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Protein Overview: EG11043

General Information:
Name(s) found: tyrS / EG11043 [EcoGene]
Description(s) found:
Found 4 descriptions.
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  • tyrosyl-tRNA synthetase / Tyrosine--tRNA ligase [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 424 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [IDALink to PubMed article]
    membrane [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: tRNA aminoacylation for protein translation [IEA]
    tyrosyl-tRNA aminoacylation [IEA]
    translation [IEA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    tyrosine-tRNA ligase activity [IEA]
    aminoacyl-tRNA ligase activity [IEA]
    RNA binding [IEA]
    ligase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSNLIKQL QERGLVAQVT DEEALAERLA QGPIALYCGF DPTADSLHLG HLVPLLCLKR  60
   61 FQQAGHKPVA LVGGATGLIG DPSFKAAERK LNTEETVQEW VDKIRKQVAP FLDFDCGENS 120
  121 AIAANNYDWF GNMNVLTFLR DIGKHFSVNQ MINKEAVKQR LNREDQGISF TEFSYNLLQG 180
  181 YDFACLNKQY GVVLQIGGSD QWGNITSGID LTRRLHQNQV FGLTVPLITK ADGTKFGKTE 240
  241 GGAVWLDPKK TSPYKFYQFW INTADADVYR FLKFFTFMSI EEINALEEED KNSGKAPRAQ 300
  301 YVLAEQVTRL VHGEEGLQAA KRITECLFSG SLSALSEADF EQLAQDGVPM VEMEKGADLM 360
  361 QALVDSELQP SRGQARKTIA SNAITINGEK QSDPEYFFKE EDRLFGRFTL LRRGKKNYCL 420
  421 ICWK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..319] PSI-BLAST 94.522879 Tyrosyl t-RNA Synthetase from E.coli Complexed with Tyrosine
    2 View Details [320..424] PSI-BLAST 18.69897 Tyrosyl-trna synthetase (TyrRS), C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • structural constituent of ribosome
    		•  4.38130670432475 bayes_pls_golite062009
  • structural molecule activity
    		•  4.02543122782129 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.926923419656671 bayes_pls_golite062009
  • binding
    		•  0.803280718980961 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle