37406 WBGene00020417 locus:nuo-2 NADH-ubiquinone oxidoredutase 30 kd subunit status:Confirmed UniProt:O01602_CAEEL protein_id:AAB52474.2| [wormORF-contam.fasta]
  • NADH Ubiquinone Oxidoreductase family member (nuo-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE37406 WBGene00020417 locus:nuo-2 NADH-ubiquinone oxidoredutase 30 kd subunit status:Confirmed TR:O01602 protein_id:AAB52474.2 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE37406 WBGene00020417 locus:nuo-2 NADH-ubiquinone oxidoredutase 30 kd subunit status:Confirmed UniProt:O01602 protein_id:AAB52474.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE37406 WBGene00020417 locus:nuo-2 NADH-ubiquinone oxidoredutase 30 kd subunit status:Confirmed UniProt:O01602 protein_id:CCD68106.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE37406 WBGene00020417 locus:nuo-2 status:Confirmed UniProt:O01602 protein_id:CCD68106.1 [wormpep246-ecoli-contam.fasta]
  • NADH Ubiquinone Oxidoreductase OS=Caenorhabditis elegans GN=nuo-2 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 445 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    Biological Process: electron transport [IEALink to PubMed article]
    mitochondrial electron transport, NADH to ubiquinone [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: NADH dehydrogenase (quinone) activity [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]
    metal cluster binding [IEALink to PubMed article]
    NADH dehydrogenase (ubiquinone) activity [IEALink to PubMed article]
    oxidoreductase activity, acting on NADH or NADPH [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSEILNYPI HRFLDSSLLG QFIGPEGSNI YKIEKYNKVA LDIWKNDEEN SNVRITGPYW  60
   61 NLKSALNDVL ELVSTIRNKN QRYKFEMPSK DIGFLIGKNG AKINEIKLSS NVDVHFERNN 120
  121 ENRDNGETDG RVVVSVTGNY QQILIGLRLI YDRLTSKGQK TLYEDPRTRQ FAESLMKMLG 180
  181 SVIRQAVSRQ IVRNSPISTT AAVAQTNQTG DKKESPKKPT IWKIDEHKRE RLANFGKYAA 240
  241 ECLPKFVQKV QFAAGDELEL LIHPSGVVPV LSFLKGNHSA QFTNLTFITG MDVPTRKNRL 300
  301 EVIYSLYSVR FNARVRVRTY TDEIAPIDSA TPVFKGADWF EREVYDMYGV WFNNHPDLRR 360
  361 ILTDYGFEGH PFRKDYPLSG YNEVRYDPEL KRVVYEPSEL AQEFRKFDLN TPWETFPAFR 420
  421 NQSITSGYET ILEVAEPTPA TPQNK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] PSI-BLAST 32.09691 No description for 2annA was found.
    2 View Details [187..279] deduced N/A No confident structure predictions are available.
    3 View Details [280..445] PSI-BLAST 27.09691 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle